Some images has been designed using resources from Unsplash & Pixabay & Pexels & Freepik and some icons from Flaticon
跳到主要內容
Search
:::

李宜中 (Yi-Chung Lee)

李宜中(Yi-Chung Lee)圖 Return Appointment First Appointment

[Profile]

  • Education
    • 2004.9-2008.5 Ph.D. program, Institute of Clinical medicine, National Yang-Ming University,
    • 2003.10-2004.3 Research Volunteer, Pulmonary Division, Harvard Medical School affiliated Brigham and Women’s Hospital,
    • 2002.7-2004.3 Fellowship in Neurology, Taipei Veterans General Hospital, Taiwan,
    • 1999.1-2002.6 Residency in Neurology, Taipei Veterans General Hospital, Taiwan,
    • 1998.7-1999.1 Residency in Neurology, Chung-Hsiao Municipal Hospital, Taipei, Taiwan,
    • 1995-1996 Internship at Taipei Veterans General Hospital,
    • 1989-1996 M.D. National Yang-Ming University School of Medicine,
  • Career and Experience
    Current Positions：
    • - Now, 2017.2-now Professor, Department of Neurology, National Yang-Ming University School of Medicine,
    • - Now, 2008.11-now Attending Physician, Department of Neurology, Taipei Veterans General Hospital,
    • - Now, 2008.8-2012.8 Asistant Professor, Department of Neurology, National Yang-Ming University School of Medicine,
    Experiences：
    • - , 2012.8-2017.2 Associate Professor, Department of Neurology, National Yang-Ming University School of Medicine,
    • - , 2004.3-2004.6 Attending Physician, Department of Neurologogy, Taipei Veteran General Hospital, Taiwan,
    • - , 2004.6-2008.11 Attending Physician, Section of Neurology, Department of Internal Medicine, Taichung Veterans General Hospital,
  • Medical Expertise
    1. Neurogenetics
    2. Peripheral neuropathy
    3. Neurodegenerative diseases
  • License
    2001 Taiwan Board of Neurology

[Publications]

經歷:
台北市立忠孝醫院 神經內科 住院醫師
台北榮民總醫院 神經內科 住院醫師
哈佛醫學院附屬布列根婦女醫院分子生物學研究進修
台中榮民總醫院 神經內科 主治醫師 (2004.6~2008.11)
台北榮民總醫院 神經內科 主治醫師 2008.11-至今
臺灣神經學會神經基因學組主委
科技部神經醫學學門召集人 (2018.1.1~2020.12.31)

得獎紀錄:
1. 102年臺北榮總醫師最佳論文獎第二名
2. 103年臺北榮總醫師最佳論文獎第二名 (兩項)
3. 104年臺北榮總醫師最佳論文獎佳作
4. 107年臺北榮總醫師最佳論文獎第一名
5. 108年臺北榮總醫師最佳論文獎佳作
6. 109年臺灣腦中風學會最佳論文獎特優

臨床專長:
走路不穩、四肢麻木、家族性中風、家族性神經退化疾病、家族性周邊神經病變、運動神經元疾病 (漸凍人與甘迺迪氏症)、基因檢測及周邊神經病變。

 

疾病專長:

神經退化及遺傳疾病，如遺傳性腦中風CADASIL、運動神經元疾病 (漸凍人與甘迺迪氏症)、遺傳性周邊神經病變 (CMT)、家族性類澱粉神經病變 (FAP)、遺傳性腦白質病變、小腦萎縮症、巴金森氏症、亨丁頓舞蹈症、神經元核內包含體疾病 (NIID)、基因診斷及發炎性周邊神經病變、遺傳性痙攣性截癱症HSP。


研究方向：
神經退化及遺傳疾病 (如遺傳性腦中風CADASIL、遺傳性運動感覺神經病變CMT、漸凍人ALS、甘迺迪氏症、家族性類澱粉神經病變、小腦萎縮症SCA、遺傳性痙攣性截癱症HSP）

 

媒體影音報導:

1. 北榮找到「腦中風突變基因」 台灣人約1%有此基因 (公視晚間新聞2020年12月14日)

2. 北榮找到台灣人特有"腦中風"突變基因...這種人要注意! (TVBS新聞台十點不一樣2020年12月22日)

3. FAP 家族性澱粉樣多發性神經病變 見曙光 20220302雲端保健室第19集

4. 百岳高手卻突走路不穩！手腳發麻無力四處求醫卻找不出病因...後發現竟是罹患罕見疾病FAP (三立新聞台【台灣亮起來】2021年9月26日

5. 家有罕病兒，父母當如何？基因檢測等病症出現再驗？正向心態和支持何處尋？ (顏肩肱肌肉萎縮症) 黃瑽寧愛+好醫生

6. 運動感覺神經病變 肇因基因突變 (公視晚間新聞 2013年4月8日)

7. 確診「漸凍症」逐漸喪失生活自理能力 (TVBS新聞 2017年9月6日)

 

 

論文發表: 

  1. Hsu SL, Liao YC, Wu CH, Change FC, Chen YL, Lai KL, Chung CP, Chen SP*, Lee YC*. Impaired Cerebral Interstitial Fluid Dynamics in CADASIL. Brain Communications 2024;6(1): fcad349.
  2. Lin X*, Jiang JY, Hong DJ, Lin KJ, Chen YJ, Qiu YS, Wang Z, Liao YC, Yang K, Shi Y, Wang MW, Hsu SL, Hong S, Zeng YH, Chen XC, Wang N, Lee YC*, Chen WJ*. Biallelic COQ4 variants in hereditary spastic paraplegia: clinical and molecular characterization. Movement disorders 2023Nov 28. doi: 10.1002/mds.29664.
  3. Chou YT, Hsu SL, Tsai YS, Lu YJ, Yu KW, Wu HM, Liao YC, Lee YC*. Biallelic DDHD2 mutations in patients with adult-onset complex hereditary spastic paraplegia. Ann Clin Transl Neurol 2023 Sep;10(9):1603-1612.
  4. Liao YC, Wei CY, Chang FP, Chou YT, Hsu SL, Chung CP, Mizuguchi T, Matsumoto N, Yet SF, Lee YC*. NOTCH2NLC GGC repeat expansion in patients with vascular leukoencephalopathy. Stroke 2023;54(5):1236-45.
  5. Fang SY, Chou YT, Hsu KC, Hsu SL, Yu KW, Tsai YS, Liao YC, Lee YC*. Clinical and genetic characterization of NIPA1 mutations in a Taiwanese cohort with hereditary spastic paraplegia. Ann Clin Transl Neurol 2023;10(3):353-62.
  6. Hsu SL, Liao YC, Lin KP, Lin PY, Yu KW, Tsai YS, Guo YC, Lee YC*. Investigating KIF1A mutations in a Taiwanese cohort with hereditary spastic paraplegia. Parkinsonism Relat Disord 2022 Sep 16;103:144-149.
  7. Liu YH, Chou YT, Chang FP, Lee WJ, Guo YC, Chou CT, Huang HC, Mizuguchi T, Chou CC, Yu HY, Yu KW, Wu HM, Tsai PC, Matsumoto N, Lee YC*, Liao YC*. Neuronal intranuclear inclusion disease in patients with adult-onset non-vascular leukoencephalopathy. Brain 2022 Sep 14;145(9):3010-21.
  8. Wang YF, Liao YC, Tzeng YS, Chen SP, Lirng JF, Fuh JL, Chen WT, Lai KL, Lee YC*, Wang SJ*. Mutation screening and association analysis of NOTCH3 p.R544C in patients with migraine with or without aura. Cephalalgia 2022 Aug;42(9):888-898.
  9. Liao YC, Chang FP, Huang HW, Chen TB, Chou YT, Hsu SL, Jih K, Liu YH, Hsiao CT, Fukukda H, Mizuguchi T, Lin KK, Lin CK, Matsumoto N, Kennerson M, Lee YC*. GGC Repeat Expansion of NOTCH2NLC in Taiwanese Patients With Inherited Neuropathies. Neurology 2022;98(2):e199-206.
  10. Hsu SL, Chen YH, Chou CT, Chou YT, Tsai YS, Hsiao CT, Liao YC*, Lee YC*. Investigating ABCD1 mutations in a Taiwanese cohort with hereditary spastic paraplegia phenotype. Parkinsonism Relat Disord 2021;92:7-12.
  11. Tsai PC, Fuh JL, Yang CC, Chang A, Lien LM, Wang PN, Lai KL, Tsai YS, Lee YC*, Liao YC. Clinical and genetic characterization of CSF1R-related leukoencephalopathy in a Taiwanese cohort with adult-onset leukoencephalopathy. Ann Clin Transl Neurol; 2021;8(11):2121-31.
  12. Tsai PC, Jih KY, Shen TY, Liu YH, Lin KP, Liao YC, Lee YC*. Genetic and functional analysis of GLT8D1 in Taiwanese patients with amyotrophic lateral sclerosis. Neurol Genet 2021;7(6)e627
  13. Chiang HL, Fuh JL, Tsai YS, Soong BW, Liao YC, Lee YC*. Expanding the phenotype of AFG3L2 mutations: Late-onset autosomal recessive spinocerebellar ataxia. J Neurol Sci 2021;428:117600.
  14. Liao YC, Hu YC, Chung CP, Wang YF, Guo YC, Tsai YS, LeeYC*. Intracerebral hemorrhage in CADASIL: prevalence, clinical and neuroimaging features and risk factors. Stroke 2021;52(3):985-93.
  15. Jih KY, Tsai PC, Tsai YS, Liao YC, Lee YC*. Rapid progressive ALS in a patient with a DNAJC7 loss-of-function mutation. Neurol Genet 2020;6 (5):e503.
  16. Tsai YS, Lin KP, Jih KY, Tsai PC, Liao YC, Lee YC*. Hand-onset Weakness Is a Common Feature of ALS Patients With a NEK1 Loss-Of-Function Variant. Ann Clin Transl Neurol. 2020 Jun;7(6):965-971.
  17. Chou CT, Soong BW, Lin KP, Tsai YS, Jih KY, Liao YC, Lee YC*. Clinical characteristics of Taiwanese patients with Hereditary spastic paraplegia type 5.Ann Clin Transl Neurol. 2020;7(4):486-496.
  18. Lee YC, Chung CP, Chang MH, Wang SJ, Liao YC*. NOTCH3 cysteine-altering variant is an important risk factor for stroke in Taiwanese population. Neurology 2020;94(1):e87-e96.
  19. Hsu YH, Lin KP, Guo YC, Tsai YS, Liao YC, Lee YC*. Mutation spectrum of Charcot-Marie-Tooth disease among the Han Chinese in Taiwan. Ann Clin Transl Neurol 2019;6(6): 1090-1101.
  20. Chao HC, Liao YC, Liu YT, Guo YC, Chang FP, Lee YC*, KP Lin*. Clinical and genetic profiles of hereditary transthyretin amyloidosis in Taiwan. Ann Clin Transl Neurol 2019;6(5):913-922.
回到最上