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分子遺傳研究室

TEL: +886-2-28712121 Ext.3265
E-mail: mychung@vghtpe.gov.tw
主持人:鍾明怡
現職 鍾明怡副教授
2005 -今 國立陽明交通大學生命科學系暨基因體科學研究所副教授
2005 -今 臺北榮民總醫院醫學研究部副研究員
學歷
1983-1987 國立台灣大學醫事技術學系學士
1987-1989 美國明尼蘇達大學Clinical Laboratory Science碩士
1989-1993 美國明尼蘇達大學病理生物學(Pathobiology)博士
 
經歷
1994 美國明尼蘇達大學博士後研究員
1995-1997 臺北榮民總醫院病理檢驗部約聘技術師
1997-2005 臺北榮民總醫院教學研究部副研究員
2002-2005 國立陽明大學遺傳學研究所兼任副教授

 

《研究興趣與方向》

利用分子遺傳學、基因體學、與幹細胞學的方法找尋並了解基因在人類疾病中所扮演的角色。目前研究方向包含:

1. 黃斑部病變之表現形與基因型間的關係,以及基因治療的開發。

2. 家族性滲漏性玻璃體視網膜病變基因在NDP/wnt/β-catenin singaling pathway與 angiogenesis中的角色。

3. 10q26基因多型性在老年性黃斑部病變的角色。

《近期研究著作》

1. Kuo CY, Chung MY*, Chen SJ* (2023) Pseudocoloboma-like maculopathy with biallelic RDH12 missense mutations. J Med Genet. doi:10.1136/jmg-2022-108918 (IF2021=6.318, Rank=12.6%(22/175); GENETICS & HEREDITY)

2. Jiang YJ, Fann CS, Fuh JL, Chung MY, Huang HY, Chu KC, Wang YF, Hsu CL, Kao LS, Chen SP, Wang SJ (2022) Genome-wide analysis identified novel susceptible genes of restless legs syndrome in migraineurs. J Headache Pain 23 (1):39. doi:10.1186/s10194-022-01409-9 (IF2021=7.277, Rank=9.6%(20/208); CLINICAL NEUROLOGY)

3. Chung MY*, Chen SJ, Jiang YJ (2021) Phenotype Variability in the Patients of Familial Exudative Vitreoretinopathy: the RCBTB1 case. Curr Eye Res 46 (12):1931. doi:10.1080/02713683.2021.1924383 (IF2021=2.42; Rank=57.5%; OPHTHALMOLOGY)

4. Chen PC, Huang HY, Chung MY, Pan CC (2021) Ossifying low grade endometrial stromal sarcoma with PHF1-BRD8 fusion. Cancer Genet 256-257:81-85. doi:10.1016/j.cancergen.2021.04.006 (IF2021=2.523; Rank=44.1%; GENETICS & HEREDITY)

5. Wu CC, Hsieh MY, Lee CK, Chuang SY, Chung MY*, Lin CC* (2019) Dimethylarginine Dimethylaminohydrolase 1 Polymorphisms and Venous Intimal Hyperplasia in Hemodialysis Patients. American journal of nephrology 50 (6):454-464. doi:10.1159/000503949 (IF2021=3.754; Rank=28.9% UROLOGY & NEPHROLOGY)

6. Liao KW, Chang CH, Tsai MS, Chien LC, Chung MY, Mao IF, Tsai YA, Chen ML (2018) Associations between urinary total arsenic levels, fetal development, and neonatal birth outcomes: A cohort study in Taiwan. The Science of the total environment 612:1373-1379. doi:10.1016/j.scitotenv.2017.08.312 (IF2021=7.963; Rank: 10.95% PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH)

7. Chen S-P1, Fuh J-L1, Chung M-Y1, Lin Y-C, Liao Y-C, Wang Y-F, Hsu C-L, Yang U-C, Lin M-W, Chiou J-J, Wang P-J, Chen P-K, Fan P-C, Wu J-Y, Chen Y-T, Kao L-S, Fann CS-J, Wang S-J (2018) Genome-wide association study identifies novel susceptibility loci for migraine in Han Chinese resided in Taiwan. Cephalalgia : an international journal of headache 38 (3):466-475. doi:doi:10.1177/0333102417695105 (IF2021=6.075 ; Rank=21.57% CLINICAL NEUROLOGY)

8. Chang CH, Yu CJ, Du JC, Chiou HC, Chen HC, Yang W, Chung MY, Chen YS, Hwang B, Mao IF, Chen ML (2018) The interactions among organophosphate pesticide exposure, oxidative stress, and genetic polymorphisms of dopamine receptor D4 increase the risk of attention deficit/hyperactivity disorder in children. Environmental research 160:339-346. doi:10.1016/j.envres.2017.10.011 (IF2021=6.498, Rank=6.35% ENVIRONMENTAL SCIENCES)

9. Yu CJ, Du JC, Chiou HC, Yang SH, Liao KW, Yang W, Chung MY, Chien LC, Hwang B, Chen ML (2016) Attention Deficit/Hyperactivity Disorder and Urinary Nonylphenol Levels: A Case-Control Study in Taiwanese Children. PloS one 11 (2):e0149558. doi:10.1371/journal.pone.0149558

10. Yu CJ, Du JC, Chiou HC, Feng CC, Chung MY, Yang W, Chen YS, Chien LC, Hwang B, Chen ML (2016) Sugar-Sweetened Beverage Consumption Is Adversely Associated with Childhood Attention Deficit/Hyperactivity Disorder. International journal of environmental research and public health 13 (7):E678. doi:10.3390/ijerph13070678

11. Yu CJ, Du JC, Chiou HC, Chung MY, Yang W, Chen YS, Fuh MR, Chien LC, Hwang B, Chen ML (2016) Increased risk of attention-deficit/hyperactivity disorder associated with exposure to organophosphate pesticide in Taiwanese children. Andrology 4 (4):695-705. doi:10.1111/andr.12183

12. Wu JH, Liu JH, Ko YC, Wang CT, Chung YC, Chu KC, Liu TT, Chao HM, Jiang YJ*, Chen SJ*, Chung MY* (2016) Haploinsufficiency of RCBTB1 is associated with Coats disease and familial exudative vitreoretinopathy. Human molecular genetics 25 (8):1637-1647. doi:10.1093/hmg/ddw041

13. Lee KH, Tsai WJ, Chen YW, Yang WC, Lee CY, Ou SM, Chen YT, Chien CC, Lee PC, Chung MY*, Lin CC* (2016) Genotype polymorphisms of genes regulating nitric oxide synthesis determine long-term arteriovenous fistula patency in male hemodialysis patients. Renal failure 38 (2):228-237. doi:10.3109/0886022X.2015.1120096

14. Fuh JL1, Chung MY1, Yao SC, Chen PK, Liao YC, Hsu CL, Wang PJ, Wang YF, Chen SP, Fann CS, Kao LS, Wang SJ (2016) Susceptible genes of restless legs syndrome in migraine. Cephalalgia : an international journal of headache 36 (11):1028-1037. doi:10.1177/0333102415620907

15. Chen YW, Wu YT, Lin JS, Yang WC, Hsu YH, Lee KH, Ou SM, Chen YT, Shih CJ, Lee PC, Chan CH, Chung MY*, Lin CC* (2016) Association of Genetic Polymorphisms of Renin-Angiotensin-Aldosterone System-Related Genes with Arterio-Venous Fistula Malfunction in Hemodialysis Patients. International journal of molecular sciences 17 (6). doi:10.3390/ijms17060833

 

Google Scholar: ‪MING-YI CHUNG - ‪Google Scholar

ORCiD: 0000-0003-2198-6860

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