Precision Preventive Medicine and Genetic Testing

Specialist:
Chia-Ming Chang

Overview

Genomic medicine is an evolving field that uses advancements in genomics and high-throughput sequencing technologies to enhance the diagnosis and treatment of genetic diseases. Next-generation sequencing (NGS) has revolutionized the field, providing a powerful tool for uncovering the genetic basis of diseases and enabling more precise and personalized healthcare.

Features

Here are some of the crucial applications of genomic medicine we offer in our department：

• Diagnostic Testing: Genomic testing is used to diagnose genetic conditions and determine carriership status for inherited diseases. This information helps guide clinical decision-making, such as predicting disease risk or determining appropriate medical management.
• Personalized Medicine: By analyzing a patient's genomic data, healthcare providers can gain insights into their individual biology and tailor medical treatment to their specific needs, leading to improved patient outcomes with fewer side effects.
• Cancer Genomics: Cancer is a disease caused by genetic mutations, and genomic medicine plays a significant role in cancer diagnosis and treatment. By analyzing a person's cancer genomic data, doctors can identify specific genetic mutations that drive cancer, allowing them to select targeted therapies that are most likely to be effective.
• Precision Medicine: Precision medicine is an approach to healthcare that considers individual differences in people's genes, environments, and lifestyles. By using genomic information, healthcare providers can provide more personalized and effective treatments, improving patient outcomes.
• Pharmacogenomics: Pharmacogenomics is the study of how a person's genomic information influences their response to drugs. By using pharmacogenomic testing, healthcare providers can determine a person's genetic variations that affect drug metabolism, determining the best dose and medications for that individual.

Applications and personalization

Given the significance of genomic information related to one's health, comprehensive genetic tests are provided to grasp the key factors for a person's health accurately. Based on whole genome sequencing (WGS) or whole exome sequencing (WES), single-gene analysis and polygenic analysis are carried out, checking for both rare genetic diseases and the genetic cause or predisposition of common complex diseases, such as cancer, dementia, and diabetes. Therefore, in the Department of Obstetrics and Gynecology, our specialists provide the scope of the application includes:

1. Precision preventive medicine for healthy individuals looking to find the exact direction for preventing potential diseases.
2. Precision and personalized medicine
3. Finding the cause of diseases of unknown origin
4. Genetic testing for hereditary diseases in families
5. Pre-marital genetic testing
6. Any disease or issues related to genes.