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研究成果回報

發表論文目錄
  年份 期刊
1 2014 Hsei-Wei Wang, Shung-Haur Yang, Guan-Da Huang, Jen-Kou Lin, Wei-Shone Chen, Jeng-Kai Jiang, Yuan-Tzu Lan, Chun-Chi Lin, Wei-Lun Hwang, Cheng-Hwai Tzeng, Anna Fen-Yau Li, Chueh-Chuan Yen, Hao-Wei Teng. Temsirolimus enhances the efficacy of cetuximab in colon cancer through a CIP2A?dependent mechanism. J Cancer Res Clin Oncol. 2014, 140:561-571.
2 2015 Pei-Ching Lin, Jen-Kou Lin, Chien-Hsing Lin, Hung-Hsin Lin, Shung-Haur Yang, Jeng-Kai Jiang, Wei-Shone Chen, Chih-Chi Chou, Shih-Feng Tsai and Shih-Ching Chang. Clinical Relevance of Plasma DNA Methylation in Colorectal Cancer Patients Identified by Using a Genome-Wide High-Resolution Array. Ann Surg Oncol. 2015;22:S1419-27.
3 2015 Kuo-Hung Huang, Yuan-Tzu Lan, Wen-Liang Fang, Jen-Hao Chen, Su-Shun Lo, Anna Fen-Yau Li, Shih-Hwa Chiou, Chew-Wun Wu, and Yi-Ming Shyr. The correlation between miRNA and lymph node metastasis in gastric cancer. Biomed Res Int. 2015 ;2015:543163.
4 2015 Chia-Chu Chang, Hung-Hsin Lin, Jen-Kou Lin, Chun-Chi Lin, Yuan-Tzu Lan, Huann-Sheng Wang, Shung-Haur Yang, Wei-Shone Chen, Tzu-Chen Lin, Jeng-Kai Jiang, Shih-Ching Chang. FBXW7 mutation analysis and its correlation with clinicopathological features and prognosis in colorectal cancer patients. Int J Biol Markers 2015; 30(1): e88-e95.
5 2015 CHUNG?HSIN TSAI, JEN?HWEY CHIU, CHU?WEN YANG, JIR?YOU WANG, YI?FANG TSAI, LING?MING TSENG, WEI?SHONE CHEN and YI?MING SHYR. Molecular characteristics of recurrent triple-negative breast cancer. Mol Med Rep. 2015 Nov;12(5):7326-34.
6 2015 Kuo-Hung Huang, Yuan-Tzu Lan, Ming-Huang Chen, Yee Chao, Su-Shun Lo, Anna Fen-Yau Li, Chew-Wun Wu, Shih-Hwa Chiou, Muh-Hwa Yang, Yi-Ming Shyr, Wen-Liang Fang. The Correlation Between RhoA Expression and Clinicopathological Characteristics in Gastric Cancer Patients After Curative Surgery. World J Surg. 2015 ;39(9): 2289-99
7 2015 Li-Ching Fan, Hao-Wei Teng, Chung-Wai Shiau, Wei-Tien Tai, Man-Hsin Hung, Shung-Haur Yang, Jeng-Kai Jiang and Kuen-Feng Chen. Pharmacological Targeting SHP-1-STAT3 Signaling Is a Promising Therapeutic Approach for the Treatment of Colorectal Cancer. Neoplasia. 2015;17(9):687-696.
8 2016 Chang-Ching Yeh, Hsiao-Yun Tai, Hong Chou, Keh-Gong Wu, Horng-Der Shen. Vacuolar Serine Protease Is a Major Allergen of Fusarium proliferatum and an IgE-Cross Reactive Pan-Fungal Allergen. Allergy Asthma Immunol Res. 2016 ;8(5):438-44.
9 2016 Yi-Shin Huang, Li Yueh Wang, Chih-Hao Chang, Chin-Lin Perng and Han-Chieh Lin. Superoxide Dismutase 2 Genetic Variation as a Susceptibility Risk Factor for Alcoholic Cirrhosis. Alcohol and Alcoholism, 2016, 51(6) 633-637.
10 2016 Yu-Yao Chang, Pei-Ching Lin, Hung-Hsin Lin, Jen-Kou Lin, Wei-Shone Chen, Jeng-Kai Jiang, Shung-Haur Yang, Wen-Yih Liang, Shih-Ching Chang. Mutation spectra of RAS gene family in colorectal cancer. Am J Surg. 2016;212(3):537-544.
11 2016 Wen-Liang Fang, Kuo-Hung Huang, Yuan-Tzu Lan, Chien-Hsing Lin, Shih-Ching Chang, Ming-Huang Chen, Yee Chao, Wen-Chang Lin, Su-Shun Lo, Anna Fen-Yau Li, Chew-Wun Wu, Shih-Hwa Chiou, Yi-Ming Shyr. Mutations in PI3K/AKT pathway genes and amplifications of PIK3CA are associated with patterns of recurrence in gastric cancers. Oncotarget. 2016; 7(5):6201-20.
12 2016 Wen-Liang Fang, Yuan-Tzu Lan, Kuo-Hung Huang, Chien-An Liu, Yi-Ping Hung, Chien-Hsing Lin, Fang-Yu Jhang, Shih-Ching Chang, Ming-Huang Chen, Yee Chao, Wen-Chang Lin, Su-Shun Lo, Anna Fen-Yau Li, Chew-Wun Wu, Shih-Hwa Chiou and Yi-Ming Shyr. Clinical significance of circulating plasma DNA in gastric cancer. Int J Cancer. 2016; 138(12):2974-83. 
13 2016 Chih-Cheng Hsieh, Han-Shui Hsu, Shih-Ching Chang and Yann-Jang Chen. Circulating Cell-Free DNA Levels Could Predict Oncological Outcomes of Patients Undergoing Esophagectomy for Esophageal Squamous Cell Carcinoma. Int. J. Mol. Sci. 2016, 17, 2131.
14 2016 Matsushima S, Kuroda J, Zhai P, Liu T, Ikeda S, Nagarajan N, Oka S, Yokota T, Kinugawa S, Hsu CP, Li H, Tsutsui H, Sadoshima J. Tyrosine kinase FYN negatively regulates NOX4 in cardiac remodeling. J Clin Invest. 2016 Sep 1;126(9):3403-16.
15 2017 Ling-Ming Tseng, Jen-Hwey Chiu, Chun-Yu Liu, Yi-Fang Tsai, Yun-Lin Wang, Chu-Wen Yang, Yi-Ming Shyr. A comparison of the molecular subtypes of triple-negative breast cancer among non-Asian and Taiwanese women. Breast Cancer Res Treat. 2017 Jun;163(2):241-254.
16 2017 Yi-Fang Tsai, Ling-Ming Tseng, Chih-Yi Hsu, Muh-Hwa Yang, Jen-Hwey Chiu, Yi-Ming Shyr. Brain-derived neurotrophic factor (BDNF) -TrKB signaling modulates cancer-endothelial cells interaction and affects the outcomes of triple negative breast cancer. PLoS One. 2017 Jun 12;12(6):e0178173.
17 2017 Yuan-Tzu Lan, Ming-Huang Chen, Wen-Liang Fang, Chih-Cheng Hsieh, Chien-Hsing Lin, Fang-Yu Jhang, Shung-Haur Yang, Jen-Kou Lin, Wei-Shone Chen, Jeng-Kai Jiang, Pei-Ching Lin, Shih-Ching Chang. Clinical relevance of cell-free DNA in gastrointestinal tract malignancy. Oncotarget. 2017 10;8(2):3009-3017.
18 2017 Pao-Shu Wu, Yen-Hwa Chang & Chin-Chen Pan. High expression of heat shock proteins and heat shock factor-1 distinguishes an aggressive subset of clear cell renal cell carcinoma. Histopathology 2017, 71, 711-718.
19 2017 Chih-Yi Hsu, Hsiang-Ling Ho, Shih-Chieh Lin, Tiffany Dai-Hwa Ho, Donald Ming-Tak Ho. The MGMT promoter single-nucleotide polymorphism rs1625649 had prognostic impact on patients with MGMT methylated glioblastoma. PLoS One. 2017;12(10):e0186430.
20 2018 Peter Mu-Hsin Chang, Che-Hong Chen, Chi-Chun Yeh, Hsueh-Ju Lu, Tze-Tze Liu, Ming-Huang Chen, Chun-Yu Liu, Alexander T. H. Wu, Muh-Hwa Yang, Shyh-Kuan Tai, Daria Mochly-Rosen & Chi-Ying F. Huang. Transcriptome analysis and prognosis of ALDH isoforms in human cancer. Sci Rep. 2018; 8(1):2713.
21 2017 Muh-Lii Liang, Tsung-Han Hsieh, Yun-Ru Liu, Yi-Wei Chen, Yi-Yen Lee, Feng-Chi Chang, Shih-Chieh Lin, Ming-Chao Huang, Donald Ming-Tak Ho, TaiTong Wong, Yun Yen and Muh-Hwa Yang. Significance of cyclin D1 overexpression in progression and radio-resistance of pediatric ependymomas. Oncotarget. 2017 Dec 20;9(2):2527-2542.
22 2017 Yi-Chen Yeh, Hao-Jan Lei, Ming-Huang Chen, Hsiang-Ling Ho, Ling-Ya Chiu, Chung-Pin Li and Yu-Chao Wang. C-Reactive Protein (CRP) is a Promising Diagnostic Immunohistochemical Marker for Intrahepatic Cholangiocarcinoma and is Associated With Better Prognosis. Am J Surg Pathol. 2017;41(12):1630-1641.
23 2017 Lu TM, Lee TS, Lin SJ, Chan WL, Hsu CP. The prognostic value of asymmetric dimethylarginine in patients with cardiac syndrome X. PLos ONE.2017 Dec 5;12(12).
24 2018 謝明志、張世慶、李傳博、林植培. DR-70纖維蛋白原降解產物(FDP)腫瘤標誌應用於偵測大腸直腸癌原位癌(stage 0)之研究. 醫檢雜誌第三十三卷第二期, 2018 p1-p14.
25 2018 SAN?CHI CHEN, PETER MU?HSIN CHANG, HSIAO?JUNG WANG, SHYH?KUAN TAI, PEN?YUAN CHU and MUH?HWA YANG. PD?L1 expression is associated with p16INK4A expression in non?oropharyngeal head and neck squamous cell carcinoma. Oncol Lett. 2018; 15(2): 2259–2265.
26 2018 Chun-Yu Liu, Chia-Chi Hsu, Tzu-Ting Huang, Chia-Han Lee, Ji-Lin Chen, Shung-Haur Yang, Jeng-Kai Jiang, Wei-Shone Chen, Kuan-Der Lee and Hao-Wei Teng. ER stress-related ATF6 upregulates CIP2A and contributes to poor prognosis of colon cancer. Mol Oncol. 2018;12(10):1706-1717.
27 2018 Yen-Ying Chen, Hsiang-Ling Ho, Shih-Chieh Lin, Tiffany Dai-Hwa Ho and Chih-Yi Hsu. Upregulation of miR-125b, miR-181d, and miR-221 Predicts Poor Prognosis in MGMT Promoter-Unmethylated Glioblastoma Patients. Am J Clin Pathol. 2018;149(5):412-417.
28 2018 Kuo-Hung Huang, Wen-Liang Fang, Anna Fen-Yau Li, Po-Huang Liang, Chew-Wun Wu, Yi-Ming Shyr, Muh-Hwa Yang. Caspase-3, a key apoptotic protein, as a prognostic marker in gastric cancer after curative surgery. Int J Surg. 2018; 52: 258-263. 
29 2019 Yen-Ying Chen, Hsiang-Ling Ho, Shih-Chieh Lin, Chih-Yi Hsu, DonaldMing-Tak Ho. Loss of BCAT1 Expression is a Sensitive Marker for IDH-Mutant Diffuse Glioma. Neurosurgery. 2019:85(3):335-342.
30 2018 Chih-Cheng Hsieh, Han-Shui Hsu, Anna Fen-Yau Li, Yann-Jang Chen. Clinical relevance of PD-L1 and PD-L2 overexpression in patients with esophageal squamous cell carcinoma. J Thorac Dis. 2018; 10(7): 4433-4444.
31 2019 Ikeda S, Mizushima W, Sciarretta S, Abdellatif M, Zhai P, Mukai R, Fefelova N, Oka SI, Nakamura M, Del Re DP, Farrance I, Park JY, Tian B, Xie LH, Kumar M, Hsu CP, Sadayappan S, Shimokawa H, Lim DS, Sadoshima J. Hippo Deficiency Leads to Cardiac Dysfunction Accompanied by Cardiomyocyte Dedifferentiation During Pressure Overload. Circ Res. 2019 Jan 18;124(2):292-305.
32 2016 Chiao-Po Hsu, Jin-Feng Zhao, Shing-Jong Lin, Song-Kun Shyue, Bei-Chia Guo, Tse-Min Lu, Tzong-Shyuan Lee. Asymmetric Dimethylarginine Limits the Efficacy of Simvastatin Activating Endothelial Nitric Oxide Synthase. J Am Heart Assoc. 2016;5:e003327
33 2016 Chun-Yu Liu, Ming-Hung Hu, Chia-Jung Hsu, Chun-Teng Huang, Duen-Shian Wang, Wen-Chun Tsai, Yi-Ting Chen, Chia-Han Lee, Pei-Yi Chu, Chia-Chi Hsu, Ming-Huang Chen, Chung-Wai Shiau, Ling-Ming Tseng and Kuen-Feng Chen. Lapatinib inhibits CIP2A/PP2A/p-Akt signaling and induces apoptosis in triple negative breast cancer cells. Oncotarget. 2016 Feb; 7:9135-9149
34 2017 Chun-Yu Liu, Tzu-Ting Huang, Chun-Teng Huang, Ming-Hung Hu, Duen-Shian Wang, Wan-Lun Wang, Wen-Chun Tsai, Chia-Han Lee, Ka-Yi Lau, Hsiu-Ping Yang, Ming-Huang Chen, Chung-Wai Shiau, Ling-Ming Tseng, Kuen-Feng Chen. EGFR-independent Elk1/CIP2A signalling mediates apoptotic effect of an erlotinib derivative TD52 in triple-negative breast cancer cells. Eur J Cancer. 2017 Feb; 72:112-23.
35 2017 Ling-Ming Tseng, Jen-Hwey Chiu1, Chun-Yu Liu, Yi-Fang Tsai1, Yun-Lin Wang, Chu-Wen Yang, Yi-Ming Shyr. A comparison of the molecular subtypes of triple-negative breast cancer among non-Asian and Taiwanese women. Breast Cancer Res Treat. 2017 Jun;163(2):241-254.
36 2015 Szu-Yuan Li, Po-Hsun Huang, Der-Cherng Tarng, Tzu-Ping Lin, Wu-Chang Yang, Yen-Hwa Chang, An-Hang Yang, Chih-Ching Lin, Muh-Hwa Yang, Jaw-Wen Chen, Geert W. Schmid-Schönbein, Shu Chien, Pao-Hsien Chu and Shing-Jong Lin. Four-and-a-Half LIM Domains Protein 2 Is a Coactivator of Wnt Signaling in Diabetic Kidney Disease. JASN 2015, 26 (12) 3072-3084.
37 2016 Tzu-Ping Lin, Yi-Ting Chang, Sung-Yuan Lee, Mel Campbell, Tien-Chiao Wang, Shu-Huei Shen, Hsiao-Jen Chung, Yen-Hwa Chang, Allen W. Chiu, Chin-Chen Pan, Chi-Hung Lin, Cheng-Ying Chu, Hsing-Jien Kung, Chia-Yang Cheng, Pei-Ching Chang. REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling. Oncotarget. 2016;7(18):26137-51.
38 2018 Yi-Ting Chang, Tzu-Ping Lin, Jui-Ting Tang, Mel Campbelle, Yun-Li Luoa, Shih-Yen Lud, Chia-Pei Yang, Ting-Yu Chenga, Ching-Hsin Chang, Tze-Tze Liug, Chi-Hung Lin, Hsing-Jein Kung, Chin-Chen Pan, Pei-Ching Chang. HOTAIR is a REST-regulated lncRNA that promotes neuroendocrinedifferentiation in castration resistant prostate cancer. Cancer Lett. 2018;433:43-52.
39 2020 Yi-Chen Yeh, Hsiang-Ling Ho, Yu-Chung Wu, Chin-Chen Pan, Yu-Chao Wang, The-Ying Chou. AKT1 internal tandem duplications and point mutations are the genetic hallmarks of sclerosing pneumocytoma. Modem Pathology (2020) 33:391-403.
40 2020 Wei-An Lai, Chih-Yi Liu, Shih-Yao Lin, Chien-Chin Chen and Jen-Fan Hang. Characterization of Driver Mutations in Anaplastic Thyroid Carcinoma Identifies RAS and PIK3CA Mutations as Negative Survival Predictors. Cancers 2020, 12, 1973
41 2020 Chin-Chen Pan, Yi-Chen Yeh, Yu-Chao Wang & Yen-Hwa Chang. Differential expression analysis of clear cell renal cell carcinomas in The Cancer Genome Atlas distinguishes an aggressive subset enriched with chromosomes 7 and 12 gains. Histopathology 2020, 76, 950–958.
42 2020 Shiu-Feng Huang, Yhu-Chering Huang, Feng-Yee Chang, Jung-Chung Lin, Chun-Hsiang Chiu, Chien-Wen Chen, Fu-Der Wang, Yen-Ling Chiu, Shu-Hsing Cheng, Chien-Yu Cheng, Yi-Chun Lin, Cheng-Pin Chen, Chien-Hsien Huang, Po-Yu Liu, Yuan-Ti Lee, Chen-Hsiang Lee, Yao-Shen Chen, Cheng-Len Sy, Yu-Ting Tseng, Cheng-Ting Hsu, Chia-Chun Tseng, Yu-Lin Lee, Chun-Eng Liu, Huey-Kang Sytwu. Rapid establishment of a COVID-19 biobank in NHRI by National Biobank Consortium of Taiwan. Biomedical journal 43(2020) 314-317.
43 2021 Yun-Cheng Hsieh, Kuei-Chuan Lee, Hao-Jan Lei, Keng-Hsin Lan, Teh-Ia Huo, Yi-Tsung Lin, Che-Chang Chan, Bernd Schnabl, Yi-Hsiang Huang, Ming-Chih Hou and Han-Chieh Lin. (Pro)renin Receptor Knockdown Attenuates Liver Fibrosis Through Inactivation of ERK/TGF-b1/SMAD3 Pathway. Cellular and Molecular Gastroenterology and Hepatology 2021.
44 2019 Hsiang?Ling Ho, Teh?Ying Chou, Shung?Haur Yang, Jeng?Kai Jiang, Wei?Shone Chen, Yee Chao, Hao?Wei Teng. PD?L1 is a double?edged sword in colorectal cancer: the prognostic value of PD?L1 depends on the cell type expressing PD?L1. J Cancer Res Clin Oncol. 2019;145(7):1785-1794.
45 2022 Yu-Cheng Lee, Chih-Yi Hsu, Chiung-Ru Lai and Jen-Fan Hang. NTRK-Rearranged Papillary Thyroid Carcinoma Demonstrates Frequent Subtle Nuclear Features and Indeterminate Cytologic Diagnoses. Cancer Cytopathol. 2022;130:136-143.
46 2021 Shih-Yao Lin, Yeh-Han Wang, Chih-Yi Hsu, Yi-Jen Chen, Chiung-Ru Lai1 & Jen-Fan Hang. Analytical validation of human epidermal growth factor receptor 2 immunohistochemistry by the use of the A0485 antibody versus the 4B5 antibody and breast versus gastric scoring guidelines in ovarian clear cell carcinoma. Histopathology 2021, 79, 758–767.
47 2018 Chih-Chan Lee, Jiunn-Chang Lin, Wei-Lun Hwang, Ying-Ju Kuo, Hung-Kai Chen, Shyh-Kuan Tai, Chun-Chi Lin & Muh-Hwa Yang. Macrophage-secreted interleukin-35 regulates cancer cell plasticity to facilitate metastatic colonization. NATURE COMMUNICATIONS (2018) 9:3763.
48 2018 Chia-Hsin Hsieh, Shyh-Kuan Tai and Muh-Hwa Yang. Snail-overexpressing Cancer Cells Promote M2-Like Polarization of Tumor-Associated Macrophages by Delivering MiR-21-Abundant Exosomes. Neoplasia (2018) 20, 775–788.
49 2018 Yi-Ru Pan, Chih-Cheng Chen, Yu-Tien Chan, Hsiao-Jung Wang, Fan-Tso Chien, Yeng-Long Chen, Jing-Lan Liu & Muh-Hwa Yang. STAT3-coordinated migration facilitates the dissemination of diffuse large B-cell lymphomas. NATURE COMMUNICATIONS (2018) 9:3696.
50 2018 Ching-Fei Li, Jia-Yang Chen, Yang-Hui Ho, Wen-Hao Hsu, Liang-Chun Wu, Hsin-Yi Lan, Dennis Shin-Shian Hsu, Shyh-Kuan Tai, Ying-Chih Chang and Muh-Hwa Yang. Snail-induced claudin-11 prompts collective migration for tumour progression. Nature Cell Biology. 2019; 21:251-262.

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