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戴世光 醫師


  • 頭頸部(口腔、咽、喉)腫瘤之診斷與治療
  • 頸部腫塊(甲狀腺、唾液腺腫瘤)之診斷與治療
  • 頭頸部達文西機械手臂微創手術
  • 打鼾及睡呼吸中止症候群之診斷及治療
  • 嗓音異常之診斷及治療



喉頭頸科 主治醫師













國立陽明大學醫學院醫學系 醫學士

國立陽明大學醫學院臨床醫學研究所 博士



國立陽明大學醫學院醫學系專任教授兼科主任 –現任











1. Cheng HY, Hsieh CH, Lin PH, Chen YT, Hsu DS, Tai SK, Chu PY, Yang MH. (2022) Snail-regulated exosomal microRNA-21 suppresses NLRP3 inflammasome activity to enhance cisplatin resistance. J Immunother Cancer 2022 Aug;10(8):e004832. doi: 10.1136/jitc-2022-004832.

2. Lee TL, Wei PY, Tai SK*. (2022) Effect of local anesthesia on pain scale and specimen adequacy in fine-needle aspiration biopsy of thyroid nodules for liquid-based cytology. Sci Rep 2022 Nov 2;12(1):18498. doi: 10.1038/s41598-022-23031-0.

3. Lee TL, Lee YT, Tai SK*. (2022) Neck management in T1-2 early-stage oral squamous cell carcinoma. International Journal of Head and Neck Science 2022;6(2):45-56.

4. Lai CL, Chen TH, Chang PM, Tai SK, Chu PY, Yang MH. (2022) Efficacy of cetuximab-containing regimens in the treatment of recurrent/metastatic head and neck cancer after progression to immune checkpoint inhibitors. J Chin Med Assoc 85(6):687-692.

5. Lee TL, Wei PY, Yang MH, Chang PM, Wang LW, Tai SK*. (2022) Tongue conservation treatment for oral tongue squamous cell carcinoma with induction chemotherapy, surgery, and risk-adapted adjuvant therapy: A phase II trial. Cancer Rep (Hoboken) 2022 Feb;5(2):e1456.

6. Ting KC, Lee TL, Li WY, Chang CF, Chu PY, Wang YF, Tai SK*. (2021) Perineural invasion/lymphovascular invasion double positive predicts distant metastasis and poor survival in T3-4 oral squamous cell carcinoma. Sci Rep 11(1):19770.

7. Huang YW, Wang YP, Lee TL, Chang CF, Hou MC, Tai SK, Chu PY. (2021) Image-enhanced endoscopy for detection of second primary esophageal neoplasms in patients with hypopharyngeal cancer: Prevalence, risk factors, and characteristics. J Chin Med Assoc 84(10):963-968

8. Lee TL, Wei PY, Yang MH, Chang PM, Wang LW, Tai SK*. (2021) Tongue conservation treatment for oral tongue squamous cell carcinoma with induction chemotherapy, surgery, and risk-adapted adjuvant therapy: A phase II trial. Cancer Rep (Hoboken). 2021 May 29:e1456.

9. Wu HL, Chu YH, Tai YH, Tsou MY, Wu CH, Lo WL, Tai SK, Yeh CC, Lu CC. (2020) Stage-dependent angiopoietin-Tie2 and nitric oxide signaling of erythrocytes in response to surgical trauma in head and neck cancer. World J Surg Oncol 18(1):209.

10. Yang CF, Niu DM, Tai SK, Wang TH, Su HT, Huang LY, Soong WJ. (2020) Airway abnormalities in very early treated infantile-onset Pompe disease: A large-scale survey by flexible bronchoscopy. Am J Med Genet A 182(4):721-729.

11. Lee TL, Chiu PH, Li WY, Yang MH, Wei PY, Chu PY, Wang YF, Tai SK*. (2019) Nerve-tumour interaction enhances the aggressiveness of oral squamous cell carcinoma. Clin Otolaryngol 44(6):1087-1095.

12. Wei PY, Li WY, Tai SK*. (2019) Discrete perineural invasion (PNI) focus number in PNI quantification for T1-2 oral squamous cell carcinoma. Otolaryngol Head Neck Surg 160(4):635-641.

13. Li CF, Chen JY, Ho YH, Hsu WH, Wu LC, Lan HY, Hsu DS, Tai SK, Chang YC, Yang MH. (2019) Snail-induced Claudin-11 prompts collective migration for tumor progression. Nat Cell Biol 21(2):251-262.

14. Lee CC, Lin JC, Hwang WL, Kuo YJ, Chen HK, Tai SK, Lin CC, Yang MH. (2018) Macrophage-secreted interleukin-35 regulates cancer cell plasticity to facilitate metastatic colonization. Nat Commun 9(1):3763.

15. Hsieh CH, Tai SK, Yang MH. (2018) Snail-overexpressing cancer cells promote M2-Like polarization of tumor-associated macrophages by delivering MiR-21-abundant exosomes. Neoplasia 20(8):775-788.

16. Chen SC, Chang PM, Wang HJ, Tai SK, Chu PY, Yang MH. (2018) PD-L1 expression is associated with p16INK4A expression in non-oropharyngeal head and neck squamous cell carcinoma. Oncol Lett 15(2):2259-2265.

17. Chang PM, Chen CH, Yeh CC, Lu HJ, Liu TT, Chen MH, Liu CY, Wu ATH, Yang MH, Tai SK, Mochly-Rosen D, Huang CF. (2018) Transcriptome analysis and prognosis of ALDH isoforms in human cancer. Sci Rep 8(1):2713

18. Lu YT, Tai SK*, Lee TL*. (2018) Pterygomandibular suspension suture: a simple modification of uvulopalatopharyngoplasty for severe obstructive sleep apnea. Eur Arch Otorhinolaryngol 275(1):269-273.




1. 戴世光、李永賢、朱本元、羅文良、吳政憲、許彥彬、李宗倫:頭頸鱗狀上皮癌神經旁侵犯之定量分析與臨床表現。 2012/1~2012/12  台北榮總  V101C-057

2. 戴世光、呂春敏:CLEC17A在B細胞之表現與作用。 2012/1~2012/12  台北榮總 V101E4-005

3. 戴世光、楊慕華:頭頸癌上皮間質轉化與Hippo 訊息交互影響之研究。2012/8~2015/7  國科會 NSC 101-2314-B-010 -021 -MY3

4. 戴世光、楊慕華、謝世良:第三號誘餌受體直接促進腫瘤生長之研究。 2013/1~2013/12  台北榮總 V102C-087

5. 戴世光、楊慕華、陽光耀:Decoy receptor 3 對於頭頸鱗狀上皮癌微型核醣核酸表達調控之影響。 2013/1~2013/12  台北榮總 V102E4-004

6. 戴世光、楊慕華:Krupple-like factor 4 調控cortactin 並促進頭頸鱗狀上皮癌細胞之行動侵犯能力。 2014/1~2014/12  台北榮總 V103C-017

7. 戴世光、楊慕華:探討癌細胞發生上皮間質轉化時引發宿主細胞吸附的機制。 2014/1~2014/12  台北榮總 V103E4-004

8. 戴世光:頭頸鱗狀細胞癌神經旁侵犯之初步實驗研究。 2015/1~2015/12  台北榮總 V104C-002

9. 戴世光、楊慕華:許旺細胞在頭頸鱗狀細胞癌神經旁侵犯所扮演角色之機轉研究。2015/8~2016/7  科技部 MOST 104-2314-B-010 -053 -