姓名：陳涵栩

科部：內科部 內分泌暨新陳代謝科

聯絡方式：

電話   8#1319

Email   chenhs@vghtpe.gov.tw 

學歷：

國立陽明大學 臨床醫學研究所 博士

中國醫藥大學 醫學士   

經歷：

臺北榮民總醫院 內科部 內分泌暨新陳代謝科 主任

國立陽明大學 醫學院內科教授

研究方向：

本研究室近年對於糖尿病，IGF-1以及肢端肥大症的研究已有一些成果。研究人員主要的專長有動態內分泌功能的檢查，糖尿病的衛教，包括教導血糖機的使用及胰島素的注射，流行病學及生物統計。本實驗室還能夠自行測定糖化血色素，果糖胺，血糖，胰島素（IRI，Total insulin，free insulin，insulin Ab），IGF-1，IGFBP3，眼底檢查等。

五年內研究著作：

1. Chang LH, Wu TE, Chen HS*. Factors Responsible for Combined Glucose Intolerance Developing into Isolated Post-challenge Hyperglycemia in Subjects with Impaired Fasting Glucose. International Journal of Diabetology & Vascular Disease Research. 2015; 3(7) 115-121.
2. Hsien-Hao Huang, Harn-Shen Chen, Yu-Fong Syu, Chih-Yen Chen. Short-term proton pump inhibitor therapy with or without Helicobacter pylori eradication does not lead to weight gain in patients with gastric ulcer older than 40 years. Surg Obes Relat Disease. 2015; 11: 1187–1189.
3. Harn-Shen Chen, Hong-Da Lin, Chen-Hsen Lee. Thyroid Emergencies: Thyroid Storm & Myxedema Coma in the Textbook of Endocrine Surgery edited by Drs. Clark, Duh, Gosnell, and Shen. 2015, 3rd edition. 
4. Ya-Wun Guo, Tzu-En Wu, Harn-Shen Chen*. Prognostic Factors of Mortality among Patients with Severe Hyperglycemia in the Emergency Room. American Journal of Managed Care. 2015; 21: 9-22
5. Tzu-En Wu, Yu-Hsin Chen, Harn-Shen Chen*. Effects of glucose and blood pressure control on diabetic kidney disease in old patients with type 2 diabetes. Diabetology & Metabolic Syndrome. 2014; 6: 81-88.   
6. Harn-Shen Chen*, Tzu-En Wu, Chin-Sung Kuo. Long-term glycemic control after 6-month of basal insulin therapy. American Journal of Managed Care. 2014; 20: e369-79.
7. Tzu-En Wu, Harn-Shen Chen*. Research update for articles published in EJCI:  Interaction between glycemic control and serum insulin-like growth factor 1 on the risk of retinopathy in type 2 diabetes. European Journal of Clinical Investigation. 2014; 44: 1010-1023.
8. Yu-Hsin Chen, Harn-Shen Chen*, Der-Cherng Tarng*. More impact of microalbuminuria on retinopathy than moderately reduced GFR among type 2 diabetic patients. Diabetes Care. 2012; 35: 803-808.
9. Harn-Shen Chen*. Role of IGF-1 and glycaemic control in diabetic retinopathy: The authors reply. European Journal of Clinical Investigation. 2012; 42: 805-806.
10. Harn-Shen Chen*, Tzu-En Wu, Li-Chuan Hsiao, Shu-Hsia Lin. Interaction between glycemic control and serum insulin-like growth factor 1 on the risk of retinopathy in type 2 diabetes. European Journal of Clinical Investigation. 2012; 42: 447-454.
11. Tzu-En J. Wu, Chen-Chang Yang*, Harn-Shen Chen*. Does atropine use increase intraocular pressure in myopic children? Optometry and Vision Science. 2012; 89(2): E161-7.
12. Harn-Shen Chen*, Tzu-En Wu, Tjin-Shing Jap, Li-Chuan Hsiao, Hong-Da Lin, Shen-Hung Lee, Shu-Hsia Lin. Effects of Long-Acting Release Octreotide on Glucose Homeostasis in Acromegaly Patients after Trans-Sphenoidal Surgery. Hormone and Metabolic Research. 2011; 43: 433-439.

研究室成員：

郭錦松、林怡君、張立心、黃君睿、李奕彥、蘇郁文、李佳欣。