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林邑璁 主任

 

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姓名

林邑璁 主任

林邑璁 主任

學歷

國立陽明大學醫學系學士

國立陽明大學臨床醫學研究所博士

現職

臺北榮民總醫院感染科主任 (2022.1~)

國立陽明大學急重症醫學研究所專任教授 (2021.2~)

台灣感染症醫學會副秘書長

Journal of Microbiology, Immunology and Infection 執行編輯

BMC Infectious Diseases 副編輯

經歷

臺北榮民總醫院感染科主治醫師 (2012.6~)

署立金門醫院內科主治醫師 (2010.6~2012.5)

臺北榮民總醫院內科部部總醫師 (2009.6~2010.5)

臺北榮民總醫院內科部感染科住院總醫師 (2007.8~2009.6)

臺北榮民總醫院內科部住院醫師 (2004.8~2007.7)

醫療專長

感染症學、微生物學、細菌毒性及抗藥性、愛滋病、一般內科

專科證書

感染症專科醫師

內科專科醫師

語言專長

國語、英語、台語

得獎紀錄

102年醫師節臨床教學績優獎

102實習醫學生票選最佳教學醫師獎

103實習醫學生票選最佳教學醫師獎

103學年度陽明大學106級核心實習臨床優良教師

104實習醫學生票選最佳教學醫師獎

104學年度陽明大學107級核心實習臨床優良教師

105實習醫學生票選最佳教學醫師獎

105學年度陽明大學108級核心實習臨床優良教師

106實習醫學生票選最佳教學醫師獎

106年醫師節臨床教學績優獎

國軍退除役官兵輔導委員會106年臨床教學績優醫師獎

107年度實習醫學生票選最佳教學醫師獎

陽明大學108s級學生票選核心實習臨床優良教師

陽明大學109級學生票選核心實習臨床優良教師

105-109學年度陽明醫學系網路教學評估優良教師

內科部107年度個人績優論文獎

內科部107年度傑出論文獎

國軍退除役官兵輔導委員會108年優良醫師獎

109年度實習醫學生票選最佳教學醫師獎

陽明大學110級學生票選核心實習臨床優良教師

內科部109年度績優研究導師獎

內科部109年度傑出論文獎

110年度實習醫學生票選最佳教學醫師獎

國軍退除役官兵輔導委員會110年臨床教學績優醫師獎

110年度COVID-19疫情期間擔任中央流行疫情指揮中心"COVID-19重症個案臨床處置專家諮詢小組暨相關系列研討會"專家講座

著作

近五年代表性著作

1. Huang YH, Chou SH, Liang SW, Ni CE, Lin YT*, Huang YW, Yang TC. Emergence of an XDR and carbapenemase-producing hypervirulent Klebsiella pneumoniae strain in Taiwan. J Antimicrob Chemother. 2018; 73(8):2039-2046. (*corresponding author, 2021 IF=5.758, Rank 54/279, Pharmacology & Pharmacy)

2. Lin YT*, Cheng YH, Juan CH, Wu PF, Huang YW, Chou SH, Yang TC, Wang FD. High mortality among patients infected with hypervirulent antimicrobial-resistant capsular type K1 Klebsiella pneumoniae strains in Taiwan. Int J Antimicrob Agents. 2018; 52(2):251-257. (*corresponding author, 2021 IF=15.441, Rank 11/94, infectious diseases)

3. Cheng YH, Huang TW, Juan CH, Chou SH, Tseng YY, Chen TW, Yang TC, Lin YT*. Tigecycline-non-susceptible hypervirulent Klebsiella pneumoniae strains in Taiwan. J Antimicrob Chemother. 2020; 75(2):309-317. (*corresponding author, 2021 IF=5.758, Rank 54/279, Pharmacology & Pharmacy)

4. Lin YT*, Cheng YH, Chuang C, Chou SH, Liu WH, Huang CH, Yang TC, Kreiswirth BN, Chen L. Molecular and Clinical Characterization of Multidrug-Resistant and Hypervirulent Klebsiella pneumoniae Strains from Liver Abscess in Taiwan. Antimicrob Agents Chemother. 2020; 64(5):e00174-20. (*corresponding author, 2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

5. Huang PH, Chen WY, Chou SH, Wang FD, Lin YT*. Risk Factors for the Development of Colistin Resistance during Colistin Treatment of Carbapenem-Resistant Klebsiella pneumoniae Infections. Microbiol Spectr. 2022 Jun 29;10(3):e0038122. (*corresponding author, 2021 IF=9.043, Rank: 20/136, microbiology)

 

第一或通訊作者

1. Lin YT, Chan YJ, Chiu CH, Lin ML, Yu KW, Wang FD, Liu CY. Tigecycline and colistin susceptibility of Chryseobacterium meningosepticum isolated from blood in Taiwan. Int J Antimicrob Agents. 2009; 34(1):100-1. (2021 IF=15.441, Rank 11/94, infectious diseases)

2. Lin YT, Chiu CH, Chan YJ, Lin ML, Yu KW, Wang FD, Liu CY. Clinical and microbiological analysis of Elizabethkingia meningoseptica bacteremia in adult patients in Taiwan. Scand J Infect Dis. 2009; 41(9):628-34. (2021 IF=5.838, Rank 31/94, infectious diseases)

3. Lin YT, Chen TL, Siu LK, Hsu SF, Fung CP. Clinical and microbiological characteristics of community-acquired thoracic empyema or complicated parapneumonic effusion caused by Klebsiella pneumoniae in Taiwan. Eur J Clin Microbiol Infect Dis. 2010; 29(8):1003-10. (2021 IF=5.103, Rank 49/136, microbiology)

4. Lin YT, Jeng YY, Chen TL, Fung CP. Bacteremic community-acquired pneumonia due to Klebsiella pneumoniae: Clinical and microbiological characteristics in Taiwan, 2001-2008. BMC Infect Dis. 2010; 10:307. (2021 IF=3.670, Rank 60/94, infectious diseases)

5. Lin YT, Jeng YY, Lin ML, Yu KW, Wang FD, Liu CY. Clinical and microbiological characteristics of Chryseobacterium indologenes bacteremia. J Microbiol Immunol Infect. 2010; 43(6):498-505. (2021 IF=10.273, Rank 17/136, microbiology)

6. Lin YT, Liu CJ, Fung CP, Tzeng CH. Nosocomial Klebsiella pneumoniae bacteraemia in adult cancer patients-characteristics of neutropenic and non-neutropenic patients. Scand J Infect Dis. 2011; 43(8):603-8. (2021 IF=15.441, Rank 11/94, infectious diseases)

7. Lin YT, Liu CJ, Chen TJ, Yeh YC, Wu HS, Tseng CP, Wang FD, Tzeng CH, Fung CP. Pyogenic liver abscess as the initial manifestation of underlying hepatocellular carcinoma. Am J Med. 2011; 124(12):1158-64. (2021 IF=5.928, Rank: 36/172, medicine, general & internal)

8. Lin YT, Siu LK, Lin JC, Chen TL, Tseng CP, Yeh KM, Chang FY, Fung CP. Seroepidemiology of Klebsiella pneumoniae colonizing the intestinal tract of healthy Chinese and overseas Chinese adults in Asian countries. BMC Microbiol. 2012; 12:13 (2021 IF=4.465, Rank 60/136, microbiology)

9. Wu HS, Wang FD, Tseng CP, Wu TH, Lin YT*, Fung CP. Characteristics of healthcare-associated and community-acquired Klebsiella pneumoniae bacteremia in Taiwan. J infect. 2012; 64(2):162-8. (*corresponding author, 2021 IF=38.637, Rank 4/94, infectious diseases)

10. Lin YT, Liu CJ, Chen TJ, Fung CP. Long-term mortality of patients with septic ocular or central nervous system complications from pyogenic liver abscess: A population-based study. PLoS ONE. 2012; 7(3):e33978. (2021 IF=3.752, Rank 29/73, multidisciplinary sciences)

11. Lin YT, Fung CP. Pyogenic liver abscess in the elderly: What we have learned? J Chin Med Assoc. 2012; 75(4):139-40. (2021 IF=3.396, Rank: 71/172, medicine, general & internal)

12. Wang YP, Liu CJ, Hu YW, Chen TJ, Lin YT*, Fung CP. Risk of cancer among patients with herpes zoster infection: a population-based study. CMAJ. 2012; 16;184(15):E804-9. (*corresponding author, 2021 IF=16.882, Rank 13/172, medicine, general & internal)

13. Tseng CP, Wu HS, Wu TH, Lin YT*, Fung CP. Clinical characteristics and outcome of patients with community-onset Klebsiella pneumoniae bacteremia requiring intensive care. J Microbiol Immunol Infect. 2013; 46(3):217-23. (*corresponding author, 2021 IF=10.273, Rank 17/136, microbiology)

14. Lin YT, Wang FD, Wu PF, Fung CP. Klebsiella pneumoniae liver abscess in diabetic patients: association of glycemic control with the clinical characteristics. BMC Infect Dis. 2013; 13:56. (2021 IF=3.670, Rank 60/94, infectious diseases)

15. Lin YT, Liu CJ, Yeh YC, Chen TJ, Fung CP. Ampicillin and amoxicillin use and the risk of Klebsiella pneumoniae liver abscess in Taiwan. J Infect Dis. 2013; 208(2): 211-7. (2021 IF=7.759, Rank: 19/94, Infectious Diseases)

16. Liu BH, Duh RW, Lin YT*, Yang TL, Fung CP, TSAR Hospitals. A multicenter surveillance of antimicrobial resistance in Serratia marcescens in Taiwan. J Microbiol Immunol Infect. 2014;47(5):387-93. (*corresponding author, 2021 IF=10.273, Rank 17/136, microbiology)

17. Lin YT, Wang FD, Chan YJ, Fu YC, Fung CP. Clinical and microbiological characteristics of tigecycline non-susceptible Klebsiella pneumoniae bacteremia in Taiwan. BMC Infect Dis. 2014; 14:1. (2021 IF=3.670, Rank 60/94, infectious diseases)

18. Lin YT, Tseng KY, Yeh YC, Yang FC, Fung CP, Chen NJ. TREM-1 promotes survival during Klebsiella pneumoniae liver abscess in mice. Infect Immun. 2014; 82(3):1335-42. (2021 IF=3.621, Rank 62/94, infectious diseases)

19. Lin YT, Huang YW, Liou RS, Chang YC, Yang TC. MacABCsm, an ABC-type tripartite efflux pump of Stenotrophomonas maltophilia involved in drug resistance, oxidative and envelope stress tolerances and biofilm formation. J Antimicrob Chemother. 2014; 69(12):3221-6. (2021 IF=5.758, Rank 54/279, Pharmacology & Pharmacy)

20. Lin YT*, Wang YP, Wang FD, Fung CP. Community-onset Klebsiella pneumoniae pneumonia in Taiwan: clinical features of the disease and associated microbiological characteristics of isolates from pneumonia and nasopharynx. Front Microbiol. 2015; 9:122. (*corresponding author, 2021 IF=6.064, Rank: 34/136, microbiology)

21. Chang YY, Chuang YC, Siu LK, Wu TL, Lin JC, Lu PL, Wang JT, Wang LS, Lin YT*, Huang LJ, Fung CP. Clinical features of patients with carbapenem nonsusceptible Klebsiella pneumoniae and Escherichia coli in intensive care units: A nationwide multicenter study in Taiwan. J Microbiol Immunol Infect. 2015 ;48(2):219-25. (*corresponding author, 2021 IF=10.273, Rank 17/136, microbiology)

22. Wu PF, Chang YY, Lin YT*, Wang FD, Chan YJ, Fung CP. Clinical characteristics and economic consequence of Klebsiella pneumoniae liver abscess in Taiwan. J Microbiol Immunol Infect. 2015; 48(2):190-7. (*corresponding author, 2021 IF=10.273, Rank 17/136, microbiology)

23. Wang YP, Liu CJ, Chen TJ, Lin YT*, Fung CP. Proton pump inhibitor use significantly increases the risk of cryptogenic liver abscess: a population-based study. Aliment Pharmacol Ther. 2015; 41(11):1175–81 (*corresponding author, 2021 IF=9.524, Rank: 17/279, pharmacology & pharmacy)

24. Lin YT, Huang YW, Chen SJ, Chang CW, Yang TC. SmeYZ Efflux Pump of Stenotrophomonas maltophilia Contributes to Drug Resistance, Virulence-related Characteristics, and Virulence in Mice. Antimicrob Agents Chemother. 2015; 59(7):4067-73. (2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

25. Lin YT, Pan YJ, Lin TL, Fung CP, Wang JT. Transfer of CMY-2 Cephalosporinase from Escherichia coli to virulent Klebsiella pneumoniae Causing a Recurrent Liver Abscess. Antimicrob Agents Chemother. 2015; 59(8):5000-2. (2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

26. Lin YT, Chuang C, Su CF, Chan YJ, Wang LS, Huang CT, Chuang YC, Siu LK, Fung CP. Efficacy of Appropriate Antimicrobial Therapy on the Survival of Patients with Carbapenem Nonsusceptible Klebsiella pneumoniae Infection: A Multicenter Study in Taiwan. Medicine. 2015; 94(33):e1405. (2021 IF=1.817, Rank: 134/329, medicine, general & internal)

27. Chiou YW, Lin YT*. Gas-forming Klebsiella pneumoniae liver abscess in a patient without diabetes. J Microbiol Immunol Infect. 2015; 48(6):709-10. (*corresponding author, 2021 IF=10.273, Rank 17/136, microbiology)

28. Lin YT*, Huang YW, Huang HH, Yang TC, Wang FD, Fung CP. In vivo evolution of tigecycline- non-susceptible Klebsiella pneumoniae strains in patients: relationship between virulence and resistance. Int J Antimicrob Agents. 2016; 48(5):485-491. (*corresponding author, 2021 IF=15.441, Rank 11/94, infectious diseases)

29. Juan CH, Huang YW, Lin YT*, Yang TC, Wang FD. Risk factors, Outcomes and Mechanisms of Tigecycline nonsusceptible Klebsiella pneumoniae Bacteremia. Antimicrob Agents Chemother. 2016; 60(12):7357-7363. (*corresponding author, 2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

30. Wu PF, Chuang C, Su CF, Lin YT*, Chan YJ, Wang FD, Chuang YC, Siu LK, Fung CP. High minimum inhibitory concentration of imipenem as a predictor of fatal outcome in patients with carbapenem non-susceptible Klebsiella pneumoniae. Sci Rep. 2016; 6:32665. (*corresponding author, 2021 IF=4.996, Rank: 19/73, multidisciplinary sciences)

31. Yang HS, Fang WL, Lin YT*. A case of liver abscess caused by tigecycline-nonsusceptible Klebsiella pneumoniae. J Microbiol Immunol Infect. 2016; 49(4):621-2. (*corresponding author, 2021 IF=10.273, Rank 17/136, microbiology)

32. Chuang C, Fan WC, Lin YT*, Wang FD. The emergence of Klebsiella pneumoniae liver abscess in non-diabetic patients and the distribution of capsular types. Gut Pathogens. 2016; 8:46. (*corresponding author, 2021 IF=5.324, Rank 44/136, microbiology)

33. Huang YC, Huang YW, Lin YT*, Wang FD, Chan YJ, Yang TC. Risk factors and outcome of levofloxacin-resistant Elizabethkingia meningoseptica bacteraemia in adult patients in Taiwan. Eur J Clin Microbiol Infect Dis. 2017; 36(8):1373-1380. (*corresponding author, 2021 IF=5.103, Rank 49/136, microbiology)

34. Lin YT. What can we learn from the dissemination of carbapenem-resistant Acinetobacter baumannii in patients with burn injury? J Chin Med Assoc. 2017; 80(4):189-190. (2021 IF=3.396, Rank: 71/172, medicine, general & internal)

35. Huang YC, Lin YT*, Wang FD. Comparison of the therapeutic efficacy of fluoroquinolone and non-fluoroquinolone treatment in patients with Elizabethkingia meningoseptica bacteraemia. Int J Antimicrob Agents. 2018; 51(1):47-51. (*corresponding author, 2021 IF=15.441, Rank 11/94, infectious diseases)

36. Su CF, Chuang C, Lin YT*, Chan YJ, Lin JC, Lu PL, Huang CT, Wang JT, Chuang YC, Siu LK, Fung CP. Treatment outcome of non-carbapenemase-producing carbapenem-resistant Klebsiella pneumoniae infections: a multicenter study in Taiwan. Eur J Clin Microbiol Infect Dis. 2018; 37(4):651-659. (*corresponding author, 2021 IF=5.103, Rank 49/136, microbiology)

37. Wu PF, Lin YT*, Wang FD, Yang TC, Fung CP. Is fluoroquinolone monotherapy a useful alternative treatment for Pseudomonas aeruginosa bacteraemia? Infection. 2018; 46(3):365-373 (*corresponding author, 2021 IF=7.455, Rank 21/94, infectious diseases)

38. Wu PS, Chuang C, Wu PF, Lin YT*, Wang FD. Anaerobic coverage as definitive therapy does not affect clinical outcomes in community-onset bacteremic biliary tract infection without anaerobic bacteremia. BMC Infect Dis. 2018; 18(1):277. (*corresponding author, 2021 IF=3.670, Rank 60/94, infectious diseases)

39. Huang YH, Chou SH, Liang SW, Ni CE, Lin YT*, Huang YW, Yang TC. Emergence of an XDR and carbapenemase-producing hypervirulent Klebsiella pneumoniae strain in Taiwan. J Antimicrob Chemother. 2018; 73(8):2039-2046. (*corresponding author, 2021 IF=5.758, Rank 54/279, Pharmacology & Pharmacy)

40. Lin YT*, Cheng YH, Juan CH, Wu PF, Huang YW, Chou SH, Yang TC, Wang FD. High mortality among patients infected with hypervirulent antimicrobial-resistant capsular type K1 Klebsiella pneumoniae strains in Taiwan. Int J Antimicrob Agents. 2018; 52(2):251-257. (*corresponding author, 2021 IF=15.441, Rank 11/94, infectious diseases)

41. Lin YT*, Su CF, Chuang C, Lin JC, Lu PL, Huang CT, Wang JT, Chuang YC, Siu LK, Fung CP. Appropriate Treatment for Bloodstream Infections Due to Carbapenem-Resistant Klebsiella pneumoniae and Escherichia coli: A Nationwide Multicenter Study in Taiwan. Open Forum Infect Dis. 2019; 6(2):ofy336. (*corresponding author, 2021 IF=4.423, Rank 61/136, microbiology)

42. Juan CH, Chuang C, Chen CH, Li L, Lin YT*. Clinical characteristics, antimicrobial resistance and capsular types of community-acquired, healthcare-associated, and nosocomial Klebsiella pneumoniae bacteremia. Antimicrob Resist Infect Control. 2019; 8:1. (*corresponding author, 2021 IF=6.459, Rank 38/210, Public, Environmental & Occupational Health)

43. Huang YC, Wu PF, Lin YT*, Wang FD. Comparison of clinical characteristics of bacteremia from Elizabethkingia meningoseptica and other carbapenem-resistant, non-fermenting Gram-negative bacilli at a tertiary medical center. J Microbiol Immunol Infect. 2019; 52(2):304-311. (*corresponding author, 2021 IF=10.273, Rank 17/136, microbiology)

44. Liao YT, Ko PS, Lin YT*. The first case of Klebsiella pneumoniae liver abscess with hemophagocytic lymphohistocytosis. J Microbiol Immunol Infect 2019; 52(2):363-364. (*corresponding author, 2021 IF=10.273, Rank 17/136, microbiology)

45. Juan CH, Fang SY, Chou CH, Tsai TY, Lin YT*. Clinical characteristics of patients with pneumonia caused by Klebsiella pneumoniae in Taiwan and prevalence of antimicrobial-resistant and hypervirulent strains: a retrospective study. Antimicrob Resist Infect Control. 2020; 9:4. (*corresponding author, 2021 IF=6.459, Rank 38/210, Public, Environmental & Occupational Health)

46. Cheng YH, Huang TW, Juan CH, Chou SH, Tseng YY, Chen TW, Yang TC, Lin YT*. Tigecycline-non-susceptible hypervirulent Klebsiella pneumoniae strains in Taiwan. J Antimicrob Chemother. 2020; 75(2):309-317. (*corresponding author, 2021 IF=5.758, Rank 54/279, Pharmacology & Pharmacy)

47. Lin YT*, Cheng YH, Chuang C, Chou SH, Liu WH, Huang CH, Yang TC, Kreiswirth BN, Chen L. Molecular and Clinical Characterization of Multidrug-Resistant and Hypervirulent Klebsiella pneumoniae Strains from Liver Abscess in Taiwan. Antimicrob Agents Chemother. 2020; 64(5):e00174-20. (*corresponding author, 2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

48. Chuang C, Chou SH, Wang FD, Huang YH, Tsai TH, Lin YT*. Fluoroquinolones as an alternative treatment for Klebsiella pneumoniae liver abscess and impact on hospital length of stay. Int J Antimicrob Agents. 2020 Oct;56(4):106120. (*corresponding author, 2021 IF=15.441, Rank 11/136, microbiology)

49. Chen KL, Wang SJ, Chuang C, Huang LY, Chiu FY, Wang FD, Lin YT*, Chen WM. Novel Design for Door Handle-A Potential Technology to Reduce Hand Contamination in the COVID-19 Pandemic. Am J Med. 2020; 133(11):1245-1246. (2021 IF=5.928, Rank: 36/172, medicine, general & internal)

50. Chuang C, Su CF, Lin JC, Lu PL, Huang CT, Wang JT, Chuang YC, Siu LK, Fung CP, Lin YT*. Does Antimicrobial Therapy Affect Mortality of Patients with Carbapenem-Resistant Klebsiella pneumoniae Bacteriuria? A Nationwide Multicenter Study in Taiwan. Microorganisms. 2020 Dec 19;8(12):2035. (*corresponding author, 2021 IF=4.926, Rank 67/157, microbiology)

51. Chen IR, Huang PH, Wu PF, Wang FD, Lin YT*. Clinical characteristics and outcomes of 56 patients with pneumonia caused by carbapenem-resistant Klebsiella pneumoniae. J Glob Antimicrob Resist. 2021 May 4;25:326-330. (*corresponding author, 2021 IF=4.349, Rank 100/279, pharmacology & pharmacy)

52. Huang PH, Cheng YH, Chen WY, Juan CH, Chou SH, Wang JT, Chuang C, Wang FD, Lin YT*. Risk factors and mechanisms of in vivo emergence of colistin resistance in carbapenem-resistant Klebsiella pneumoniae. Int J Antimicrob Agents. 2021 Jun;57(6):106342. (*corresponding author, 2021 IF=15.441, Rank 11/136, microbiology)

53. Cheng YH, Chou SH, Huang PH, Yang TC, Juan YF, Kreiswirth BN, Lin YT*, Chen L. Characterization of a mcr-1 and CRISPR-Cas System Co-harboring Plasmid in a Carbapenemase-Producing High-Risk ST11 Klebsiella pneumoniae Strain. Front Microbiol. 2021; 12:762947. (*corresponding author, 2021 IF=6.064, Rank: 34/136, microbiology)

54. Chen IR, Lin SN, Wu XN, Chou SH, Wang FD, Lin YT*. Clinical and Microbiological Characteristics of Bacteremic Pneumonia Caused by Klebsiella pneumoniae. Front Cell Infect Microbiol. 2022 Jun 23;12:903682. (*corresponding author, 2021 IF=6.073, Rank: 33/136, microbiology)

55. Huang PH, Chen WY, Chou SH, Wang FD, Lin YT*.Risk Factors for the Development of Colistin Resistance during Colistin Treatment of Carbapenem-Resistant Klebsiella pneumoniae Infections. Microbiol Spectr. 2022 Jun 29;10(3):e0038122. (*corresponding author, 2021 IF=9.043, Rank: 20/136, microbiology)

56. Juan CH, Chou SH, Chen IR, Yang CI, Lin YT*, Chen L. Intestinal colonisation with hypervirulent or third-generation cephalosporin-resistant Klebsiella pneumoniae strains upon hospital admission in a general ward in Taiwan. Int J Antimicrob Agents. 2022 Aug;60(2):106624. (*corresponding author, 2021 IF=15.441, Rank 11/136, microbiology)

 

其他共同作者

1. Jeng YY, Lin YT, Huang LJ, Huang LJ, Chen TL, Wang FD, Fung CP, Liu CY. Does Radiographic Evidence of Prior Pulmonary Tubercular Infection Influence the Choice of Empiric Antibiotics for Community-acquired Pneumonia in a Tuberculosis-endemic Area ? J Microbiol Immunol Infect. 2010; 43(5):386-94. (2021 IF=10.273, Rank 17/136, microbiology)

2. Hsu SF, Lin YT, Chen TL, Siu LK, Hsueh PR, Huang ST, Fung CP. Antimicrobial resistance of Moraxella catarrhalis isolates in Taiwan. J Microbiol Immunol Infect. 2012; 45(2):134-40. (2021 IF=10.273, Rank 17/136, microbiology)

3. Fung CP, Chang FY, Lin JC, Ho DM, Chen CT, Chen JH, Yeh KM, Chen TL, Lin YT, Siu LK. Immune response and pathophysiological features of Klebsiella pneumoniae liver abscesses in an animal model. Lab Invest. 2011; 91(7):1029-39. (2021 IF=5.515, Rank 16/77, pathology)

4. Wang FD, Chen YY, Chen TL, Lin YT, Fung CP. Risk factors and mortality of nosocomial infections of methicillin-resistant Staphylococcus aureus in an intensive care unit. J Crit Care. 2011; 26:82-8. (2021 IF=4.298, Rank 13/35, critical care medicine)

5. Fung CP, Lin YT, Lin JC, Chen TL, Yeh KM, Chang FY, Chuang HC, Wu HS, Tseng CP, Siu LK. Klebsiella pneumoniae in Gastrointestinal Tract and Pyogenic Liver Abscess. Emerg Infect Dis. 2012; 18(8):1322-5. (2021 IF=16.126, Rank 9/94, infectious diseases)

6. Lee YT, Kuo SC, Yang SP, Lin YT, Tseng FC, Chen TL, Fung CP. Impact of Appropriate Antimicrobial Therapy on Mortality Associated With Acinetobacter baumannii Bacteremia: Relation to Severity of Infection. Clin Infect Dis. 2012; 55(2):209-15. (2021 IF=20.999, Rank 6/94, infectious diseases)

7. Ou SM, Liu CJ, Teng CJ, Lin YT, Chang YS, Chiang SC, Tzeng CH, Chen TJ. Impact of pulmonary and extrapulmonary tuberculosis infection in kidney transplantation: a nationwide population-based study in Taiwan. Transpl Infect Dis. 2012; 14(5):502-9. (2020 IF=2.228 Rank 17/25, transplantation)

8. Cheng A, Fung CP, Liu CC, Lin YT, Tsai HY, Chang SC, Chou AH, Chang JY, Jiang RH, Hsieh YC, Su IJ, Chong PC, Hsieh SM.A Phase I, randomized, open-label study to evaluate the safety and immunogenicity of an enterovirus 71 vaccine. Vaccine. 2013; 31(20):2471-6. (2021 IF=4.169 Rank 71/195, medicine, research & experimental)

9. Wu HS, Kuo SC, Chen LY, Chiang MC, Lin YT, Wang FD, Fung CP. Comparison between patients under hemodialysis with community-onset bacteremia caused by community-associated and healthcare-associated methicillin-resistant Staphylococcus aureus strains. J Microbiol Immunol Infect. 2013; 46(2):96-103. (2021 IF=10.273, Rank 17/136, microbiology)

10. Kuo SC, Lee YT, Yang SP, Chiang MC, Lin YT, Tseng FC, Chen TL, Fung CP. Evaluation of the effect of appropriate antimicrobial therapy on mortality associated with Acinetobacter nosocomialis bacteraemia. Clin Microbiol Infect. 2013; 19(7):634-9. (2021 IF=13.310, Rank 12/94, infectious diseases)

11. Wang FD, Liao CH, Lin YT, Sheng WH, Hsueh PR. Trends in the susceptibility of commonly encountered clinically significant anaerobes and susceptibilities of blood isolates of anaerobes to 16 antimicrobial agents, including fidaxomicin and rifaximin, 2008-2012, northern Taiwan. Eur J Clin Microbiol Infect Dis. 2014; 33(11):2041-52. (2021 IF=5.103, Rank 49/136, microbiology)

12. Lin TL, Chuang YP, Huang YT, Hsieh PF, Lin YT, Wang JT. Identification of an immuno-dominant protein from Klebsiella pneumoniae strains causing pyogenic liver abscess: implication in serodiagnosis. BMC Microbiol. 2014; 14:321. (2021 IF=4.465, Rank 60/136, microbiology)

13. Huang YW, Liou RS, Lin YT, Huang HH, Yang TC. A Linkage between SmeIJK Efflux Pump, Cell Envelope Integrity, and σE-Mediated Envelope Stress Response in Stenotrophomonas maltophilia. PLoS One. 2014; 9(11):e111784. (2021 IF=3.752, Rank 29/73, multidisciplinary sciences)

14. Pan YJ, Lin TL, Lin YT, Su PA, Chen CT, Hsieh PF, Hsu CR, Chen CC, Hsieh YC, Wang JT. Identification of Capsular Types in Carbapenem-Resistant Klebsiella pneumoniae Strains by wzc Sequencing and Implications for Capsule Depolymerase Treatment. Antimicrob Agents Chemother. 2015; 59(2):1038-47. (2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

15. Huang YW, Hu RM, Lin YT, Huang HH, Yang TC. The Contribution of Class 1 Integron to Antimicrobial Resistance in Stenotrophomonas maltophilia. Microb Drug Resist. 2015; 21(1):90-6. (2021 IF=2.706, Rank: 105/136, microbiology)

16. Cheng YH, Lin TL, Pan YJ, Wang YP, Lin YT, Wang JT. Colistin Resistance Mechanisms in Klebsiella pneumoniae Strains from Taiwan. Antimicrob Agents Chemother. 2015; 59(5):2909-13. (2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

17. Huang YW, Wu CJ, Hu RM, Lin YT, Yang TC. Interplay among membrane-bound lytic transglycosylase D1, the CreBC two-component regulatory system, the AmpNG-AmpDI-NagZ-AmpR regulatory circuit, and L1/L2 β-lactamase expression in Stenotrophomonas maltophilia. Antimicrob Agents Chemother. 2015; 59(11):6866-72. (2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

18. Huang HH, Lin YT, Chen WC, Huang YW, Chen SJ, Yang TC. Expression and Functions of CreD, an Inner Membrane Protein in Stenotrophomonas maltophilia. PLoS One. 2015; 10(12):e0145009. (2021 IF=3.752, Rank 29/73, multidisciplinary sciences)

19. Wu CJ, Huang YW, Lin YT, Yang TC. Inactivation of Lytic Transglycosylases Increases Susceptibility to Aminoglycosides and Macrolides by Altering the Outer Membrane Permeability of Stenotrophomonas maltophilia. Antimicrob Agents Chemother. 2016; 60(5):3236-9. (2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

20. Cheng YH, Lin TL, Lin YT, Wang JT. Amino Acid Substitutions of CrrB Responsible for Resistance to Colistin through CrrC in Klebsiella pneumoniae. Antimicrob Agents Chemother. 2016; 60(6):3709-16. (2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

21. Wu CJ, Huang YW, Lin YT, Ning HC, Yang TC. Inactivation of SmeSyRy Two-Component Regulatory System Inversely Regulates the Expression of SmeYZ and SmeDEF Efflux Pumps in Stenotrophomonas maltophilia. PLoS One. 2016; 11(8):e0160943. (2021 IF=3.752, Rank 29/73, multidisciplinary sciences)

22. Chiu SK Chan MC, Huang LY, Lin YT, Lin JC, Lu PL, Siu LK, Chang FY, Yeh KM. Tigecycline resistance among carbapenem-resistant Klebsiella Pneumoniae: Clinical characteristics and expression levels of efflux pump genes. PLoS One. 2017; 12(4):e0175140. (2021 IF=3.752, Rank 29/73, multidisciplinary sciences)

23. Pan YJ, Lin TL, Chen CC, Tsai YT, Cheng YH, Chen YY, Hsieh PF, Lin YT, Wang JT. Klebsiella Phage ΦK64-1 Encodes Multiple Depolymerases for Multiple Host Capsular Types. J Virol. 2017; 91(6):e02457-16. (2021 IF=6.549, Rank 11/37, virology)

24. Huang HH, Chen WC, Lin CW, Lin YT, Ning HC, Chang YC, Yang TC. Relationship of the CreBC two-component regulatory system and inner membrane protein CreD with swimming motility in Stenotrophomonas maltophilia. PLoS One. 2017; 12(4):e0174704. (2021 IF=3.752, Rank 29/73, multidisciplinary sciences)

25. Huang YW, Lin CW, Ning HC, Lin YT, Chang YC, Yang TC. Overexpression of SmeDEF Efflux Pump Decreases Aminoglycoside Resistance in Stenotrophomonas maltophilia. Antimicrob Agents Chemother. 2017; 61(5):e02685-16. (2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

26. Huang YW, Wang Y, Lin Y, Lin C, Lin YT, Hsu CC, Yang TC. Impacts of Penicillin Binding Protein 2 Inactivation on β-Lactamase Expression and Muropeptide Profile in Stenotrophomonas maltophilia. mSystems. 2017; 2(4):e00077-17. (2021 IF=7.331, Rank: 27/136, microbiology)

27. Wu CJ, Chiu TT, Lin YT, Huang YW, Li LH, Yang TC*. Role of smeU1VWU2X Operon in Alleviation of Oxidative Stresses and Occurrence of Sulfamethoxazole-Trimethoprim-Resistant Mutants in Stenotrophomonas maltophilia. Antimicrob Agents Chemother. 2018; 62(2):e02114-17. (2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

28. Chiu SK, Ma L, Chan MC, Lin YT, Fung CP, Wu TL, Chuang YC, Lu PL, Wang JT, Lin JC, Yeh KM. Carbapenem Nonsusceptible Klebsiella pneumoniae in Taiwan: Dissemination and Increasing Resistance of Carbapenemase Producers During 2012-2015. Sci Rep. 2018; 8(1):8468. (2021 IF=4.996, Rank: 19/73, multidisciplinary sciences)

29. Cheng YH, Lin TL, Lin YT, Wang JT*. A putative RND-type efflux pump, H239_3064, contributes to colistin resistance through CrrB in Klebsiella pneumoniae. J Antimicrob Chemother. 2018; 73(6):1509-1516. (*corresponding author, 2021 IF=5.758, Rank 54/279, Pharmacology & Pharmacy)

30. Huang HH, Lin YT, Chen PY, Li LH, Ning HC, Yang TC*. ClpA and HtpX Proteases Are Involved in Intrinsic Aminoglycoside Resistance of Stenotrophomonas maltophilia and Are Potential Aminoglycoside Adjuvant Targets. Antimicrob Agents Chemother. 2018; 62(8):e00554-18. (2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

31. Huang HH, Chen PY, Hu RM, Lin YT, Li LH, Yang TC. Impacts of L1 Promoter Variation and L2 Clavulanate Susceptibility on Ticarcillin-Clavulanate Susceptibility of Stenotrophomonas maltophilia. Antimicrob Agents Chemother. 2018; 62(11):e01222-18. (2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

32. Wang CH, Lu PL, Liu EY, Chen YY, Lin FM, Lin YT, Chang FY, Lin JC. Rapid identification of capsular serotype K1/K2 Klebsiella pneumoniae in pus samples from liver abscess patients and positive blood culture samples from bacteremia cases via an immunochromatographic strip assay. Gut Pathog. 2019; 11:11. (2021 IF=5.324, Rank 44/136, microbiology)

33. Lee KC, Chen P, Maricic I, Inamine T, Hu J, Gong S, Sun JC, Dasgupta S, Lin HC, Lin YT, Loomba R, Stärkel P, Kumar V, Schnabl B. Intestinal iNKT cells migrate to liver and contribute to hepatocyte apoptosis during alcoholic liver disease. Am J Physiol Gastrointest Liver Physiol. 2019; 316(5):G585-G597. (2021 IF=4.889, Rank 19/81, physiology)

34. Pan YJ, Lin TL, Chen YY, Lai PH, Tsai YT, Hsu CR, Hsieh PF, Lin YT, Wang JT. Identification of three podoviruses infecting Klebsiella encoding capsule depolymerases that digest specific capsular types. Microb Biotechnol. 2019; 12(3):472-486. (2021 IF=6.575, Rank 29/136, microbiology)

35. Huang YW, Huang HH, Huang KH, Chen WC, Lin YT, Hsu CC, Yang TC. AmpI Functions as an Iron Exporter To Alleviate β-Lactam-Mediated Reactive Oxygen Species Stress in Stenotrophomonas maltophilia. Antimicrob Agents Chemother 2019; 63(4):e02467-18. (2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

36. Wu CJ, Lu HF, Lin YT, Zhang MS, Li LH, Yang TC. Substantial Contribution of SmeDEF, SmeVWX, SmQnr, and Heat Shock Response to Fluoroquinolone Resistance in Clinical Isolates of Stenotrophomonas maltophilia. Front Microbiol. 2019; 10:822. (2021 IF=6.064, Rank: 34/136, microbiology)

37. Li LH, Zhang MS, Wu CJ, Lin YT, Yang TC. Overexpression of SmeGH contributes to the acquired MDR of Stenotrophomonas maltophilia. J Antimicrob Chemother. 2019; 74(8):2225-2229. (2021 IF=5.758, Rank 54/279, Pharmacology & Pharmacy)

38. Wu PS, Chou CK, Hsieh YC, Chen CK, Lin YT, Huang YH, Hou MC, Lin HC, Lee KC. Antibiotic use in patients with acute cholecystitis after percutaneous cholecystostomy. J Chin Med Assoc. 2020; 83(2):134-140. (2021 IF=3.396, Rank: 71/172, medicine, general & internal)

39. Tu YF, Chien CS, Yarmishyn AA, Lin YY, Luo YH, Lin YT, Lai WY, Yang DM, Chou SJ, Yang YP, Wang ML, Chiou SH. A Review of SARS-CoV-2 and the Ongoing Clinical Trials. Int J Mol Sci. 2020; 21(7):2657. (2021 IF=6.208 Rank: 69/296, biochemistry & molecular biology)

40. Wang CH, Siu LK, Chang FY, Tsai YK, Lin YT, Chiu SK, Huang LY, Lin JC. A Novel Deletion Mutation in pmrB Contributes to Concurrent Colistin Resistance in Carbapenem-Resistant Escherichia coli Sequence Type 405 of Clinical Origin. Antimicrob Agents Chemother. 2020; 64(6):e00220-20. (2021 IF=5.938, Rank 51/276, pharmacology & pharmacy)

41. Liang Y, Wang ML, Chien CS, Yarmishyn AA, Yang YP, Lai WY, Luo YH, Lin YT, Chen YJ, Chang PC, Chiou SH. Highlight of Immune Pathogenic Response and Hematopathologic Effect in SARS-CoV, MERS-CoV, and SARS-Cov-2 Infection. Front Immunol. 2020; 11:1022. (2021 IF=8.786, Rank: 33/161, immunology)

42. Choi M, Hegerle N, Nkeze J, Sen S, Jamindar S, Nasrin S, Sen S, Permala-Booth J, Sinclair J, Tapia MD, Johnson JK, Mamadou S, Thaden JT, Fowler VG Jr, Aguilar A, Terán E, Decre D, Morel F, Krogfelt KA, Brauner A, Protonotariou E, Christaki E, Shindo Y, Lin YT, Kwa AL, Shakoor S, Singh-Moodley A, Perovic O, Jacobs J, Lunguya O, Simon R, Cross AS, Tennant SM. The Diversity of Lipopolysaccharide (O) and Capsular Polysaccharide (K) Antigens of Invasive Klebsiella pneumoniae in a Multi-Country Collection. Front Microbiol. 2020; 11:1249. (2021 IF=6.064, Rank: 34/136, microbiology)

43. Li LH, Wu CM, Lin YT, Pan SY, Yang TC. Roles of FadRACB system in formaldehyde detoxification, oxidative stress alleviation and antibiotic susceptibility in Stenotrophomonas maltophilia. J Antimicrob Chemother. 2020; 75(8):2101-2109. (2021 IF=5.758, Rank 54/279, Pharmacology & Pharmacy)

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