E-mail: ycteng6@vghtpe.gov.tw

EDUCATION

Ph.D.｜Sep 2010-Jan 2017  Program in Molecular Medicine, School of Life Sciences, National Yang-Ming University, Taiwan

M.S.｜Jul 2005-Aug 2007   Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taiwan

B.S.｜Sep 2001-Jun 2005    Department of Life Science, Tunghai University, Taiwan

PROFESSIONAL CAREER

Assistant researcher fellow｜Mar 2022 – present  Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan

Postdoctoral fellow｜Aug 2021 – Feb 2022  Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan

Postdoctoral fellow｜Mar 2017-Dec 2017 & Jun 2020-Jul 2021  Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei, Taiwan

Postdoctoral fellow｜Jan 2018-Dec 2019  Research Center for Gene Therapy, Department of Biophysics, Federal University of São Paulo, São Paulo, Brazil

Grants

New layer of developmental regulation in retinal axonogenesis: the m6A RNA modification (NSTC 112-2311-B-075-001 / PI)

TECHNICAL SKILLS

Mouse Genetics, molecular pathology, molecular biology, systemic biology, NGS

AWARDS AND HONORS

• (2018) 17^th Japanese Association for Laboratory Animal Science [International Award, invited oral presentation]
• (2018) 14^th Veterans General Hospitals University System of Taiwan Excellent Research Article Award [Second prize, Teng et al. J Pathol (2018)]
• (2017) 15^th Conference of the Chinese-Taipei Society of Laboratory Animal Science [First prize, oral presentation]
• (2017) Outstanding Research Article Award of the Prof. Juei-Low Sung’s Research Foundation
• (2017) Doctor Thesis Competition of National Yang-Ming University [First prize, oral presentation]
• (2017) The 25th Symposium on Recent Advances in Cellular and Molecular Biology [Dr. Chien-Tien Hsu's Award, oral presentation]
• (2016) 14^th Conference of the Chinese-Taipei Society of Laboratory Animal Science [Excellent award, oral presentation]
• (2016) Cold Spring Harbor Asia Conferences: Liver Metabolism, Diseases and Cancer [Fellowship award, poster]
• (2013) Mini-symposium on Mitochondria and Aging [Bronze prize, poster]
• (2012) 8^th Veterans General Hospitals University System of Taiwan Poster Competition [First prize, poster]
• (2012) Macky International Symposium: Mitochondrial Dysfunction and Aging-related Diseases [poster award]
• (2011) 11^th Conference of the Chinese-Taipei Society of Laboratory Animal Science [Excellent award, oral presentation]
• (2011) 7^th Veterans General Hospitals University System of Taiwan Poster Competition [Second prize, poster]
• (2007) Dean of School of Life Science Prize, National Yang-Ming University
• (2007) National Yang-Ming University Annual Thesis Competition [Excellent Award, poster]
• (2005) Luce Scholarship, Tunghai University
• (2003) Prof. Chen Fung-shien Scholarship, Tunghai University
• (2002) Prof. Chen Fung-shien Scholarship, Tunghai University

PUBLICATIONS

1. HC Hong*, CH Lin*, YC Teng*, PY Wang, BW Song, CH Kao, TF Tsai. A dominant negative effect of Kcnd3 F227del mutation causes SCA22 via impairing ER and Golgi functions in a mouse model. *, co-first author. [under revision in J Pathol; IF=7.3].
2. YC Teng, YL Chung, YF Chen, YH Hsu, N Itoh, TF Tsai. Skeletal muscle is a master regulator in adiposity and systemic metabolism during accelerated aging. [under revision in EMBO rep; IF=7.7]
3. CC Hsu, HK Chuang, YJ Hsiao, YC Teng, PH Chiang, YJ Wang, TY Lin, PH Tsai, CC Weng, TC Lin, DK Hwang, AR Hsieh. Polygenic Risk Score Improves Cataract Prediction in East Asian Population. (2022) Biomedicines, 10(8):1920 [IF=4.7]
4. CH Yeh, ZQ Shen, YJ Chou, TW Wang, CH Kao, YC Teng, TK Yeh, CK Lu, TF Tsai. Hesperetin promotes longevity and delays aging via activation of Cisd2 in naturally aged mice. (2022) J Biomed Sci, 29: 53 [IF=11.0]
5. RH Chou, MY Yang, YP Yang, CA Yeh, WY Lai, TW Lin, YC Teng, SC Hsieh, ML Kung, HH Hsieh, HS Hung. Evaluating the biocompatibility and biological performance of FePt-decorated nano-epoxy nanoparticles in mesenchymal stem cells. (2021) J Chin Med Assoc, 84(12):1109 [IF=3.0]
6. PC Teng, Y Liang, AA Yarmishyn, YJ Hsiao, TY Lin, TW Lin, YC Teng, YP Yang, ML Wang, CS Chien, YH Luo, YM Chen, PK Hsu, SH Chiou, Y Chien. RNA modifications and epigenetics in modulation of lung cancer and pulmonary diseases. (2021) Int J Mol Sci, 22:10592 [IF=5.6]
7. CY Lee, CH Huang, E Rastegari, V Rengganaten, PC Liu, PH Tsai, YF Chin, JR Wu, SH Chiou, YC Teng, CW Lee, Y Liang, AY Chen, SC Hsu, YJ Hung, JR Sun, CS Chien, Y Chien. Tumor necrosis factor-alpha exacerbates viral entry in SARS-CoV2-infected iPSC-derived cardiomyocytes. (2021) Int J Mol Sci, 22:9869 [IF=5.6]
8. YL Huang, ZQ Shen, CH Huang, YC Teng, CH Lin, TF Tsai. Cisd2 protects liver from oxidative stress and ameliorates western diet-induced nonalcoholic fatty liver disease. (2021) Antioxidants, 10:559 [IF=7.0]
9. YC Teng, AL Porfírio-Sousa, GM Ribeiro, MC Arend, LDS Meirelles, ES Chen, DS Rosa, SW Han. Analyses of the pericyte transcriptome in ischemic skeletal muscles. (2021) Stem Cell Res Ther, 12:183 [IF=7.5]
10. ZQ Shen, YL Huang, YC Teng, TW Wang, CH Kao, CH Yeh, TF Tsai. CISD2 maintains cellular homeostasis. (2021) Biochim Biophys Acta-Mol Cell Res, 1868:118954 [IF=5.1]
11. YC Teng, JY Wang, YH Chi, TF Tsai. Exercise and the Cisd2 Prolongevity Gene: Two Promising Strategies to Delay the Aging of Skeletal Muscle. (2020) Int J Mol Sci, 21:9059 [IF=5.6]
12. CP Yang, WS Yang, YH Wong, KH Wang, YC Teng, MH Chang, KH Liao, FS Nian, CC Chao, JW Tsai, WL Hwang, MW Lin, TY Tzeng, PN Wang, Mel Campbell, LK Chen, TF Tsai, PC Chang, HJ Kung. Muscle atrophy‐related myotube‐derived exosomal microRNA in neuronal dysfunction: Targeting both coding and long noncoding RNAs. (2020) Aging Cell, 00:e13107 [IF=7.8]
13. WP Wang, JY Wang, WH Lin, CH Kao, MC Hung, YC Teng, TF Tsai, YH Chi. Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis. (2019) Aging Cell, 19:e13090 [IF=7.8]
14. CH Yeh, ZQ Shen, SY Hsiung, CY Wu, PC Wu, YC Teng, YJ Chou, SW Fang, CF Chen, YT Yan, LS Kao, CH Kao, TF Tsai. Cisd2 is essential to delaying cardiac aging and to maintaining heart electromechanical functions. (2019) PLoS Biol, 17: e3000508 [IF=9.8]
15. YL Huang, ZQ Shen, CY Wu, YC Teng, CC Liao, CH Kao, LK Chen, CH Lin, TF Tsai. Comparative proteomic profiling reveals a role for Cisd2 in skeletal muscle aging. (2018) Aging Cell, 17:e12705 [IF=7.8]
16. YC Teng, JC Neo, JC Wu, YF Chen, CH Kao, TF Tsai. Expression of a hepatitis B virus pre-S2 deletion mutant in the liver results in hepatomegaly and hepatocellular carcinoma in mice. (2017) J Pathol, 241:463 [IF=7.3]
17. YC Teng, ZQ Shen, CH Kao, TF Tsai. Hepatocellular carcinoma mouse models: Hepatitis B virus-associated hepatocarcinogenesis and haploinsufficient tumor suppressor genes. (2016) World J Gastroenterol, 22:300 [IF=4.3]
18. SH Wang, SH Yeh, CW Shiau, KF Chen, WH Lin, TF Tsai, YC Teng, DS Chen, PJ Chen. Sorafenib Action in Hepatitis B Virus X-Activated Oncogenic Androgen Pathway in Liver through SHP-1. (2015) J Natl Cancer Inst, 107: djv190 [IF=13.757]