陳明德醫師   Ming-Teh Chen, M.D., Ph.D.

學位：

臺北醫學大學醫學系醫學士

國防大學國防醫學院醫學科學研究所博士

現職：

臺北榮民總醫院教學部 資深顧問

臺北榮民總醫院神經醫學中心神經外科 特約醫師

教職：

國立陽明交通大學醫學院醫學系外科學科兼任副教授

國防醫學院醫學系外科學科兼任臨床教授

教育部部定副教授

經歷：

臺北榮民總醫院教學部教師培育科 主任

臺北榮民總醫院神經醫學中心神經外科 主治醫師

臺北榮民總醫院神經醫學中心神經重症加護科 主任

美國加州大學洛杉磯分校(UCLA)神經外科 研究員

美國國家衛生研究院(NIH)藥物濫用研究所(NIDA) 研究員

專長學科：

顱底手術、腦瘤手術、脊椎手術、神經重症、腦瘤分子生物學研究、神經電生理研究

通訊處：

台北市石牌路二段201號臺北榮民總醫院神經外科

E-mail：

mtchen@vghtpe.gov.tw

近年著作：

1. Ping-Hsing Tsai, Yun-Ching Chang, Yi-Yen Lee, Yu-Ling Ko, Yu-Hsuan Yang,Chun-Fu Lin, Yuh-Lih Chang, Wen-Chung Yu, Yang-Hsin Shih, Ming-Teh Chen. Differentiation of blood T cells: Reprogramming human induced pluripotent stem cells into neuronal cells. Journal of the Chinese Medical Association 78 (2015) 353-359
2. Wei-Hsiu Liu, Ming-Teh Chen, Mong-Lien Wang, Yi-Yen Lee, Guang-Yuh Chiou, Chian-Shiu Chien, Pin-I Huang, Yi-Wei Chen, Ming-Chao Huang, Shih-Hwa Chiou, Yang-Hsin Shih, Hsin-I Ma. Cisplatin-selected resistance is associated with increased motility and stem-like properties via activation of STAT3/Snail axis in atypical teratoid/rhabdoid tumor cells. Oncotarget. 2015 Jan 30;6(3):1750-68
3. Ping-Hsing Tsai, Yun-Ching Chang, Yi-Yen Lee, Yu-Ling Ko, Yu-Hsuan Yang, Chun-Fu Lin, Yuh-Lih Chang, Wen-Chung Yu, Yang-Hsin Shih, Ming-Teh Chen. Differentiation of blood T cells: Reprogramming human induced pluripotent stem cells into neuronal cells. Journal of the Chinese Medical Association. 2015 Jun;78(6):353-9
4. Yi-Yen Lee, Yi-Ping Yang, Pin-I Huang, Wen-Cheng Lie, Ming-Chao Huang,  Chung-Lan Kao, Yann-Jang Chen, Ming-Teh Chen. Exercise suppresses COX-2 pro-inflammatory pathway in vestibular migraine. Brain Research Bulletin. 2015 Jul;116:98-105
5. Lu-Jen Chen, I-Chun Lai, Tai-Tong Wong, Shih-Chieh Lin, Donald Ming-Tak Ho, Wan-Yuo Guo, Sang-Hue Yen, Kai-Ping Chang, Ming-Teh Chen, Yi-Wei Chen. Can mixed pure hepatocellular carcinoma and germinoma arise together in the brain? Journal of the Chinese Medical Association. 2015 Sep; 78(9):562-6
6. Wei-Hsin Wang, Cheng-Chia Lee, Huai-Che Yang, Kang-Du Liu, Hsiu-Mei Wu, Cheng-Ying Shiau, Wang-You Guo, David Hung-Chi Pan, Wen-Yuh Chung, Ming-Teh Chen. Gamma knife radiosurgery for atypical and anaplastic meningioma. World Neurosurgery. 2016 Mar; 87:557-64
7. Hsiao-Yun Chen, Liang-Ting Lin, Mong-Lien Wang, Shu-Hsien Lee,, Ming- Long Tsai1, Chi-Chang Tsai, Wei-Hsiu Liu, Tzu-Chien Chen, Yi-Ping Yang, Yi- Yen Lee, Yuh-Lih Chang, Pin-I Huang, Yi-Wei Chen, Wen-Liang Lo, Shih- Hwa Chiou, Ming-Teh Chen. Musashi-1 regulates AKT-derived IL-6 a autocrinal/paracrinal malignancy and chemoresistance in glioblastoma. Oncotarget, 2016 Jul 5;7(27):42485-42501
8. Wen-Shin Song, Yi-Ping Yang, Chi-Shuan Huang,  Kai-Hsi Lu, Wei-Hsiu Liu, Wei-Hwa Wu, Sheua-Dong lee, Yi-Wei Chen, Pin-I Huang, Ming-Teh Chen. Sox2, stemness gene, regulated tumor-initiating and drug-resistant property in CD133-positive glioma stem cells. Journal of the Chinese Medical Association 2016 Oct;79(10):538-45
9. Tzu-Wei Lin, Ming-Teh Chen, Liang-Tin Lin, Pin-I Huang, Wen-Liang Lo, Yi-Ping Yang, Kai-Hsi Lu, Yi-Wei Chen, Shih-Hwa Chiou, Cheng-Wen Wu. TDP-43/HDAC6 axis promoted tumor progression and regulated nutrient deprivation-induced autophagy in glioblastoma. Oncotarget. 2017 May 18;8(34):56612-56625
10. Hsiao-Yun Chen, Liang-Ting Lin, Mong-Lien Wang, Kun-Ling Tsai, Pin-I Huang, Yi-Ping Yang, Yi-Yen Lee, Yi-Wei Chen, Wen-Liang Lo, Yuan-Tzu Lan, Shih-Hwa Chiou, Chien-Min Lin, Hsin-I Ma, Ming-Teh Chen. Musashi-1 promotes chemoresistant granule formation by PKR/eIF2α signalling cascade in refractory glioblastoma. Biochim Biophys Acta. 2018 May;1864(5 Pt A):1850-1861
11. Yi-Yen Lee, Aliaksandr A Yarmishyn, Mong-Lien Wang, Hsiao-Yun Chen, Shih-Hwa Chiou, Yi-Ping Yang, Chun-Fu Lin, Pin-I Huang, Yi-Wei Chen, Hsin-I Ma, Ming-Teh Chen. MicroRNA-142-3p is involved in regulation of MGMT expression in glioblastoma cells. Cancer Management and Research. 2018 Apr 12;10:775-785
12. Yi-Ping Yang, Phan Nguyen Nhi Nguyen, Hsin-I Ma, Wen-Jin Ho, Yi-Wei Chen, Yueh Chien, Aliaksandr A. Yarmishyn, Pin-I Huang, Wen-Liang Lo, Chien-Ying Wang, Yung-Yang Liu , Yi-Yen Lee, Chien-Min Lin, Ming-Teh Chen, Mong-Lien Wang. Tumor mesenchymal stromal cells regulate cell migration of atypical teratoid rhabdoid tumor through exosome-mediated miR155/SMARCA4 pathway. Cancers (Basel). 2019 May 24;11(5)