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TEL: +886-2-28712121 Ext.2655
E-mail: ctwang@vghtpe.gov.tw |
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| Principal Investigator: Chin-Tien Wang | |
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1984 Bachelor of Medicine, School of Medicine, Kaohsiung Med. College 1993 Ph.D., Dept. of Microbiol. and Immunology., Oregon Health Sciences Univ., USA 1993 ~ 2001 Associate Prof., Institute of Clinical Medicine, Natl. Yang-Ming Univ 1995 ~ present Adjunct Investigator, Dept. Med. Res. & Edu., Taipei Veterans General Hospital. 2002 ~ 2020 Jointed-appointed Prof., Institute of Public Health, Natl. Yang-Ming Univ. 2001 ~ present Prof., Institute of Clinical Medicine, Natl. Yang-Ming Univ. 08/2018-present Professor and Chair, Institute of Clinical Medicine, National Yang Ming Chiao Tung University. Director, Translational Medicine Degree Program, National Yang Ming Chiao Tung University. |
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| <Research Interests> | |
| I. Virus-like particle assembly of human immunodeficiency virus type 1 and human coronavirus II. Antiviral activity of human APOBEC3G. |
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| <Selected Recent Publications> | |
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1. Fu-Hsien Yu and Chin-Tien Wang*. 2018. HIV-1 protease with leucine zipper fused at N-terminus exhibits enhanced linker amino acid-dependent activity. Retrovirology15:32 https://doi.org/10.1186/s12977-018-0413-6 2. Shiu-Mei Wang, Kuo-Jung Huang, Chin-Tien Wang*. 2019. Severe acute respiratory syndrome coronavirus spike protein counteracts BST2-mediated restriction of virus-like particle release. J. Med. Virol. 91(10):1743-1750. 3. Fu-Hsien Yu, Kuo-Jung Huang and Chin-Tien Wang* 2020. HIV-1 Mutant Assembly, Processing and Infectivity Expresses Pol Independent of Gag. Viruses 12(1):54. https://doi.org/10.3390/v12010054 4. Fu-Hsien Yu, Kuo-Jung Huang and Chin-Tien Wang*. 2021. Conditional activation of an HIV-1 protease attenuated mutant by a leucine zipper dimerization motif. Virus Research Apr 2;295:198258. doi: 10.1016/j.virusres. https://doi.org/10.1016/j.virusres.2020.198258 5. Fu-Hsien Yu, Kuo-Jung Huang and Chin-Tien Wang*. 2022. Amino acid substitutions at the HIV-1 transframe region significantly impair virus infectivity. PLOS ONE 17 (1): e0262477 https://doi.org/10.1371/journal.pone.0262477 6. Yi-Ru Lin, Shih-Ming Chu, Fu-Hsien Yu, Kuo-Jung Huang and Chin-Tien Wang*. Effects of reduced gag cleavage efficiency on HIV-1 Gag-Pol package. BMC Microbiol. 22, 94 (2022). https://doi.org/10.1186/s12866-022-02503-3 |
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