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王復德 顧問

 

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姓名

王復德 顧問

學歷

高雄醫學院醫學系醫學士

教職

國立陽明交通大學醫學系內科學科兼任教授

國立陽明交通大學公共衛生研究所合聘教授

現職

台北醫學大學附設醫院感染科主治醫師

臺北榮民總醫院 內科部感染科特約醫師

臺北榮民總醫院 內科部教授級醫師

臺北榮民總醫院 專業諮詢委員

台灣感染症醫學會理事長

台灣感染管制學會理事

經歷

臺北榮民總醫院 內科部感染科主任

臺北榮民總醫院 感染管制室主任

臺北榮民總醫院 內科部感染科總醫師

臺北榮民總醫院 內科部住院醫師

專科證書

中華民國內科專科醫師

中華民國感染症專科醫師

醫療專長

感染管制、感染症學、微生物學、細菌毒性及抗藥性、愛滋病、一般內科

語言專長

國語/英語/台語

著作

  1. Lin YT, Wang FD, Chan YJ, Fu YC, Fung CP. Clinical and microbiological characteristics of tigecycline non-susceptible Klebsiella pneumoniae bacteremia in Taiwan. BMC Infect Dis 2014;14:1.
  2. Wang FD, Liao CH, Lin YT, Sheng WH, Hsueh PR. Trends in the susceptibility of commonly encountered clinically significant anaerobes and susceptibilities of blood isolates of anaerobes to 16 antimicrobial agents, including fidaxomicin and rifaximin, 2008-2012, northern Taiwan. Eur J Clin Microbiol Infect Dis. 2014;33:2041-52.
  3. Yi-Tsung Lin*, Yu-Ping Wang, Fu-Der Wang and Chang-Phone Fung. Community-onset Klebsiella pneumoniae pneumonia in Taiwan: clinical features of the disease and associated microbiological characteristics of isolates from pneumonia and nasopharynx. Frontiers in MICROBIOLOGY. 18February2015 doi: 10.3389/fmicb.2015.00122
  4. Ku WW, Kung CH, Lee CH, Tseng CP, Wu PF, Kuo SC, Chen TL, Lee YT, Wang FD, Fung CP. Evolution of carbapenem resistance in Acinetobacter baumannii: An 18-year longitudinal study from a medical center in northern Taiwan. J Microbiol Immunol Infect. 2015;48:57-64.
  5. Lee WS, Hsieh TC, Ou TY, Teng SO, Chen FL, Wang FD*. Breakthrough disseminated crytpococcus during micafungin therapy. J Microbiol Immunol Infect 2015 Aug;48(4):456-8.
  6. Chen LY, Yang SP, Chen TL, Liao SY, Chen YY, Chan YJ, Chen LK, Wang FD*. Clinical significance of time to positive for yeast in candidemia. J Microbiol Immunol Infect 2015 Aug;48(4):425-30.
  7. Wu PF, Chang YY, Lin YT, Wang FD, Chan YJ, Fung CP. Clinical characteristics and economic consequence of Klebsiella pneumoniae liver abscess in Taiwan. J Microbiol Immunol Infect. 2015 Apr;48(2):190-7.
  8. Jann-Tay Wang, Le-Yin Hsu, Tsai-Ling Lauderdale, Wen-Chien Fan, Fu-Der Wang*. Comparison of Outcomes among Adult Patients with Nosocomial Bacteremia Caused by Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus: A Retrospective Cohort Study, PLOS ONE | DOI:10.1371/journal.pone.0144710 December 21, 2015
  9. Chih-Han Juan, Yi-Wei Huang, Yi-Tsung Lin, Tsuey-Ching Yang, Fu-Der Wang. Risk Factors, Outcomes, and Mechanisms of Tigecycline-Nonsusceptible Klebsiella pneumoniae Bacteremia. Antimicrob Agent Chemother 2016; 60: 7357-63
  10. Chien Chuang, Wen?Chien Fan, Yi?Tsung Lin* and Fu?Der Wang. The emergence of Klebsiella pneumoniae liver abscess in non?diabetic patients and the distribution of capsular types. Gut Pathog (2016) 8:46.
  11. Chung-Chih Lai, Zhi-Yuan Shi, Yen-Hsu Chen,* Fu-Der Wang.**  Effects of various antimicrobial stewardship programs on antimicrobial usage and resistance among common gram-negative bacilli causing health care-associated infections: A multicenter comparison. J Microbiol Immunol Infect (2016) 49, 74-82
  12. Yi-Tsung Lin,* Yi-Wei Huang, Hsin-Hui Huang, Tsuey-Ching Yang, Fu-Der Wang, Chang-Phone Fung. In vivo evolution of tigecycline-non-susceptible Klebsiella pneumoniae strains in patients: relationship between virulence and resistance. International Journal of Antimicrobial Agents 48 (2016) 485–491
  13. Ping-Feng Wu, Chien Chuang, Chin-Fang Su, Yi-Tsung Lin, Yu-Jiun Chan, Fu-Der Wang, Yin-Ching Chuang, L. Kristopher Siu & Chang-Phone Fung.  High minimum inhibitory concentration of imipenem as a predictor of fatal outcome in patients with carbapenem nonsusceptible Klebsiella pneumoniae.  Scientific Reports | 6:32665 | DOI: 10.1038/srep32665
  14. Yin-Yin Chen, Wan-Tsuei Huang, Chia-Ping Chen, Shu-Mei Sun, Fu-Mei Kuo, Yu-Jiun Chan, Shu-Chen Kuo, Fu-Der Wang*. An Outbreak of Ralstonia pickettii Bloodstream Infection Associated with an Intrinsically Contaminated Normal Saline Solution. Infect Control Hosp Epidemiol 2017;1–5
  15.  Ping-Feng Wu, Wei-Lun Liu, Min-Han Hsieh, Ing-Moi Hii, Yu-Lin Lee, Yi-Tsung Lin, Mao-Wang Ho, Chun-Eng Liu, Yen-Hsu Chen and Fu-Der Wang*. Epidemiology and antifungal susceptibility of candidemia isolates of non-albicans Candida species from cancer patients. Emerging Microbes & Infections (2017) 6, e87; doi:10.1038/emi.2017.74
  16. Shiang-Fen Huang, Chang-Phone Fung, Diahn-Warng Perng, Fu-Der Wang,* Effects of corticosteroid and neuraminidase inhibitors on survival in patients with respiratory distress induced by influenza virus. J Microbiol Immunol Infect. 2017 Oct;50(5):586-594
  17. Mark H. Wilcox, M.D., Dale N. Gerding, M.D., Ian R. Poxton, Ph.D., Ciaran Kelly, M.D., Richard Nathan, D.O., Thomas Birch, M.D., Oliver A. Cornely, M.D., Galia Rahav, M.D., Emilio Bouza, M.D., Christine Lee, M.D., Grant Jenkin, M.D., Werner Jensen, M.D., You-Sun Kim, M.D., Junichi Yoshida, M.D., Lori Gabryelski, B.S.M.T., Alison Pedley, Ph.D., Karen Eves, B.S., Robert Tipping, M.S., Dalya Guris, M.D., Nicholas Kartsonis, M.D., and Mary-Beth Dorr, Ph.D. et al., for the MODIFY I and MODIFY II Investigators*. Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection. N Engl J Med 2017; 376:305-317
  18. Wei-Lu, Su-Jung Chen, Shiang-Fen Huang, Yu-Jiun Chan, Fu-Der Wang, Hsin-Pai Chen.* Clinical significance of human cytomegalovirus viruria and the effect of antiviral therapy in hematopoietic stem cell transplant recipients. J Microbiol Immunol Infect. 2017 (article in press).
  19. Fu Shaw L, Chen IH, Chen CS, Wu HH, Lai LS, Chen YY, Wang FD. Factors influencing microbial colonies in the air of operating rooms. BMC Infect Dis. 2018 Jan 2;18(1):4. doi: 10.1186/s12879-017-2928-1.
  20. Ping-Feng Wu, Yi-Tsung Lin*, Fu-Der Wang*, Tsuey-Ching Yang, Chang-Phone Fung. Is fluoroquinolone monotherapy a useful alternative treatment for Pseudomonas aeruginosa bacteraemia? Infection. 2018 Jun;46(3):365-373.
  21. Ying-Chi Huang, Yi-Tsung Lin, Fu-Der Wang. Comparison of the therapeutic efficacy of fluoroquinolone and non-fluoroquinolone treatment in patients with Elizabethkingia meningoseptica bacteraemia. International Journal of Antimicrobial Agents 51 (2018) 47–51.
  22.  Yi-Tsung Lin, Yi-Hsiang Cheng , Chih-Han Juan , Ping-Feng Wu, Yi-Wei Huang, Sheng-Hua Chou, Tsuey-Ching Yang, Fu-Der Wang. High mortality among patients infected with hypervirulent antimicrobial-resistant capsular type K1 Klebsiella pneumoniae strains in Taiwan. International Journal of Antimicrobial Agents 52 (2018) 251–257.
  23. Lai CC, Lin YT, Lin YT, Lu MC, Shi ZY, Chen YS, Wang LS, Tseng SH, Lin CN, Chen YH, Ko WC, Wang FD*, Hsueh PR; Infection Control Society of Taiwan. Clinical characteristics of patients with bacteraemia due to the emergence of mcr-1 -harbouring Enterobacteriaceae in humans and pigs in Taiwan. Int J Antimicrob Agents. 2018; 52(5):651-657. (IF: 4.253) #Chih-Cheng Lai and Yi-Tsung Lin contributed to this manuscript equally
  24. Po-Liang Lu, Wei-Lun Liu, Hsiu-Jung Lo, Fu-Der Wang, Wen-Chien Ko, Po-Ren Hsueh, Mao-Wang Ho, Chun-Eng Liu, Yen-Hsu Chen, Yee-Chun Chen, Yin-Ching Chuang, Shan-Chwen Chang. Are we ready for the global emergence of multidrug-resistant Candida auris in Taiwan? Journal of the Formosan Medical Association (2018) 117, 462-470.
  25. Wu PS, Chuang C, Wu PF, Lin YT*, Wang FD. Anaerobic coverage as definitive therapy does not affect clinical outcomes in community-onset bacteremic biliary tract infection without anaerobic bacteremia. BMC Infect Dis.2018; 18(1):277. (IF: 2.620)
  26. Wang FD*, Wang YP, Chen CF, Chen HP. The incidence rate, trend and microbiological aetiology of prosthetic joint infection after total knee arthroplasty: A 13 years’ experience from a tertiary medical center in Taiwan. J Microbiol Immunol Infect. 2018; 51(6):717-722. (IF: 2.094) #Fu-Der Wang and Yu-Ping Wang contributed to this manuscript equally.
  27. Yeh CY, Wang FD, Chuang YC, Yang CJ, Huang SF, Weng WS, Liaw CH, Sheng WH*. Clinical outcomes and prognostic factors of patients with severe influenza receiving intravenous peramivir salvage therapy in intensive care units. J Microbiol Immunol Infect. 2018; 51(6):697-704. (IF: 2.094)
  28. Huang SF, Chen MH, Wang FD, Tsai CY, Fung CP*, Su WJ*. Efficacy of isoniazid salvage therapy for latent tuberculosis infection in patients with immune-mediated inflammatory disorders - A retrospective cohort study in Taiwan. J Microbiol Immunol Infect. 2018; 51(6):784-793. (IF: 2.094)
  29. Wang HY*,, Yang CF, Chiou TJ, Gau JP, Chen PM, Tsai CY, Hsu HC, Wang FD, Liu JH, Hsiao LT*,. Primary bone marrow lymphoma: A hematological emergency in adults with fever of unknown origin. Cancer Med. 2018; 7(8):3713-3721. (IF: 3.202)
  30. Jean SS, Lu MC, Shi ZY, Tseng SH, Wu TS, Lu PL, Shao PL, Ko WC, Wang FD*, Hsueh PR. In vitro activity of ceftazidime–avibactam, ceftolozane–tazobactam, and other comparable agents against clinically important Gram-negative bacilli: results from the 2017 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART). Infect Drug Resist. 2018; 11:1983-1992. (IF: 3.443)
  31. Jean SS, Lu MC, Shi ZY, Tseng SH, Wu TS, Lu PL, Shao PL, Ko WC, Wang FD, Hsueh PR. In vitro activity of ceftazidime-avibactam, ceftolozane-tazobactam, and other comparable agents against clinically important Gram-negative bacilli: results from the 2017 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART). Infect Drug Resist. 2018 Oct 26;11:1983-1992.
  32. Fu-Der Wang*, Ping-Feng Wu, Su-Jung Chen. Distribution of virulence genes in bacteremic methicillin-resistant Staphylococcus aureus isolates from various sources. Journal of Microbiology, Immunology and Infection 2019;52: 426-432.
  33. Wei-Lun Liu , Yu-Tsung Huang , Min-Han Hsieh , Ing-Moi Hii , Yu-Lin Lee , Mao-Wang Ho , Chun-Eng Liu , Yen-Hsu Chen , Fu-Der Wang . Clinical characteristics of Candida tropicalis fungaemia with re duce d triazole susceptibility in Taiwan: a multicentre study. International Journal of Antimicrobial Agents 2019; 53 :185–189
  34. Ing-Moi Hii, Chun-Eng Liu,Yu-Lin Lee, Wei-Lun Liu, Ping-Feng Wu, Min-Han Hsieh, Mao-Wang Ho, Yen-Hsu Chen, Fu-Der Wang*.  Resistance rates of non-albicans Candida infections in Taiwan after the revision of 2012 Clinical and Laboratory Standards Institute breakpoints. Infection and Drug Resistance 2019;12; 235–240
  35. Chen YT, Lee WS, Tsai CA, Fan WC, Wu PF, Wang FD*. Incidence of and risk factors for cryptococcosis in kidney transplant recipients in Taiwan-A nationwide population-based study. Int J Infect Dis. 2019 Nov;88:154-158.
  36. Lu W, Chen HP, Chan YJ, Wang FD. Clinical significance of post-treatment viral load of cytomegalovirus in patients with hematologic malignancies. J Microbiol Immunol Infect. 2019 Aug 6. pii: S1684-1182
  37. Lee YL, Lu MC, Shao PL, Lu PL, Chen YH, Cheng SH, Ko WC, Lin CY, Wu TS, Yen MY, Wang LS, Liu CP, Lee WS, Shi ZY, Chen YS, Wang FD, Tseng SH, Lin CN, Chen YH, Sheng WH, Lee CM, Liao MH, Hsueh PR. Nationwide surveillance of antimicrobial resistance among clinically important Gram-negative bacteria, with an emphasis on carbapenems and colistin: Results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART) in 2018. Int J Antimicrob Agents. 2019 Sep;54(3):318-328.
  38. Liu JW, Chen YH, Lee WS, Lin JC, Huang CT, Lin HH, Liu YC, Chuang YC, Tang HJ, Chen YS, Ko WC, Lu MC, Wang FD*. Randomized Noninferiority Trial of Cefoperazone-Sulbactam versus Cefepime in the Treatment of Hospital-Acquired and Healthcare-Associated Pneumonia. Antimicrob Agents Chemother. 2019 Jul 25;63(8). pii: e00023-19.
  39. Huang SF, Yang YY, Chou KT, Fung CP, Wang FD, Su WJ. Systemic proinflammation after Mycobacterium tuberculosis infection was correlated to the gut microbiome in HIV-uninfected humans. Eur J Clin Invest. 2019 May;49(5):e13068.
  40. Huang YC, Wu PF, Lin YT, Wang FD. Comparison of clinical characteristics of bacteremia from Elizabethkingia meningoseptica and other carbapenem-resistant, non-fermenting Gram-negative bacilli at a tertiary medical center. J Microbiol Immunol Infect. 2019 Apr;52(2):304-311
  41. Hsin-Hui Huang, Su-Jung Chen, Tze-Fan Chao, Chia-Jen Liu, Tzeng-Ji Chen, Pesus Chou j, Fu-Der Wang.* Influenza vaccination and risk of respiratory failure in patients with chronic obstructive pulmonary disease: A nationwide population-based case-cohort study. Journal of Microbiology, Immunology and Infection (2019) 52, 22e29.
  42.  Shu-Chen Kuo, Chun-Eng Liu, Po-Liang Lu, Yao-Shen Chen , Min-Chi Lu , Wen-Chien Ko, Po-Ren Hsueh, Yin-Ching Chuang, Fu-Der Wang*, the SMART Asia-Pacific Group † Activity of ceftolozane-tazobactam against Gram-negative pathogens isolated from lower respiratory tract infections in the Asia-Pacific region: SMART 2015-2016. International Journal of Antimicrobial Agents 55 (2020) 105883
  43. Yin-Yin Chen, Ping-Feng Wu, Chii-Shya Chen, Ian-Horng Chen, Wan-Tsuei Huang and Fu-Der Wang*.  Trends in microbial profile of burn patients following an event of dust explosion at a tertiary medical center. BMC Infectious Diseases (2020) 20:193
  44. Yung-Chih Wang , Wen-Wei Ku, Ya-Sung Yang, Chih-Chun Kao, Fang-Yu Kang, Shu-Chen Kuo, Chun-Hsiang Chiu, Te-Li Chen, Fu-Der Wang and Yi-Tzu Lee* Is Polymicrobial Bacteremia an Independent Risk Factor for Mortality in Acinetobacter baumannii Bacteremia?  J. Clin. Med. 2020, 9, 153
  45.  Jien-Wei Liu, Yen-Hsu Chen, Wen-Sen Lee, Jung-Chung Lin, Ching-Tai Huang, Hsi-Hsun Lin, Yung-Ching Liu,Yin-Ching Chuang, Hung-Jen Tang, Yao-Shen Chen, Wen-Chien Ko, Min-Chi Lu, Fu-Der Wang*. Reply to Zhou and Wu, “Be Careful with Adverse Events Caused by Cefoperazone-Sulbactam”. Antimicrobial Agents and Chemotherapy February 2020 Volume 64 Issue 2 e02028-19
  46. Chuang C, Chou SH, Wang FD, Huang YH, Tsai TH, Lin YT. Fluoroquinolones as an alternative treatment for Klebsiella pneumoniae liver abscess and impact on hospital length of stay. Int J Antimicrob Agents. 2020 Oct;56(4):106120.
  47. Chen KL, Wang SJ, Chuang C, Huang LY, Chiu FY, Wang FD, Lin YT, Chen WM. Novel Design for Door Handle-A Potential Technology to Reduce Hand Contamination in the COVID-19 Pandemic. Am J Med. 2020; 133(11):1245-1246.
  48. Shiang SF, Li SY, Chan YJ, Huang YC, Yang YY, Fu-Der Wang*. Diagnostic cut-off value for Aspergillus fumigatus- and flavus-specific IgG with clinical relevance in chronic pulmonary Aspergillus infection: A pilot study in Taiwan. Mycoses. 2020 Oct;63(10):1083-1093.
  49. Jean SS, Hsueh PR; SMART Asia-Pacific Group. Antimicrobial susceptibilities of the ertapenem-non-susceptible non-carbapenemase-producing Enterobacterales isolates causing intra-abdominal infections in the Asia-Pacific region during 2008-2014: Results from the Study for Monitoring the Antimicrobial Resistance Trends (SMART). J Glob Antimicrob Resist. 2020 Jun;21:91-98.
  50. Huang YS, Wang FD, Chen YC, Huang YT, Hsieh MH, Hii IM, Lee YL, Ho MW, Liu CE, Chen YH, Liu WL. High rates of misidentification of uncommon Candida species causing bloodstream infections using conventional phenotypic methods. J Formos Med Assoc. 2020 Nov 27:S0929-6646(20)30550-7.
  51. Wang YC, Huang SW, Chiang MH, Lee IM, Kuo SC, Yang YS, Chiu CH, Su YS, Chen TL, Wang FD, Lee YT. In vitro and in vivo activities of imipenem combined with BLI-489 against class D β-lactamase-producing Acinetobacter baumannii. J Antimicrob Chemother. 2020 Oct 14:dkaa421.
  52. Liu PY, Lee YL, Lu MC, Shao PL, Lu PL, Chen YH, Cheng SH, Ko WC, Lin CY, Wu TS, Yen MY, Wang LS, Liu CP, Lee WS, Chen YS, Wang FD, Tseng SH, Lin CN, Tang HJ, Chen YH, Sheng WH, Lee CM, Liao MH, Hsueh PR. National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART). Antimicrob Agents Chemother. 2020 Sep 21;64(10):e01089-20.
  53. Chen KL, Wang SJ, Chuang C, Huang LY, Chiu FY, Wang FD, Lin YT, Chen WM. Novel Design for Door Handle-A Potential Technology to Reduce Hand Contamination in the COVID-19 Pandemic. Am J Med. 2020 Nov;133(11):1245-1246.
  54. Hung JJ, Wang FD, Ma H, Tsou MY, Dai HD, Lin YH, Chen WM, Liu CS. Precaution strategy toward the COVID-19 pandemic in the operating room of a tertiary hospital in Taiwan. J Chin Med Assoc. 2020 Nov 9.
  55. Huang SF, Huang YC, Chang FY, Lin JC, Chiu CH, Chen CW, Wang FD, Chiu YL, Cheng SH, Cheng CY, Lin YC, Chen CP, Huang CH, Liu PY, Lee YT, Lee CH, Chen YS, Sy CL, Tseng YT, Hsu CT, Tseng CC, Lee YL, Liu CE, Sytwu HK. Rapid establishment of a COVID-19 biobank in NHRI by National Biobank Consortium of Taiwan. Biomed J. 2020 Aug;43(4):314-317.
  56. Wu KS, Syue LS, Cheng A, Yen TY, Chen HM, Chiu YH, Hsu YL, Chiu CH, Su TY, Tsai WL, Chen WY, Huang CH, Hung HM, Huang LJ, Kuo HJ, Lin PC, Yang CH, Hong PL, Lee SS, Chen YS, Liu YC, Huang LM; Infectious Diseases Society of Taiwan; Medical Foundation in Memory of Dr. Deh-Lin Cheng; Foundation of Professor Wei-Chuan Hsieh for Infectious Diseases Research and Education; CY Lee's Research Foundation for Pediatric Infectious Diseases and Vaccines; 5th Guidelines Recommendations for Evidence-based Antimicrobial agents use in Taiwan (GREAT) working group. Recommendations and guidelines for the treatment of Clostridioides difficile infection in Taiwan. J Microbiol Immunol Infect. 2020 Apr;53(2):191-208.
  57. Jean SS, Ko WC, Hsueh PR; SMART Study Group. Susceptibility of clinical isolates of meticillin-resistant Staphylococcus aureus and phenotypic non-extended-spectrum β-lactamase-producing Klebsiella pneumoniae to ceftaroline in Taiwan: Results from Antimicrobial Testing Leadership and Surveillance (ATLAS) in 2012-2018 and Surveillance of Multicentre Antimicrobial Resistance in Taiwan (SMART) in 2018-2019. Int J Antimicrob Agents. 2020 Jul;56(1):106016.
  58. Liu CH, Huang HY, Tu YF, Lai WY, Wang CL, Sun JR, Chien Y, Lin TW, Lin YY, Chien CS, Huang CH, Chen YM, Huang PI, Wang FD, Yang YP. Highlight of severe acute respiratory syndrome coronavirus-2 vaccine development against COVID-19 pandemic. J Chin Med Assoc. 2021 Jan 1;84(1):9-13.
  59. Chen PL, Hsiao YH, Chuang C, Feng JY, Ho HL, Lin YT, Chen SJ, Huang SF, Chen HP, Chou TY, Chen YM, Fu-Der Wang*. The Clinical Manifestations and Interval Changes of Reverse-Transcriptase Quantitative Polymerase Chain Reactions among Different Specimens of Coronavirus Disease 2019 Patients. J Chin Med Assoc. February 2021 - Volume 84 - Issue 2 - p 151-157
  60. Ling?Ju Huang, Su?Jung Chen, Yu?Wen Hu, Chun?Yu Liu, Ping?Feng Wu, Shu?Mei Sun, Shih?Yi Lee, Yin?Yin Chen, Chung?Yuan Lee, Yu?Jiun Chan,Yueh?Ching Chou & Fu-Der Wang*. The impact of antimicrobial stewardship program designed to shorten antibiotics use on the incidence of resistant bacterial infections and mortality. Scientific Reports 2022;12:913

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