楊盈盈醫師   Ying Ying Yang, M.D., Ph.D., DrPH.

學位：

國立陽明大學公共衛生硏究所博士

國立陽明大學臨床醫學研究所博士

國立陽明大學醫學士

現職：

臺北榮民總醫院教學部主任&醫療創新中心執行秘書

國立陽明交通大學醫學系副系主任

陽明交通大學醫學系內科學科專任教授&臨床醫學研究所合聘教授

臺北榮民總醫院內科部胃腸科及一般內科兼任主治醫師

考選部 醫學臨床技能測驗試務委員會委員

臺灣醫學教育學會理事及電子報編輯小組召集人、醫學教育雜誌會編輯委員，輔導辦理OSCE工作委員、陽明交通大學試務主持人及北榮OSCE考場主任，EPA評量系統建置規劃小組委員

台灣擬真醫學教育學會理事長

內科醫學會 住院醫師里程碑小組委員

衛生福利部輔導臨床技能評估模式及一般醫學臨床教師培育計畫北榮「一般醫學內科訓練示範中心」執行長

陽明大學醫學院院務會代表、醫學系 教學發展委員會

台灣肝臟研究學會NAFLD/NASH/MAFLD SIG on Basic Research負責人

2022 APASL Annual Meeting&2024 STC on MAFLD  學術委員

曾任台北市醫師公會會員大會代表

教職：

國立陽明交通大學醫學系內科學科專任教授

國立陽明交通大學臨床醫學研究所合聘教授

經歷：

全國公私立醫學校院院長會議「新制醫學系工作小組」委員

台北市醫師公會會員大會代表

臺北榮民總醫院內科部一般內科主治醫師

臺北榮民總醫院內科部胃腸科主治醫師

台北市立忠孝醫院內科主治醫師

臺北榮民總醫院內科部胃腸科總醫師

臺北榮民總醫院內科部住院醫師

加拿大卡加利大學肝病中心博士後進修

專長學科：

代謝相關性脂肪肝病，肝硬化，門脈高壓症，慢性肝臟疾病，醫學/醫事/擬真/元宇宙教育，獲2023 Harvard Medical School, Training to teach postgraduate program, 高教認證教師

專科證書：

中華民國內科專科醫師

中華民國醫師消化系專科醫師

中華民國醫師消化系內視鏡專科醫師

專科學會：

台灣內科醫學會

台灣消化系內視鏡醫學會

中華民國消化系醫學會

中華民國醫師超音波醫學會

台灣靜脈暨腸道營養醫學會

通訊處：

台北市石牌路二段201號臺北榮民總醫院教學部

E-mail：

yangyy@vghtpe.gov.tw

獲獎紀錄：

民國100年 財團法人肝病防治學術基金會肝病防治優秀論文獎

民國101年 行政院國家科學委員會吳大猷先生紀念獎、臺灣肝臟研究學會優秀論文獎、林榮耀教授學術教育基金會優秀論文獎

民國102年 中研院年輕學者研究著作獎

107年度銓敘部三等人事獎章

109年度 台北市醫師公會第二十八屆醫師杏林獎

108年度 國軍退除役官兵輔導委員會醫療及安養機構優良醫師

107-113年度財團法人醫療品質策進會國家品質獎擬真情境類新人組金、銀、特優獎，NHQA智慧醫療類智慧醫療解決方案組標章

民國100-112年台灣醫學教育委員會『一般醫學師資培育教學影片』全國比賽金、銀、銅牌及佳作、學會年會最佳壁報獎

曾獲臺北榮民總醫院臨床教學績優醫師獎、台北榮總醫師創新(改良)獎/創新(改良)獎，實習醫學生票選最佳教學醫師、優良醫師「醫師學術論文獎」，CiC創新研討會銀獎

國立陽明大學醫學生網路課程教學評鑑票選優良教師、國立陽明大學醫學院優良教師及教學優良獎座、國立陽明大學教師學術卓越獎 [2017-2018&2019-2023]

106-113年度台灣擬真醫學教育學會優秀論文獎、擬真醫學應用及教案影片特優及優等獎

醫學教育代表著作

1. Shiau‑Shian Huang#, Chao-Chung Ho, Yeong-Ruey Chu, Jr-Wei Wu & Ying-Ying Yang. The quantified analysis of the correlation between medical humanities curriculums and medical students’ performance. BMC Medical Education , 2023 Aug 11;23(1):571.
2. Shiau-Shian Huang, Yu-Fan Lin, Anna YuQing Huang, Ji-Yang Lin, Ying-Ying Yang,* Sheng-Min Lin, Wen-Yu Lin, Pin-Hsiang Huang, Tzu-Yao Chen, Stephen J.H. Yang,* Jiing-Feng Lirng, and Chen-Huan Chen. Using machine learning to identify key subject categories predicting the pre-clerkship and clerkship performance: 8-year cohort study. JCMA 2023, 12, September (accepted).
3. Chia-Chang Huang, Ching-Jung Chung, Yi-Ting, Wu, Po-Ting Hsu, Jen-Feng Liang, Ying-Ying Yang*, Jie Chi Yang*. A five-year department-based electronic usage data analysis on electronic journal access, library training courses, and scholarly publications. Electronic Library 42 No. 1, 2024, pp. 23-36.
4. Ching-Jung Chung, Yen-Hsun Huang, Jie Chi Yang*, Ying-Ying Yang, Shiau-Shian Huang, Sheng-Min Lin, Jiing-Feng Lirng, Tzu-Hao Li, Chen-Huan Chen, and Yung-Yang Lin. The dissemination of holistic health care and evidence-based medicine courses from institution-based to department-based via a course management system. Interactive Learning Environments2023, March, accepted (IF:4.965). DOI: 10.1080/10494820.2023.2194932..
5. Pin-Hsuan Wang, Anna YuQing Huang, Yen-Hsun, Huang, Ying-Ying Yang*, Jiing-Feng Lirng, Tzu-Hao Li, Ming-Chih Hou, Chen-Huan Chen, Albert ChihChieh Yang, Chi-Hung Lin, Wayne Huey-Herng Sheu. Feasibility and Accessibility of Human-centered AI-based Simulation System for Improving the Occupational Safety of Clinical Workplace. Educational Technology & Society,  2023; 26 (1).
6. JF Liang, HM Cheng, CC Huang, YY Yang and CH Chen. Lessons Learned from a Novel Three-year Longitudinal Stepwise “Residents-as-Teachers” Program.”. JCMA 2023;86(6):577-583.
7. Yu-Fan Lin, Chen-Huan Chen,* Ying-Ying Yang,* Nai-Rong Kuo, Tzu-Hao Li, Jiing-Feng Lirng, Ming-Chih Hou, Wayne Huey-Herng Sheu.. A single-center cross-sectional study of cross-professional faculty’s perception of virtual classes under different scenarios: A stepwise approach. JCMA 2022;85(7):759-766.
8. Yen-Po Tsao, Wan-Yu Yeh, Teh-Fu Hsu, Lok-Hi Chow, Wei-Chih Chen, Ying-Ying Yang, Boaz Shulruf, Chen-Huan Chen & Hao-Min Cheng. Implementing a fipped classroom model in an evidence-based medicine curriculum for pre-clinical medical students: evaluating learning efectiveness through prospective propensity score-matched cohorts. BMC Medical Education 2022;22(1):185 (SCI).
9. Jen-Feng Liang, Teh-Fu Hsu, Chien-Yu Chen, Chih-Wei Yang, Wei-Horng Jean, Liang-Shiou Ou, Hao-Min Cheng, Chia-Chang Huang, Ying-Ying Yang, Chen-Huan Chen. Developing a competency-based framework for resident-as-teacher. J Formos Med Assoc 2022;S0929-6646(22)00047-X (SCI).
10. Dung-Hung Chiang, Chia-Chang Huang, Shu-Chuan Cheng, Jui-Chun Cheng, Cheng-Hsien Wu, Shiau-Shian Huang, Ying-Ying Yang*, Ling-Yu Yang, Shou-Yen Kao, Chen-Huan Chen, Boaz Shulruf, Fa-Yauh Lee. Immersive virtual reality (VR) trainings increase the self-efficacy of in-hospital healthcare providers and patient families about tracheostomy-related knowledge and care skills: a prospective pre-post study. Medicine 2022;101(2):e28570 (SCI).
11. Chiang DH, Chen CT, Wang TY, Yang YY*, Huang CC, Li TH, Huang SS, Kao SY, Chen CH, Hou MC, Sheu WHH. Enhancing the learning and transfer of preprocedural communication skills during clerkship using audio-visual material: a prospective case-controlled study over two years. BMJ Open. 2022 Jan 5;12(1):e055953(SCI).
12. Jr-Wei Wu, Hao-Min Cheng, Shiau-Shian Huang, Jen-Feng Liang, Chia-Chang Huang, Boaz Shulruf, Ying-Ying Yang,* Chen-Huan Chen,* Ming-Chih Hou, Wayne Huey-Herng Sheu. Medical school grades may predict future clinical competence. J Chin Med Assoc 2022;85(9):909-914(SCI).
13. Wu JW, Cheng HM, Huang SS, Liang JF, Huang CC, Yang LY, Shulruf B, Yang YY*, Chen CH, Hou MC, Sheu WHH. Comparison of OSCE Performance Between 6- and 7-Year Medical School Curricula in Taiwan. BMC Med Educ. 2022 Jan 4;22(1):15 (SCI).
14. Yen-Po Tsao , Wan-Yu Yeh , Teh-Fu Hsu , Lok-Hi Chow , Wei-Chih Chen , Ying-Ying Yang, Boaz Shulruf , Chen-Huan Chen, Hao-Min Cheng*.. Implementing a flipped classroom model in an evidence-based medicine curriculum for pre-clinical medical students: evaluating learning effectiveness through prospective propensity score-matched cohorts. BMC Med Educ 2022 Mar 16;22(1):185.
15. Chao-Chung Ho, Yeong-Ruey Chu, Jr-Wei Wu, Shiau‑Shian Huang, Ying-Ying Yang. The quantified analysis of the impact of medical humanities courses on medical student’s performance. BMC Med Educ 2023, Feb (accepted).
16. Chang CC,  Huang HC,  Lee WS,  Chuang CL,  Huang LJ,  Lu DY,  Yang YY,  Hsu HC. Early clinical exposure improves medical students' recognition of the need for professionalism and inter-professional collaboration. JCMA 2021 Aug 1;84(8):778-782 (SCI).
17. Chang SL, Kuo MJ, Lin YJ, Chen SA, Yang YY*, Cheng HM, Yang LY, Kao SY, Lee FY.. Virtual reality (VR) informative aids increase residents' atrial fibrillation (AF) ablation procedures-related knowledge and patients' satisfaction. J Chin Med Assoc 2021, 84(1):25-32(SCI).
18. Shih-Lin Chang, Ming-Jen Kuo, Yenn-Jiang Lin , Shih-Ann Chen , Chung-Ting Chen, Ying-Ying Yang*, Ling-Yu Yang, Shou-Yen Kao , Boaz Shulruf , Fa-Yauh Lee . Virtual reality-based preprocedural education increases preparedness and satisfaction of patients about the catheter ablation of atrial fibrillation. JCMA 2021;84(7):690-697(SCI).
19. Shulruf B, Yang YY*, Huang PH, Yang LY , Huang CC, Huang CC, Liu CW, Huang SS, Chen CH, Lee FY, Kao SY: Standard Setting Made Easy: Validating the Equal Z-score (EZ) method for setting cut-score for clinical examinations. BMC Med Educ. 2020;20:167. (SCI).
20. Lee FY, Yang YY*, Huang CC, Huang LJ, Chang CC, Liang JF, Huang SS, Lee WS, Lu DY, Chuang CL, Yang LY, Huang HC, Shulruf B, Chen CH, Kao SY. Sustained effects of training modules for leaders among clinical instructors for core competences promotion in Taiwan: a 4-year explanatory case study. BMC Med Educ. 2020; 20:155 (SCI).
21. Shiao TH, Yang YY*, Wu CY, Yang LY, Hwang SJ, Huang CC, Liang JF, Kao SY, Lee FY. Creation of nurse-specific integrated inter-professional collaboration and team-efficiency (IIT) scenario/video improves trainees' attitudes and performances. JCMA 2019 Jul;82(7):546-553 (SCI).
22. Su CJ, Pan SW, Huang LJ, Yang LY, Yang YY*, Hwang SJ, Chuang CL, Chang CC, Huang HC, Kao SY, Lee FY. Trios-OSCE-based simulation course enhances the sub-competency of Emergency-Stabilization for postgraduate year-1 residents. JCMA 2019; May;82(5):407-412 (SCI).
23. Huang CC, Hsu HC, Yang LY, Chen CH, Yang YY*, Chang CC, Chuang CL, Lee WS, Lee FY, Hwang SJ. Peer-assisted learning model enhances clinical clerk's procedural skills. JCMA 2018;81(8):747-753 (SCI).
24. Yang YY*, Wang SJ,* Yang LY, Lirng JF, Huang CC, Liang JF, Lee FY, Hwang SJ, Huang CC, Kirby Rh.. Parallel trainings intensify Chinese pre-clerk's history-taking and physical-examination skills and clerkship' preparedness: a prospective comparative study in primary health-care center and campus. BMJ Open. 2017 Sep 25;7(9):e016294 (SCI).
25. Yang LY, Yang YY*, Huang CC, Liang JF, Lee FY, Cheng HM, Huang CC, Kao SY. Simulation based inter-professional education to improve attitudes towards    collaborative practice: a prospective comparative pilot study in a Chinese medical center. BMJ Open. 2017;0:e015105 (SCI).
26. Lee FY, Yang YY*, Hsu HC, Chuang CL, Lee WS, Chang CC, Huang CC, Chen JW, Cheng HM, Jap TS. Clinical instructors, perception of a faculty development program promoting postgraduate year-1 (PGY1) residents‘ ACGME six core competencies: a 2-year study. BMJ Open 2011; 1(2) (SCI).
27. Yang LY, Huang CC, Hsu HC, Yang YY*, Chang CC, Chuang CL, Lee WS, Liang JF, Cheng HM, Huang CC, Lee FY, Ho ST, Kirby R. Voluntary attendance of small-group brainstorming tutoring courses intensify new clerk's "excellence in clinical care": a pilot study. BMC Med Educ. 2017;17(1):2 (SCI).
28. Yang YY*, Yang LY, Hsu HC, Huang CC, Huang CC, Kirby R, Cheng HM, Chang CC, Chuang CL, Liang JF, Lin CC, Lee WS, Ho ST, Lee FY. A model of four hierarchical levels to train Chinese residents' teaching skills for "practice-based learning and improvement" competency. Postgrad Med. 2015;127(7):744-51(SCI).
29. Huang CC, Huang CC, Yang YY, Lin SJ, Chen JW. The influence of gender on the communication skills assessment of medical students. Eur J Intern Med. 2015;26(9):670-4 (SCI).

生科代表著作

1. YY Yang, SL Hsieh, PC Lee, YC Yeh, KC Lee, YC Hsieh, YW Wang, TY Lee, YH Huang, CC Chan, HC Lin. Long-term cannabinoid type 2 receptor agonist therapy decreases Bacterial Translocation In Rats with cirrhosis and ascites. J Hepatol 2014;61(5):1004-13.
2. Ying-Ying Yang, Tung-Hu Tsai, Yi-Tsau Huang, Tzung-Yan Lee, Che-Chang Chan, Kuei-Chuan Lee, Han-Chieh Lin. Hepatic Endothelin-1 and Endocannabinoids-Dependent Effects of Hyperleptinaemia in Nonalcoholic Steatohepatitis-Cirrhotic Rats. Hepatology 2012; 55: 1540-50.
3. Han-Chieh Lin, Ying-Ying Yang, Tung-Hu Tsai, Chih-Ming Huang, Yi-Tsau Huang, Fa-Yauh Lee, Tze-Tze Liu, Shou-Dong Lee. The relationship between endotoxemia and hepatic endocannabinoids in cirrhotic rats with portal hypertension. J Hepatol 2011;45:1145-53.
4. Yang YY, Liu HQ, Nam SW, Kunos G, Lee SS. Mechanisms of TNFα-induced cardiac dysfunction in cholestatic bile duct-ligated mice: interaction between TNFα and endocannabinoids. J Hepatol 2010;53(2):298-306.
5. YY Yang, HC Lin, WP Lee, CJ Chu, MW Lin, FY Lee, MC Hou, JS Jap, SD Lee Association of the G-protein and alpha-2 adrenergic receptor gene and plasma norepinephrine level with clonidine improvement of effects of diuretics in cirrhotic patients with refractory ascites: a randomized clinical trial. Gut 2010;59:1545-53.
6. Ying-Ying Yang, Kuei-Chuan Lee, Yi-Tsau Huang, Ying-Wen Wang, Ming-Chih Hou, Fa-Yauh Lee, Han-Chieh Lin, Shou-Dong Lee. Effects of N-acetylcysteine administration in hepatic microcirculation of rats with biliary cirrhosis. J Hepatol 2008;49(1):25-33.
7. Ying-Ying Yang, Han-Chieh Lin, Yi-Tsau Huang, Ming-Chih Hou, Fa-Yauh Lee, Full-Young Chang, Shou-Dong Lee. Inhibition of glucagon improves splanchnic hyporesponse to terlipressin in cirrhotic rats with blood retention in the gastric lumen. J Hepatol 2005;42:652-8.
8. Ying-Ying Yang, Han-Chieh Lin, Yi-Tsau Huang, Tzung-Yen Lee, Ming-Chih Hou, Fa-Yauh Lee, Ren-Shyan Liu, Full-Young Chang, Shou-Dong Lee. Effect of one-week losartan administration on bile duct-ligated cirrhotic rats with portal hypertension. J Hepatol 2002;36:600-6.
9. Chia-Chang Huang,Hsiao-Yun Yeh, Roger Li1, Tsai-Ling Liao, Hsiao-Chin Shen, Ying-Ying Yang* and Han-Chieh Lin. Inhibition of visceral adipose tissue-derived pathogenic signals by activation of adenosine A2AR improves hepatic and cardiac dysfunction of NASH mice. Am J Physiol Gastrointest Liver Physiol. 2024 Jan 22. doi: 10.1152/ajpgi.00104.2023.
10. CC Huang, HC Shen, R Lin, YY Yang*, et al. Preservation of vascular endothelial glycocalyx and barrier by activation of adenosine A2A receptor (A2AR) improved renal dysfunction in cirrhotic rats. J Pharmacological Sciences, 2023;152(1):50-60.
11. YH Lin, NR Kuo, HC Shen, YC Chang, Roger Lin, TL Liao, HY Yeh*, YY Yang*, MC Hou, HC Lin. Prediction models combining zonulin, LPS, and LBP predict acute kidney injury and hepatorenal syndrome–acute kidney injury in cirrhotic patients. Scientific Reports 2023;13(1):13048.
12. Nai-Rong Kuo, Ming-Chih Hou*, Wei-Chi Chu, Ying-Ying Yang*, Chia-Chang Huang, Tzu-Hao Li, Tzung-Yan Lee, Chih-Wei Liu, Tsai-Ling Liao, Shie-Liang Hsieh, Han-Chieh Lin*. Low lymphocyte-to-monocyte ratio, calcitriol level and CD206 level predict the development of ACLF in cirrhotic patients with acute decompensation. JCMA 2023;86(3):265-273.
13. Liu SY, Huang CC, Yang YY*, Huang SF, Lee TY, Li TH, Hou MC, Lin HC. Obeticholic acid treatment ameliorates the cardiac dysfunction in NASH mice. Plos One 2022; 17(12): e0276717. 
14. Liu Szu-Yu, Huang Chia-Chang, Shiang-Fen Huang, Tsai-Ling Liao, Nai-Rong Kuo, Ying-Ying Yang*, Tzu-Hao Li, Chih-Wei Liu, Ming-Chih Hou, Han-Chieh Lin. Pioglitazone ameliorates acute endotoxemia-induced acute on chronic renal dysfunction in cirrhotic ascitic rats. Cells 2021, 10(11), 3044.
15. Hsu CF, Huang CC, Liu TT, Yang UC, Liu CW, Huang SF, Yang YY*, Huang YH, Hou MC, Lin HC. Deletion of intestinal SIRT1 exacerbated muscle wasting in cirrhotic mice by decreasing the intestinal concentration of short-chain fatty acids and inflammation. J Pharmacological Sciences, 2021:147(4), 376-385.
16. Yu-Lien Tsai, Chih-Wei Liu, Chien-Fu Hsu, Chia-Chang Huang, Ming-Wei Lin, Shiang-Fen Huang, Tzu-Hao Li, Kuei-Chuan Lee, Yun-Cheng Hsieh, Ying-Ying Yang*, Tzung-Yan Lee, Hsuan-Miao Liu, Yi-Hsiang Huang, Ming-Chih Hou, Han-Chieh Lin*. Obeticholic acid ameliorates hepatorenal syndrome in ascitic cirrhotic rats by down-regulating the renal 8-iso-PGF2α-activated COX-TXA2 pathway. Clin Sci (Lond). 2020;134(15):2055-2073.
17. Hung-Cheng Tsai, Chien-Fu Hsu, Chia-Chang Huang, Shiang-Fen Huang, Tzu-Hao Li, Ying-Ying Yang*, Ming-Wei Lin, Tzung-Yan Lee, Chih-Wei Liu, Yi-Hsiang Huang , Ming-Chih Hou, Han-Chieh Lin*. Propranolol Suppresses the T-Helper Cell Depletion-Related Immune Dysfunction in Cirrhotic Mice. Cells 2020, 9(3), 604.
18. Tzu-Hao Li, Ying-Ying Yang*, Chia-Chang Huang, Chih-Wei Liu, Hung-Cheng Tsai , Ming-Wei Lin, Chang-Youh Tsai , Shiang-Fen Huang , Ying-Wen Wang , Tzung-Yan Lee, Yi-Hsiang Huang, Ming-Chih Hou, Han-Chieh Lin*. Elafibranor interrupts adipose dysfunction-mediated gut and liver injury in mice with alcoholic steatohepatitis. Clin Sci (Lond). 2019;133(3):531-544.
19. Chih-Wei Liu, Chia-Chang Huang, Hung-Cheng Tsai, Yen-Bo Su , Shiang-Fen Huang, Kuei-Chuan Lee , Yun-Cheng Hsieh, Tzu-Hao Li, Chang-Youh Tsai, Lee-Won Chong, Shuo-Ming Ou, Ying-Ying Yang*, Wen-Chien Fan 2, Ming-Chih Hou, Han-Chieh Lin, Shou-Dong Lee. Serum Adrenomedullin and Urinary Thromboxane B2 help Early Categorizing Acute kidney injury in De-compensated Cirrhotic Patients: a prospective cohort study. Hep Res 2018;48(3):E9-E21.
20. Chih-Wei Liu, Hung-Cheng Tsai, Chia-Chang Huang, Chang-Youh Tsai, Yen-Bo Su, Ming-Wei Lin , Kuei-Chuan Lee, Yun-Cheng Hsieh, Tzu-Hao Li, Shiang-Fen Huang, Ying-Ying Yang *, Ming-Chih Hou, Han-Chieh Lin , Fa-Yauh Lee , Shou-Dong Lee. Effects and mechanisms of caffeine to improve immunologic and metabolic abnormalities in diet-Induced obese rats. Am J Physiol Endocrinol Metab 2018;314(5):E433-47.
21. YB Su, TH Li , CC Huang, HC Tsai, SF Huang, YC Hsieh , YY Yang*, YH Huang, MC Hou, HC Lin. Chronic calcitriol supplementation improves the inflammatory profiles of circulating monocytes and the associated intestinal/adipose tissue alteration in a diet-induced steatohepatitis rat model. PLoS One. 2018;13(4):e0194867.
22. HC Tsai, Tzu-Hao Li, Chia-Chang Huang, Shiang-Fen Huang, Ren-Shyan Liu, Ying-Ying Yang*, Yun-Cheng Hsieh, Kuei-Chuan Lee , Yi-Hsiang Huang, Ming-Chih Hou, Han-Chieh Lin. Beneficial effects of the PPARα/γ agonist aleglitazar on progressive hepatic and splanchnic abnormalities in cirrhotic rats with portal hypertension. Am J Pathology 2018;188(7):1608-1624.
23. WC Fan, CC Huang, YY Yang*, A Lin, KC Lee, YC Hsieh, CP Fung, HC Hsu, MC Hou, HC Lin*. Serum pentraxin-3 and TNF-like weak inducer of apoptosis (TWEAK) predict severity of infections in acute de-compensated cirrhotic patients. J Micro Immunol Infect 2017;50(6):905-914.
24. Lee PC, Yang LY, Wang YW, Huang SF, Lee KC, Hsieh YC, Yang YY*, Hsieh SL, Hou MC, Lin HC,* Lee FY, Lee SD. Mechanisms of the prevention and inhibition of the progression and development of NASH by genetic and pharmacological DcR3 supplementation. Hep Res 2017 Nov;47(12):1260-1271.
25. Li TH, Liu CW, Lee PC, Huang CC, Lee KC, Hsieh YC, Yang YY*, Hsieh SL, Lin HC, Tsai CY. Decoy receptor 3 analogous supplement protects steatotic rat liver from ischemia-reperfusion injury. J Chin Med Assoc. 2017;80(7):391-400.
26. Li TH, Lee PC, Lee KC, Hsieh YC, Tsai CY, Yang YY*, Huang SF, Tsai TH, Hsieh SL, Hou MC, Lin HC*, Lee SD. Down-regulation of common NFκB-iNOS pathway by chronic Thalidomide treatment improves Hepatopulmonary Syndrome and Muscle Wasting in rats with Biliary Cirrhosis. Sci Rep 2016;6:39405.
27. Lee PC, Yang YY*, Huang CS, Hsieh SL, Lee KC, Hsieh YC, Lee TY, Lin HC. Concomitant inhibition of oxidative stress and angiogenesis by chronic hydrogen-rich saline and N-acetylcysteine treatments improves systemic, splanchnic and hepatic hemodynamics of cirrhotic rats. Hep Res 2015:45:578-588.
28. Yang YY, Lee PC, Huang YT, Lee WP, Kuo YJ, Lee KC, Hsieh YC, Lee TY, Lin HC. Involvement of the HIF-1a and Wnt/b-catenin pathways on the protective effects of losartan on fatty liver graft with ischemia/reperfusion injury. Clin Sci (Lond) 2014; 126: 163-174.
29. Yang YY, Liu RS, Lee PC, Yeh YC, Huang YT, Lee WP, Lee KC, Hsieh YC, Lee FY, Tan TW, Lin HC. Anti-VEGFR agents ameliorate hepatic venous dysregulation/microcirculatory dysfunction, splanchnic venous pooling and ascites of NASH-cirrhotic rat. Liver Int 2014;34: 521-34.
30. Lin HC, Huang YT, Yang YY, Lee PC, Hwang LH, Lee WP, Kuo YJ, Lee KC, Hsieh YC, Liu RS. Beneficial effects of dual VEGFR/FGFR inhibitor brivanib alaninate in cirrhotic portal hypertensive rats. J Gastroenterol Hepatol 2014;29:1073-82 (co-first author).
31. Lee PC, Yang YY*, Lee WP, Lee KC, Hsieh YC, Lee TY, Lin H. Vitamin D3 treatment has comparative portal hypotensive effects as propranolol by decreasing intrahepatic resistance in cirrhotic rats. J Gastroenterol Hepatol 2015;30(3):628-37(corresponding author).
32. Yang YY, Hou MC, Lin MW, Chen PH, Liao WC, Chu CJ, Lin HC*. Combined platelet count with sCD163 and genetic variants optimizes esophageal varices prediction in cirrhotic patients. J Gastroenterol Hepatol 2013; 28 (1): 112-21.
33. Fan WC, Liu WC, Ou SM, Huang CC, Li TH, Lee KC, Huang SF, Yang YY*, Hsieh YC, Hsieh SL, Hou MC, Lin HC* TLR4/CD14 variants-Related Serologic and Immunologic dys-regulations Predict Severe Sepsis in Febrile De-Compensated Cirrhotic Patients. PLoS One. 2016 18;11(11):e0166458.
34. Li TH, Huang CC, Yang YY*, Lee KC, Hsieh SL, Hsieh YC, Alan L, Lin HC*, Lee SD, Tsai CY. Thalidomide Improves the Intestinal Mucosal Injury and Suppresses Mesenteric Angiogenesis and Vasodilatation by Down-Regulating Inflammasomes-Related Cascades in Cirrhotic Rats. PLoS One. 2016 28;11(1):e0147212.
35. PC Lee, YY Yang*, MC Hou, CS Huang, KC Lee, YW Wang, YC Hsieh, YH Huang, CJ Chu, HC Lin. Benzodiazepine-Associated Hepatic Encephalopathy Significantly Increased Healthcare Utilization and Medical Cost of Chinese Cirrhotic Patients: 7-years Experiences. Diges Dis Sci 2014; 59(7):1603-16..
36. Yang YY, Lee TY, Huang YT, Chan CC, Yeh YC, Lee FY, Lee SD, Lin HC. Asymmetric dimethylarginine (ADMA) determines the improvement of hepatic endothelial dysfunction by vitamin E in cirrhotic rats. Liver Int 2012; 32:48-57.
37. Yang YY, Huang YT, Tsai TH, Hou MC, Lee FY, Lee SD, Lin HC*. Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A2 release in a rodent model of NASH cirrhosis. Clin Sci (Lond) 2012; 123: 669-680.
38. Yang YY, Huang YT, Lee TY, Chan CC, Yeh YC, Lee KC, Lin HC*. Rho-Kinase-Dependent Pathway Mediated the Hepatoprotective Effects of Sorafenib for Ischemia/Reperfusion Liver Injury of NASH Rats. Liver Transplant 2012;18:1371-83.
39. Yang YY, Lin HC, Lin MW, Chu CJ, Lee FY, Hou MC, Lee SD, Lee WP, Liu TT, Jap TS. Identification of diuretic non-responders with poor long-term clinical outcomes: a 1-year follow-up of 176 non-azotaemic cirrhotic patients with moderate ascites. Clin Sci 2011; 121, 509-21.
40. Lee KC, Yang YY*, Huang YT, Lee FY, Hou MC, Lin HC, Lee SD. Administration of a low dose of sildenafil for 1 week decreases intrahepatic resistance in rats with biliary cirrhosis: the role of NO bioavailability. Clin Sci 2010;119(1):45-55 (*co-first author).
41. Yang YY, Lee KC, Huang YT, Lee FY, Chau GY, Loong CC, Lin HC, Lee SD. Inhibition of hepatic tumor necrosis factor-alpha attenuates the anandamide-induced vasoconstrictive response in cirrhotic rat livers. Liver Int 2009;29(5):678-85.
42. Yang YY, Huang YT, Lee KC, Lee FY, Lee TY, Hou MC, Lin HC, Lee SD. Chronic administration of ursodeoxycholic acid decreases portal pressure in rats with biliary cirrhosis. Clin Sci (Lond) 2009;116(1):71-9.
43. Lee KC, Yang YY*, Wang YW, Hou MC, Lee FY, Lin HC, Lee SD. Acute administration of sildenafil enhances hepatic cyclic guanosine monophosphate production and reduces hepatic sinusoidal resistance in cirrhotic patients. Hep Res 2008;38:1186-93 (*co-first author).
44. Yang YY, Lin HC, Huang YT, Lee TY, Hou MC, Wang YW, Lee FY, Lee SD. Effect of chronic CB1 cannabinoid receptor antagonism on livers of rats with biliary cirrhosis. Clin Sci (Lond) 2007;112(10):533-42.
45. Wang YW, Hou TI, Yang YY, Hou MC, Lee PC, Lin HC, Lee FY, Chi CW, Lee SD. Correlation and comparison of the model for end-stage liver disease, portal pressure, and serum sodium for outcome prediction in patients with liver cirrhosis, J Clin Gastroenterol 2007;41:706-12.
46. Yang YY, Lin HC, Huang YT, Lee TY, Hou MC, Wang YW, Lee FY, Lee SD. Role of Ca2+-dependent potassium channels in in vitro anandamide-mediated mesenteric vasorelaxation in rats with biliary cirrhosis. Liver Int 2007; 7(8):1045-55.
47. Yang YY, Lin HC, Huang YT, Lee TY, Hou MC, Wang YW, Lee FY, Lee SD. Roles of anandamide in the hepatic microcirculation in cirrhotic rats. Am J Physiol Gastrointest Liver Physiol 2006;290(2):G328-34.
48. Yang YY, Lin HC, Lee WC, Huang YT, Hou MC, Lee FY, Chang FY, Lee SD. Plasma erythropoietin level in patients with cirrhosis and its relationship to the severity of cirrhosis and renal function. J Gastroenterol Hepatol 2003;18:1156-61.
49. Yang YY, Lin HC, Lee WC, Hou MC, Lee FY, Chang FY, Lee SD. One-week losartan administration increases sodium excretion in cirrhotic patients with and without ascites. J Gastroenterol 2002; 7:194-9.
50. Yang YY, Lin HC, Lee WC, Hou MC, Lee FY, Chang FY, Lee SD. Portopulmonary hypertension: distinctive hemodynamic and clinical manifestation. J Gastroenterol 2001;36:181-6.
51. Yang YY, Lin HC, Huang YT, Lee TY, Lee WC, Hou MC, Lee FY, Chang FY, Lee SD. Adaptive vasodilatory response after octreotide treatment. Am J Physiol Gastrointest Liver Physiol 2001;281:G117-23.

出版品：

• 醫學書籍

Yang YY, Lin HC. Diagnostic laboratory tests. In: Lee SS & Moreau R, eds. Cirrhosis. A practical guide to management. John Wiley & Sons Ltd. 2015;12-20.

• 醫學教育書籍

1.      楊盈盈，許心怡，楊令瑀，黃加璋等。高擬真醫學模擬教育訓練教材影片及教學案例全集，台北榮民總醫院，2016年1月出版。(總策劃、編輯及總校閱)

2.      楊盈盈，楊令瑀，侯重光，程雅琳，楊惠文等。2016超"急"救命術;高級心臟救命術(重點整理與教案演練)，台北榮民總醫院。2017年2月出版。(總策劃、編輯及總校閱)

3.      楊盈盈，楊令瑀，高壽延，張德明，羅文良，龔彥穎等。跨領域團隊全人照護暨臨床推廣標竿分享集錦，百禾文化資訊有限公司。2016年12月出版。(總策劃、編輯及總校閱)

• 多媒體教材

高擬真醫學模擬教育訓練教材影片及教學案例全集&超"急"救命術;高級心臟救命術，台北榮民總醫院2016年1月及2017年2月出版。跨領域團隊全人照護暨臨床推廣標竿分享集錦。百禾文化資訊有限公司2016年12月出版。雲端科技跨領域高擬真模擬醫學多媒體教材，跨領域團隊全人照護暨臨床推廣標竿分享集錦，創新結合Diamond DAA與TRM回饋模式，的跨領域團隊合作醫學模擬教案集錦(中、英文版)，XR系列教材 AI虛擬體驗XR氣切決策。百禾文化資訊有限公司2018年1&6月&2019年8月出版。並獲6項教學相關專利。