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Laboratory of Head and Neck Cancer Research

TEL: +886-2-28712121 #7382

E-mail: khfung@vghtpe.gov.tw

Principal Investigator: Kai-Feng Hung, D.D.S., MS, Ph.D.

 

Education
2009–2015    Ph.D., Department of Oral Biology, University of Washington
2000–2004    M.S., Oral and Maxillofacial Surgery, National Yang-Ming University
1994–2000    D.D.S., School of Dentistry, Taipei Medical University

Profession and Experience
2016–present    Physician Scientist, Department of Medical Research and Education, Taipei Veterans General Hospital, Taiwan
2016–present    Attending Physician, Department of Oral and Maxillofacial Surgery, Taipei Veterans General Hospital, Taiwan
2015–present    Assistant Professor, Department of Dentistry, National Yang-Ming University, Taiwan
2015–2016    Attending Physician, Division of Oral and Maxillofacial Surgery, National Yang-Ming University Hospital, Taiwan
2006–2009    Attending Physician, Division of Oral and Maxillofacial Surgery, Tzu Chi General Hospital, Taiwan

Clinical Training
2015    Visiting Fellow, Orthognathic Surgery, Swedish Hospital, Northwest Hospital
2015     Visiting Fellow, Head and Neck Surgery Department, University of Washington Medical Center, Harborview Medical Center
2000–2006    Resident, Division of Oral and Maxillofacial Surgery, Department of Dentistry, Taipei Veterans General Hospital, Taiwan

Kai-Feng Hung

<Specialty>

Molecular Cancer Biology and Research, Surgical Oncology of Head and Neck Cancer, Orthognathic Surgery, Dentistry

<Honor and Awards>

2014     Albert M. Kligman Travel Fellowship Award, Society for Investigative Dermatology Annual Meeting, Albuquerque, NM

2013     Graduate School Fund for Excellence and Innovation (GSFEI) Graduate Student Travel Award, School of Dentistry, University of Washington

2011     1st Place Poster Award, 6th Annual South Lake Union Group (SLUG) Research Symposium

2009     Graduate School Fund for Excellence and Innovation Top Scholar Award, School of Dentistry, University of Washington

2004     Oral Presentation Award, 4th Taiwan Congress on Oral and Maxillofacial Surgery Annual Meeting, Tainan, Taiwan

2003     Oral Presentation Award, 3th Taiwan Congress on Oral and Maxillofacial Surgery Annual Meeting, Changhua, Taiwan

2002     Best Graduate of Year Award, National Yang-Ming University, Taipei, Taiwan

<Board Certificate and License>

Diplomate, National Board of Oral and Maxillofacial Surgery, Taiwan

Dental License, Taiwan

<Professional Organization>

Member, Taiwan Head and Neck Tumor Society

Member, Academic Affairs Committee and International Affairs Committee, Association of Oral and Maxillofacial Surgeons, Taiwan

Member, Taiwan Dental Association

<Publication>

  1. Hung KF, Chen BH, Wang TY, Yang YP, Chien Y, Lo JF, Yang L, Peng BY, Kao SY, Wu CH. Identification of plasma hsa_circ_0000190 and 0001649 as biomarkers for predicting the recurrence and treatment response of patients with oral squamous cell carcinoma. J Chin Med Assoc. 85(4):431-437 (2022) 
  2. Sun YC, Wu LL, Chang YA, Li TY, Lin Y, Hu FR, Tsai WB, Hung KF. Zwitterionic poly(carboxybetaine methacrylate) (polyCBMA) decreases desiccating damage to corneal epithelial cells. Colloid Interface Sci Commun. 50:100648 (2022). 
  3. Wang ML, Lin Y, Hou JF, Yang YP, Chien Y, Sun YC, Liang KH, Yang DM, Chang TJ, Wu CH, Kao SY, Hung KF. The Omicron variant wave: Where are we now and what are the prospects? J Chin Med Assoc. doi: 10.1097/JCMA.0000000000000863 (2022). 
  4. Liang KH, Hung KF, Wang ML, Chang TJ, Cheng YF, Chiang SH, Chen MF, Liao YT, Chiou SH, Yang DM. SARS-CoV-2 vaccines in children and adolescents: Can immunization prevent hospitalization? J Chin Med Assoc. 85(9):891-895 (2022).
  5. Sun YC, Hung KF, Li TY, Chang YA, Yeh PT, Hu FR. Transmembrane mucin 1 blocks fluorescein ingress to corneal epithelium. Invest Ophthalmol Vis Sci. 63(2):31 (2022).
  6. Hung KF, Hung CH, Hong C, Chen SC, Sun YC, Wen JW, Kuo CH, Ko CH, Cheng CM. Quantitative spectrochip-coupled lateral flow immunoassay demonstrates clinical potential for overcoming Coronavirus Disease 2019 pandemic screening challenges. Micromachines. 12(3):321-33 (2021). 
  7. Sun YC, Inamoto Y, Wang RK, Lee SJ, Hung KF, Shen TT. The disposable bandage soft contact lenses therapy and anterior segment optical coherence tomography for management of ocular graft-versus-host disease. BMC Ophthalmol. 21(1):271 (2021). 
  8. Liang KH, Lin YY, Chiang SH, Tsai ET, Lo WL, Wang CL, Wang TY, Sun YC, Kao SY, Wu CH, Hung KF. Recent progress of biomarkers in oral cancers. J Chin Med Assoc. 84(11):987-992 (2021). 
  9. Chang YA, Wu YY, Lin CT, Kawasumi M, Wu CH, Kao SY, Yang YP, Hsu CC, Hung KF, Sun YC. Animal models of dry eye: Their strengths and limitations for studying human dry eye disease. J Chin Med Assoc. 84(5):459-464 (2021). 
  10. Hung KF, Sidorova JM, Nghiem P, Kawasumi M. The 6-4 Photoproduct is the trigger of UV-induced replication blockage and ATR activation. Proc Natl Acad Sci U S A. 117(23):12806-12816 (2020).
  11. CY Chen, Kawasumi M, Lan TY, Poon CL, Lin YS, Wu PJ, Chen YC, Chen BH, Wu CH, Lo JF, Weng RR, Sun YC, Hung KF. Adaptation to endoplasmic reticulum stress enhances resistance of oral cancer cells to cisplatin by up-regulating polymerase η and increasing DNA repair efficiency. Int J Mol Sci. 22(1):355 (2020). 
  12. Hung KF, Sun YC, Chen BH, Lo JF, Cheng CM, Chen CY, Wu CH, Kao SY. New COVID-19 saliva-based test: How good is it compared with the current nasopharyngeal or throat swab test? J Chin Med Assoc. 83(10):891-894 (2020). 
  13. Liao WT, Hsu MY, Shen CF, Hung KF, Cheng CM. Home sample self-collection for COVID-19 patients. Advanced Biosystems, (11):e2000150 (2020). 
  14. Lin WY, Chen YW, Lin CF, Yang YP, Wang ML, Hung KF, Huang PI, Lee YY, Chiou SH. Emerging trends in gene-modified-based chimeric antigen receptor-engineered T-cellular therapy for malignant tumors: The lesson from leukemia to pediatric brain tumors. J Chin Med Assoc. 83(8):719-724 (2020).
  15. Chou CJ, Lin CF, Chen YW, Huang PI, Yang YP, Wang ML, Hung KF, Lee YY. The update of chimeric antigen receptor-T cells therapy in glioblastoma. J Chin Med Assoc. 83(5):442-445 (2020).
  16. Lee JW, Ratnakumar K, Hung KF, Rokunohe D, Kawasumi M. Deciphering UV-induced DNA damage responses to prevent and treat skin cancer. Photochem Photobiol. 96(3):478-499 (2020).
  17. Hung KF, Liao PC, Chen CK, Chiu YT, Cheng DH, Kawasumi M, Kao SY, Lo JF. ASB6 promotes the stemness properties and sustains metastatic potential of oral squamous cell carcinoma cells by attenuating ER stress. Int J Biol Sci. 15(5):1080-1090 (2019). 
  18. Hung KF, Sun YC, Liou HM, Hu FR. Human antigen R protein modulates vascular endothelial growth factor expression in human corneal epithelial cells under hypoxia. J Formos Med Assoc. S0929-6646(19):30217-7 (2019). 
  19. Akbor M, Hung KF, Yang YP, Chou SJ, Tsai PH, Chien CS, Lin LT. Immunotherapy orchestrates radiotherapy in composing abscopal effects: A strategic review in metastatic head and neck cancer. J Chin Med Assoc. 83(2):113-116 (2019).
  20. Hung KF, Yang T, Kao SY. Cancer stem cell theory: Are we moving past the mist? J Chin Med Assoc. 82(11):814-818 (2019). 
  21. Chen YS, Chang CW, Tsay YG, Huang LY, Wu YC, Cheng LH, Yang CC, Wu CH, Teo WH, Hung KF, Huang CY, Lee TC, Lo JF. HSP40 co-chaperone protein Tid1 suppresses metastasis of head and neck cancer by inhibiting Galectin-7-TCF3-MMP9 axis signaling. Theranostics. 8(14):3841-3855 (2018).
  22. Chang CW, Chen YS, Tsay YG, Han CL, Chen YJ, Yang CC, Hung KF, Lin CH, Huang TY, Kao SY, Lee TC, Lo JF (2018, Feb). ROS-independent ER stress-mediated NRF2 activation promotes warburg effect to maintain stemness-associated properties of cancer-initiating cells. Cell Death Dis. 9(2):194 (2018).
  23. Hung KF, Liu CJ, Chiu PC, Lin JS, Chang KW, Shi WY, Kao SY, Tu HF. MicroRNA-31 upregulation predicts increased risk of progression of Oral Potentially Malignant Disorder. Oral Oncol. 53:42-7 (2016). 
  24. Cheng LH, Hung KF, Lee TC, Huang CY, Chiu WT, Lo JF, Huang TF. Mitochondrial co-chaperone protein Tid1 is required for energy homeostasis during skeletal myogenesis. Stem Cell Res Ther. 7(1):185-194 (2016).
  25. Cheng LH, Hung KF, Huang TF, Hsieh HP, Wang SY, Huang CY, Lo JF. Attenuation of cancer-initiating cells stemness properties by abrogating S100A4 calcium binding ability in head and neck cancers. Oncotarget. 7(48):78946-78957 (2016).

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