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頭頸部腫瘤研究室

TEL: +886-2-28752434 Ext. 27382
E-mail: [email protected]

主持人:洪凱風
1994 ~ 2000 台北醫學大學牙醫系 洪凱風醫師
2000 ~ 2004 國立陽明大學臨床牙醫研究所口腔顎面外科碩士
2000 ~ 2006 臺北榮民總醫院住院醫師
2006 ~ 2009 慈濟綜合醫院台北分院主治醫師
2009 ~ 2014 美國華盛頓大學口腔醫學博士
2014 ~ 2015 美國西北醫院顱顎顏面外科臨床研究員
  美國華盛頓大學醫學院頭頸外科臨床交換學者
2015 ~ 2016 國立陽明大學附設醫院口腔醫學部主治醫師
2017 ~ 迄今 臺北榮民總醫院醫學研究部主治醫師
《研究興趣》
(1) 癌症免疫治療 (Cancer immunotherapy) 及標靶治療 (target therapy) 
(2) DNA損傷及修復 (DNA damage responses and repair) 
(3) 小分子藥物 (small molecule drug) 篩選
《代表著作 》
  1. Hung KF, Chen BH, Wang TY, Yang YP, Chien Y, Lo JF, Yang L, Peng BY, Kao SY, Wu CH. Identification of plasma hsa_circ_0000190 and 0001649 as biomarkers for predicting the recurrence and treatment response of patients with oral squamous cell carcinoma. J Chin Med Assoc. 85(4):431-437 (2022) 本人為第一作者.
  2. Sun YC, Wu LL, Chang YA, Li TY, Lin Y, Hu FR, Tsai WB, Hung KF. Zwitterionic poly(carboxybetaine methacrylate) (polyCBMA) decreases desiccating damage to corneal epithelial cells. Colloid Interface Sci Commun. 50:100648 (2022). 本人為通訊作者.
  3. Wang ML, Lin Y, Hou JF, Yang YP, Chien Y, Sun YC, Liang KH, Yang DM, Chang TJ, Wu CH, Kao SY, Hung KF. The Omicron variant wave: Where are we now and what are the prospects? J Chin Med Assoc. doi: 10.1097/JCMA.0000000000000863 (2022). 本人為通訊作者.
  4. Liang KH, Hung KF, Wang ML, Chang TJ, Cheng YF, Chiang SH, Chen MF, Liao YT, Chiou SH, Yang DM. SARS-CoV-2 vaccines in children and adolescents: Can immunization prevent hospitalization? J Chin Med Assoc. 85(9):891-895 (2022).
  5. Sun YC, Hung KF, Li TY, Chang YA, Yeh PT, Hu FR. Transmembrane mucin 1 blocks fluorescein ingress to corneal epithelium. Invest Ophthalmol Vis Sci. 63(2):31 (2022).
  6. Hung KF, Hung CH, Hong C, Chen SC, Sun YC, Wen JW, Kuo CH, Ko CH, Cheng CM. Quantitative spectrochip-coupled lateral flow immunoassay demonstrates clinical potential for overcoming Coronavirus Disease 2019 pandemic screening challenges. Micromachines. 12(3):321-33 (2021). 本人為第一作者.
  7. Sun YC, Inamoto Y, Wang RK, Lee SJ, Hung KF, Shen TT. The disposable bandage soft contact lenses therapy and anterior segment optical coherence tomography for management of ocular graft-versus-host disease. BMC Ophthalmol. 21(1):271 (2021). 本人為共同通訊作者.
  8. Liang KH, Lin YY, Chiang SH, Tsai ET, Lo WL, Wang CL, Wang TY, Sun YC, Kao SY, Wu CH, Hung KF. Recent progress of biomarkers in oral cancers. J Chin Med Assoc. 84(11):987-992 (2021). 本人為通訊作者.
  9. Chang YA, Wu YY, Lin CT, Kawasumi M, Wu CH, Kao SY, Yang YP, Hsu CC, Hung KF, Sun YC. Animal models of dry eye: Their strengths and limitations for studying human dry eye disease. J Chin Med Assoc. 84(5):459-464 (2021). 本人為共同通訊作者.
  10. Hung KF, Sidorova JM, Nghiem P, Kawasumi M. The 6-4 Photoproduct is the trigger of UV-induced replication blockage and ATR activation. Proc Natl Acad Sci U S A. 117(23):12806-12816 (2020). 本人為第一作者.
  11. CY Chen, Kawasumi M, Lan TY, Poon CL, Lin YS, Wu PJ, Chen YC, Chen BH, Wu CH, Lo JF, Weng RR, Sun YC, Hung KF. Adaptation to endoplasmic reticulum stress enhances resistance of oral cancer cells to cisplatin by up-regulating polymerase η and increasing DNA repair efficiency. Int J Mol Sci. 22(1):355 (2020). 本人為通訊作者.
  12. Hung KF, Sun YC, Chen BH, Lo JF, Cheng CM, Chen CY, Wu CH, Kao SY. New COVID-19 saliva-based test: How good is it compared with the current nasopharyngeal or throat swab test? J Chin Med Assoc. 83(10):891-894 (2020). 本人為第一作者.
  13. Liao WT, Hsu MY, Shen CF, Hung KF, Cheng CM. Home sample self-collection for COVID-19 patients. Advanced Biosystems, (11):e2000150 (2020). 本人為共同通訊作者.
  14. Lin WY, Chen YW, Lin CF, Yang YP, Wang ML, Hung KF, Huang PI, Lee YY, Chiou SH. Emerging trends in gene-modified-based chimeric antigen receptor-engineered T-cellular therapy for malignant tumors: The lesson from leukemia to pediatric brain tumors. J Chin Med Assoc. 83(8):719-724 (2020).
  15. Chou CJ, Lin CF, Chen YW, Huang PI, Yang YP, Wang ML, Hung KF, Lee YY. The update of chimeric antigen receptor-T cells therapy in glioblastoma. J Chin Med Assoc. 83(5):442-445 (2020).
  16. Lee JW, Ratnakumar K, Hung KF, Rokunohe D, Kawasumi M. Deciphering UV-induced DNA damage responses to prevent and treat skin cancer. Photochem Photobiol. 96(3):478-499 (2020).
  17. Hung KF, Liao PC, Chen CK, Chiu YT, Cheng DH, Kawasumi M, Kao SY, Lo JF. ASB6 promotes the stemness properties and sustains metastatic potential of oral squamous cell carcinoma cells by attenuating ER stress. Int J Biol Sci. 15(5):1080-1090 (2019). 本人為第一作者.
  18. Hung KF, Sun YC, Liou HM, Hu FR. Human antigen R protein modulates vascular endothelial growth factor expression in human corneal epithelial cells under hypoxia. J Formos Med Assoc. S0929-6646(19):30217-7 (2019). 本人為第一作者.
  19. Akbor M, Hung KF, Yang YP, Chou SJ, Tsai PH, Chien CS, Lin LT. Immunotherapy orchestrates radiotherapy in composing abscopal effects: A strategic review in metastatic head and neck cancer. J Chin Med Assoc. 83(2):113-116 (2019).
  20. Hung KF, Yang T, Kao SY. Cancer stem cell theory: Are we moving past the mist? J Chin Med Assoc. 82(11):814-818 (2019). 本人為第一作者.
  21. Chen YS, Chang CW, Tsay YG, Huang LY, Wu YC, Cheng LH, Yang CC, Wu CH, Teo WH, Hung KF, Huang CY, Lee TC, Lo JF. HSP40 co-chaperone protein Tid1 suppresses metastasis of head and neck cancer by inhibiting Galectin-7-TCF3-MMP9 axis signaling. Theranostics. 8(14):3841-3855 (2018).
  22. Chang CW, Chen YS, Tsay YG, Han CL, Chen YJ, Yang CC, Hung KF, Lin CH, Huang TY, Kao SY, Lee TC, Lo JF (2018, Feb). ROS-independent ER stress-mediated NRF2 activation promotes warburg effect to maintain stemness-associated properties of cancer-initiating cells. Cell Death Dis. 9(2):194 (2018).
  23. Hung KF, Liu CJ, Chiu PC, Lin JS, Chang KW, Shi WY, Kao SY, Tu HF. MicroRNA-31 upregulation predicts increased risk of progression of Oral Potentially Malignant Disorder. Oral Oncol. 53:42-7 (2016). 本人為第一作者.
  24. Cheng LH, Hung KF, Lee TC, Huang CY, Chiu WT, Lo JF, Huang TF. Mitochondrial co-chaperone protein Tid1 is required for energy homeostasis during skeletal myogenesis. Stem Cell Res Ther. 7(1):185-194 (2016).
  25. Cheng LH, Hung KF, Huang TF, Hsieh HP, Wang SY, Huang CY, Lo JF. Attenuation of cancer-initiating cells stemness properties by abrogating S100A4 calcium binding ability in head and neck cancers. Oncotarget. 7(48):78946-78957 (2016).

 

 

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