姓名：郭清輝

科部：內科部新陳代謝科

聯絡方式

電話:8#1104

Email :    cfkwok@vghtpe.gov.tw

經歷：

1. 臺北榮民總醫院新藥臨床試驗中心主任2001/09~2009/05

2. 美國哈佛大學醫學院及喬斯林糖尿病中心博士後研究 1985/07~1987/06;

3. 臺北榮總內科部住院醫師1978/09～1983/06

研究方向：糖尿病的併發症; 胰島素作用

五年內研究著作:五年內論文

1. Chen CC, Lee TY, Kwok CF, Hsu YP, Shih KC, Lin YJ, Ho LT.  Major urinary protein 1 interacts with cannabinoid receptor type 1 in fatty acid-induced hepatic insulin resistance in a mouse hepatocyte model. Biochem Biophys Res Commun. 2015 May 15;460(4):1063-8. (IF:2.297)
2. Lin YJ, Juan CC, Kwok CF, Hsu YP, Shih KC, Chen CC, Ho LT. Endothelin-1 exacerbates development of hypertension and atherosclerosis in modest insulin resistant syndrome. Biochem Biophys Res Commun. 2015 May 8;460(3):497- 503. (IF:2.297)
3. Chang LH, Chu CH, Lin HD, Kwok CF, Won JG, Chen HS, Lin LY. The ankle brachial index is associated with prognosis in patients with diabetic kidney disease. Diabetes Res Clin Pract. 2015 May;108(2):316-22.(IF:2.538)
4. Kwok CF, Ho LT. Look Action for Health in Diabetes trial: What we have learned in terms of real world practice and clinical trials. J Diabetes Investig. 2014 Nov;5(6):637-8. (1^st author, IF:1.825)
5. Huang CJ, Kwok CF, Chou CH, Chou YC, Ho LT, Shih KC  The effect of exercise on lipid profiles and inflammatory markers in lean male adolescents: a prospective interventional study. J Investig Med. 2015 Jan;63(1):29-34. (IF:1.503)
6. Chang LH, Lin HD, Kwok CF, Won JG, Chen HS, Chu CH, Hwu CM, Kuo CS, Jap TS, Shih KC, Lin LY The combination of the ankle brachial index and brachial ankle pulse wave velocity exhibits a superior association with outcomes in diabetic patients. Intern Med. 2014;53(21):2425-31. (IF:0.904)
7. Lin YJ, Kwok CF, Juan CC, Hsu YP, Shih KC, Chen CC, Ho LT. Angiotensin II enhances endothelin-1-induced vasoconstriction through upregulating endothelin type A receptor. Biochem Biophys Res Commun. 2014 Aug 22;451(2):263-9. (IF 2.297)
8. Wang JS, Huang CN, Hung YJ, Kwok CF, Sun JH, Pei D, Yang CY, Chen CC, Lin CL, Sheu WH; Acarbose plus metformin fixed-dose combination outperforms acarbose monotherapy for type 2 diabetes-acarbose/metformin fixed-dose combination study investigators. Diabetes Res Clin Pract. 2013 Oct;102(1):16-24. (IF 2.538)
9. Shih KC, Hsieh SH, Kwok CF, Hwu CM, Hsieh PS, Ho LT. Effect of growth hormone on dawn phenomenon in patients with type 2 diabetes. Growth Factors. 2013 Apr;31(2):66-73. (co-correspondence,  IF: 3.386)
10. Wang CY, Lin CL, Huang TS, Chien MN, Hsieh SH, Huang YY, Shih KC, Tu ST, Chang CT, Chien-Ning H, Chou CW, Wu TJ, Liu RT, Lam HC, Kwok CF, Fu CC, Sheu WH. Inertia on hypoglycemia: highlight from a Taiwan subgroup analysis of Real-Life Effectiveness and Care Patterns of Diabetes Management (RECAP-DM) study. Diabetes Res Clin Pract. 2012 Oct;98(1):61-7. (IF 2.538)
11. Kwok CF, Ho LT. Severe hypoglycemia predicts major adverse outcomes in diabetic patients undergoing glycemic control regimes. J Diabetes Investig. 2012 Feb 20;3(1):34-5. (1^st author, IF: 1.825)
12. Huang JC, Lee TY, Liou MJ, Lin CM, Pei D, Chen ZC, Liu RT, Kwok CF. Begin with the real-world patients of non-goal-achieved hypercholesterolemia in taiwan through the ezetimibe/simvastatin tablet - The BRAVO Study. Curr Med Res Opin. 2011 Aug;27(8): 1645 -51. (correspondence, IF 2.653)
13. Hsu WY, Chao YW, Tsai YL, Lien CC, Chang CF, Deng MC, Ho LT, Kwok CF, Juan CC. Resistin induces monocyte-endothelial cell adhesion by increasing ICAM-1 and VCAM-1 expression in endothelial cells via p38MAPK-dependent pathway. J Cell Physiol. 2011 Aug;226(8):2181-8. (correspondence, IF3.839)
14. Chien Y, Lai YH, Kwok CF, Ho LT Endothelin-1 suppresses long-chain fatty acid uptake and glucose uptake via distinct mechanisms in 3T3-L1 adipocytes. Obesity (Silver Spring). 2011 Jan;19(1):6-12.(IF 3.734)

研究室成員：