TEL: +886-2-28757394
E-mail: shchiou@vghtpe.gov.tw

2014年

1. Bandey I, Chiou SH, Huang AP, Tsai JC, Tu PH. Progranulin promotes Temozolomide resistance of glioblastoma by orchestrating DNA repair and tumor stemness. Oncogene 2014. (SCI: 8.559)

2. Chiou SH, Jang SF, Mou CY. Mesoporous silica nanoparticles: a potential platform for generation of induced pluripotent stem cells? Nanomedicine 2014;9(4):377-380 (SCI: 5.824)

3. Cheng YH, Hung KH, Tsai TH, Lee CJ, Ku RY, Chiu AW, Chiou SH*, Liu CJ. Sustained delivery of latanoprost by thermosensitive chitosan-gelatin-based hydrogel for controlling ocular hypertension. Acta biomaterialia. 2014;10(10):4360-6 (SCI: 5.684)

4. Hsiao MH, Chiou SH, Larsson M, Hung KH, Wang YL, Liu CJ, Liu DM. A temperature-induced and shear-reversible assembly of latanoprost-loaded amphiphilic chitosan colloids: Characterization and in vivo glaucoma treatment. Acta biomaterialia 2014;10(7):3188-3196.(SCI: 5.684)

5. Tsai KL, Huang PH, Kao CL, Leu HB, Cheng YH, Liao YW, Yang YP, Chien Y, Wang CY, Hsiao CY, Chiou SH*, Chen JW, Lin SJ. Aspirin attenuates vinorelbine-induced endothelial inflammation via modulating SIRT1/AMPK axis. Biochemical pharmacology 2014;15(88(2)):189-200. (SCI: 4.65)

6. Lan YT, Chang SC, Yang SH, Lin CC, Wang HS, Jiang JK, Chen WS, Lin TC, Chiou SH, Lin JK. Comparison of clinicopathological characteristics and prognosis between early and late recurrence after curative surgery for colorectal cancer. American journal of surgery 2014;207(6):922-930. (SCI: 2.406)

7. How CK, Hou SK, Shih HC, Huang MS, Chiou SH, Lee CH, Juan CC. Expression Profile of MicroRNAs in Gram-Negative Bacterial Sepsis. Shock 2014. (SCI: 2.732)

8. Chang YC, Chang WC, Hung KH, Yang DM, Cheng YH, Liao YW, Woung LC, Tsai CY, Hsu CC, Lin TC, Liu JH, Chiou SH, Peng CH, Chen SJ. The generation of induced pluripotent stem cells for macular degeneration as a drug screening platform: identification of curcumin as a protective agent for retinal pigment epithelial cells against oxidative stress. Frontiers in aging neuroscience 2014;6(191):doi: 10.3389 (SCI: 2.843)

9. Liu YY, Li LF, Fu JY, Kao KC, Huang CC, Chien Y, Liao YW, Chiou SH, Chang YL. Induced Pluripotent Stem Cell Therapy Ameliorates Hyperoxia-Augmented Ventilator-Induced Lung Injury through Suppressing the Src Pathway. PLoS One. 2014;9(10):e109953 (SCI: 3.534)

10. Fang IM, Yang CH, Chiou SH*, Yang CM.. Induced Pluripotent Stem Cells Without c-Myc Ameliorate Retinal Oxidative Damage via Paracrine Effects and Reduced Oxidative Stress in Rats. Journal of ocular pharmacology and therapeutic 2014. (SCI: 1.420)

11. Chan PC, Wu CY, Chou LS, Ho CH, Chang CW, Chiou SH, Lin WJ, Chen FD, Chang CA, Hwang JJ, Liu RS, Wang HE. Monitoring Tumor Response After Histone Deacetylase Inhibitor Treatment Using 3'-Deoxy-3'-[18F]-fluorothymidine PET. Mol Imaging Biol. 2014. (SCI: 2.869)

12. Lee, YY ; Yang, YP ; Huang, MC ; Wang, ML ; Yen, SH ; Huang, PI ; Chen, YW ; Chiou SH; Lan, YT ; Ma, HI ; Shih, YH ; Chen, MT. MicroRNA142-3p Promotes Tumor-Initiating and Radioresistant Properties in Malignant Pediatric Brain Tumors. Cell transplantation 2014;23(4-5):669-690. (SCI: 3.570)

13. Liu WH, Chang YL, Lo WL, Li HY, Hsiao CW, Peng CH, Chiou SH, Ma HI, Chen SJ.. Human Induced Pluripotent Stem Cell and Nanotechnology-Based Therapeutics. Cell transplantation 2014. (SCI: 3.570)

14. Ju SY, Chiou SH, Su Y. Maintenance of the stemness in CD44(+) HCT-15 and HCT-116 human colon cancer cells requires miR-203 suppression. Stem Cell Research 2014;44(1):86-100.(SCI: 3.912)

15. Wu CY, Chan PC, Chou LS, Chang CW, Yang FY, Liu RS, Chiou SH, Chen YW, Yen SH, Wang HE. Pulsed-focused ultrasound enhances boron drug accumulation in a human head and neck cancer xenograft-bearing mouse model. Molecular Imaging and Biology 2014;16(1):95-101. (SCI: 2.869)

16. Huang KH, Lan YT, Fang WL, Chen JH, Lo SS, Li AF, Chiou SH, Wu CW, Shyr YM.. Comparison of the Operative Outcomes and Learning Curves between Laparoscopic and Robotic Gastrectomy for Gastric Cancer. PLoS One 2014;9(10):e111499. (SCI: 3.534)

 

2013年

17. Larssona M, Huanga WC, Hsiao MH, Wang YJ, Nyden M, Chiou SH, Liu DM. Biomedical applications and colloidal properties of amphiphilically modified chitosan hybrids. Progress in Polymer Science 38 (2013) 1307– 1328 (IF=26.383).

18. Chiou GY, Chien CS, Wang ML, Chen MT, Yang YP, Chien Y, Chang YC, Shen CC, Chio CC, Lu KH, Ma HS, Yu YL, Chen KH, Liu DM, Miller SA, Chen YW, Huang PI, Shih YH, Hung MC*, Chiou SH*. Epigenetic Regulation of the MiR142-3p/ Interleukin-6 Circuit in Glioblastoma. Molecular Cell  2013 Dec 12;52(5):693-706. (SCI: 15.28)

19. Chen W, Tsai PH, Hung Y, Chiou SH*, Mou CY*. A Non-Viral Cell Labeling and Differentiation Agent for Induced Pluripotent Stem Cells Based on Mesoporous Silica Nanoparticles. ACS Nano. 2013 Oct 22;7(10):8423-40. (SCI: 12.062)

20. Chiou SH*, Jiang BH, Yu YL, Chou SJ, Ping-Hsing Tsai, Chang WC, Chen LK, Chen LH, Yueh Chien Y, Chiou GY. Poly(ADP-ribose) Polymerase 1 Regulates Nuclear Reprogramming and Promotes iPSC Generation without c-Myc. J Exp Med. 2013 Jan. 14;210(1):85-98. (SCI:13.853; Medicine, Research & Experimental 2/112)

21. Yu CC, Tsai LL, Wang ML, Yu CH, Lo WL, Chang YC, Chiou GY, Chou MY, Chiou SH*. miR145 targets the SOX9/ADAM17 axis to inhibit tumor initiating cells and IL-6-mediated paracrine effects in head and neck cancer. Cancer Res. 2013 Jun 1;73(11):3425-3440. (IF=8.565)

22. Li LF, Liu YY, Yang CT, Chien Y, Wang ML, Twu NF, Wang CY, Chung-Chi Huang CC, Kao KC, Hsu HS, Chiou SH*. Improvement of ventilator-induced lung injury by iPSCs-derived Conditioned Medium via Inhibiting PI3K/Akt Pathway and an IP-10-related Mechanism. Biomaterials. 2013 Jan;34(1):78-91. (IF=7.602)

23. Ju SY, Chiou SH*, Su Y*. Maintenance of the stemness in CD44₊ HCT-15 and HCT-116 human colon cancer cells requires miR-203 suppression. Stem Cell Res. 2013 Oct 2;12(1):86-100.

24. Lee YR, Yu DS, Liang YC, Huang KF, Chou SJ, Chen TC, Lee CC, Chen CL, Chiou SH *, Huang HS*. New approaches of PARP-1 inhibitors in human lung cancer cells and cancer stem-like cells by some selected anthraquinone-derived small molecules. PLoS One. 2013;8(2):e56284.

25. Liu YY, Li LF, Yang CT, Lu KH, Huang CC, Kao KC, Chiou SH*. Suppressing NF-κB and NKRF Pathways by Induced Pluripotent Stem Cell Therapy in Mice with Ventilator-Induced Lung Injury. PLoS One. 2013 Jun 26;8(6):e66760.

26. Fang IM, Yang CM, Yang CH*, Chiou SH*, Chen MS. Transplantation of induced pluripotent stem cells without C-Myc attenuates retinal ischemia and reperfusion injury in rats. Exp Eye Res. 2013 May 28;113C:49-59.

2012年

27. Wang ML, Pan CM, Chiou SH, Chen WH, Chang HY, Lee OK, Hsu HS, Wu CW. Oncostatin m modulates the mesenchymal-epithelial transition of lung adenocarcinoma cells by a mesenchymal stem cell-mediated paracrine effect. Cancer Res. 2012 Nov 15;72(22):6051-64. (IF=8.565)

28. Lin SP, Lee YT, Wang JY, Miller SA, Chiou SH, Hung MC, Hung SC. Survival of Cancer Stem Cells under Hypoxia and Serum Depletion via Decrease in PP2A Activity and Activation of p38-MAPKAPK2-Hsp27. PLoS One. 2012;7(11):e49605. (IF=3.82)

29. Yu YH, Chiou GY, Huang PI, Lo WL, Wang CY, Lu KH, Yu CC, Alterovitz G, Huang WC, Lo JF, Hsu HS, Chiou SH*. Network Biology of Tumor Stem-like Cells Identified a Regulatory Role of CBX5 in Lung Cancer. Sci Rep. 2012;2:584.

30. Chu PM, Ma HI, Chen LH, Chen MT, Huang PI, Lin SZ, Chiou SH*. Deregulated microRNAs identified in isolated glioblastoma stem cells - An overview. Cell Transplant. 2012 Nov 1. (IF=4.02)

31. Chan CC, Cheng LY, Lu J, Huang YH, Chiou SH (Co-corresponding author)*, Tsai PH, Huo TI, Lin HC, Lee FY. The role of interferon-γ inducible protein-10 in a mouse model of acute liver injury post induced pluripotent stem cells transplantation. PLoS One. 2012;7(12):e50577.

32. Huang PI, Lo WL, Cherng JY, Chien Y, Chiou GY, Chiou SH*. Non-viral delivery of RNA interference targeting cancer cells in cancer gene therapy. Curr Gene Ther. 2012 Aug 1;12(4):275-84.(IF=3.386)

33. Chien Y, Liao YW, Liu DM, Lin HL, Chen SJ, Chen HL, Peng CH, Liang CM, Mou CY, Chiou SH*. Corneal repair by human corneal keratocyte- reprogrammed iPSCs and amphiphatic carboxymethyl-hexanoyl chitosan hydrogel. Biomaterials. 2012 Nov;33(32):8003-16.(IF=7.404)

34. Chou YT, Hsieh CH, Chiou SH(Co-Fist author), Hsu CF, Kao YR, Lee CC, Chung CH, Wang YH, Hsu HS, Pang ST, Shieh YS, Wu CW. CITED2 functions as a molecular switch of cytokine-induced proliferation and quiescence. Cell Death Differ. 2012 Jul 20. [Epub ahead of print](IF=8.849)

35. Ding DC, Shyu WC, Lin SZ, Liu HW, Chiou SH*, Chu TY*. Human umbilical cord mesenchymal stem cells support non-tumorigenic expansion of human embryonic stem cells. Cell Transplant. 2012 Jun 20.

36. Chang YL, Chen SJ, Kao CL, Hung SC, Ding DC, Yu CC, Chen YJ, Ku HH, Lin CP, Lee KH, Chen YC, Wang JJ, Hsu CC, Chen LK, Li HY, Chiou SH*. Docosahexaenoic acid promotes dopaminergic differentiation in induced pluripotent stem cells and inhibits teratoma formation in rats with Parkinson-like pathology. Cell Transplant. 2012;21(1):313-32.

37. Lo WL, Chien Y, Chiou GY, Tseng LM, Hsu HS, Chang YL, Lu KH, Chien CS, Wang ML, Chen YW, Huang PI, Hu FW, Yu CC, Chu PY, Chiou SH*. Nuclear localization signal-enhanced RNA interference of EZH2 and Oct4 in the eradication of head and neck squamous cell carcinoma-derived cancer stem cells. Biomaterials. 2012;33:3693-709. (IF=7.404)

38. Chiou GY, Cherng JY, Hsu HS, Wang ML, Tsai CM, Lu KH, Chien Y, Hung SC, Chen YW, Wong CI, Tseng LM, Huang PI, Yu CC, Hsu WH, Chiou SH*. Cationic polyurethanes-short branch PEI-mediated delivery of Mir145 inhibited epithelial-mesenchymal transdifferentiation and cancer stem-like properties and in lung adenocarcinoma. J Control Release. 2012 Apr 30;159(2):240-50.(IF=6.499)

39. Chu PM, Chen LH, Chen MT, Ma HI, Su TL, Hsieh PC, Chien CS, Jiang BH, Chen YC, Lin YH, Shih YH, Tu PH, Chiou SH*. Targeting autophagy enhances BO-1051-induced apoptosis in human malignant glioma cells. Cancer Chemother Pharmacol. 2012;69:621-33. (IF=2.833)

40. Yang YP, Chien Y, Chiou GY, Cherng JY, Wang ML, Lo WL, Chang YL, Huang PI, Chen YW, Shih YH, Chen MT, Chiou SH*. Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI. Biomaterials. 2012 Feb;33(5):1462-76.(IF=7.404)

2011年

41. Peng CH, Cherng JY, Chiou GY, Chen YC, Chien CH, Kao CL, Chang YL, Chien Y, Chen LK, Liu JH, Chen SJ, Chiou SH*. Delivery of Oct4 and SirT1 with cationic polyurethanes-short branch PEI to aged retinal pigment epithelium. Biomaterials. 2011 Dec;32(34):9077-88. (IF=7.404)

42. Yang KY, Shih HC, How CK, Chen CY, Hsu HS, Yang CW, Lee YC, Perng RP, Peng CH, Li HY, Chang CM, Mou CY, Chiou SH*. IV delivery of induced pluripotent stem cells attenuates endotoxin-induced acute lung injury in mice. Chest. 2011;140:1243-53.(IF=5.250)

43. Li HY, Chien Y, Chen YJ, Chen SF, Chang YL, Chiang CH, Jeng SY, Chang CM, Wang ML, Chen LK, Hung SI, Huo TI, Lee SD, Chiou SH*. Reprogramming induced pluripotent stem cells in the absence of c-Myc for differentiation into hepatocyte-like cells .Biomaterials. 2011 Sep;32(26):5994-6005. (IF=7.404)

44. Tsai KS, Yang SH, Lei YP, Tsai CC, Chen HW, Hsu CY, Chen LL, Wang HW, Miller SA, Chiou SH, Hung MC, Hung SC. Mesenchymal stem cells promote formation of colorectal tumors in mice. Gastroenterology. 2011 Sep;141(3):1046-56. (IF=11.675)

45. Hwang WL, Yang MH, Tsai ML, Lan HY, Su SH, Chang SC, Teng HW, Yang SH, Lan YT, Chiou SH*, Wang HW*. SNAIL regulates interleukin-8 expression, stem cell-like activity, and tumorigenicity of human colorectal carcinoma cells. Gastroenterology. 2011 Jul;141(1):279-91, 291.e1-5. Epub 2011 Apr 16. (IF=11.675)

46. Lo WL, Yu CC, Chiou GY, Chen YW, Huang PI, Chien CS, Tseng LM, Chu PY, Lu KH, Chang KW, Kao SY, Chiou SH*. MicroRNA-200c attenuates tumour growth and metastasis of presumptive head and neck squamous cell carcinoma stem cells. J Pathol. 2011 Mar;223(4):482-95. (IF=6.318)

47. Chiou SH*, Chen SJ, Chang YL, Chen YC, Li HY, Chen DT, Wang HH, Chang CM, Chen YJ, Ku HH. MafA promotes the reprogramming of placenta-derived multipotent stem cells into pancreatic islets-like and insulin cells. J Cell Mol Med. 2011 Mar;15(3):612-24. (IF=4.125)

48. Chen LH, Loong CC, Su TL, Lee YJ, Chu PM, Tsai ML, Tsai PH, Tu PH, Chi CW, Lee HC, Chiou SH*. Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway. Biochem Pharmacol. 2011 Mar 1;81(5):594-605. (IF=4.705)

49. Lo JF, Yu CC, Chiou SH, Huang CY, Jan CI, Lin SC, Liu CJ, Hu WY, Yu YH. The epithelial-mesenchymal transition mediator S100A4 maintains cancer-initiating cells in head and neck cancers. Cancer Res. 2011 Mar 1;71(5):1912-23.(IF=7.856)

50. Wang CH, Chiou SH(Equal to co-first), Chou CP, Chen YC, Huang YJ, Peng CA. Photothermolysis of glioblastoma stem-like cells targeted by carbon nanotubes conjugated with CD133 monoclonal antibody. Nanomedicine-Nanotechnology Biology and Medicine 2011 Feb;7(1):69-79. (IF=6.930)

51. Li HY, Liao CY, Lee KH, Chang HC, Chen YJ, Chao KC, Chang SP, Cheng HY, Chang CM, Chang YL, Hung SC, Sung YJ, Chiou SH*. Collagen IV significantly enhances migration and transplantation of embryonic stem cells: involvement of α2β1 integrin-mediated actin remodeling. Cell Transplant. 2011;20(6):893-907.

2010年

52. Chiou SH, Wang ML, Chou YT, Chen CJ, Hong CF, Hsieh WJ, Chang HT, Chen YS, Lin TW, Hsu HS, Wu CW. Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation. Cancer Res. 2010 Dec 15;70(24):10433-44. (IF=7.856)

53. Chen YW, Chen KH, Huang PI, Chen YC, Chiou GY, Lo WL, Tseng LM, Hsu HS, Chang KW, Chiou SH*. Cucurbitacin I suppressed stem-like property and enhanced radiation-induced apoptosis in head and neck squamous carcinoma--derived CD44(+)ALDH1(+) cells. Mol Cancer Ther. 2010 Nov;9(11):2879-92. (IF=5.226)

54. Chen SJ, Chang CM, Tsai SK, Chang YL, Chou SJ, Huang SS, Tai LK, Chen YC, Ku HH, Li HY, Chiou SH*. Functional improvement of focal cerebral ischemia injury by subdural transplantation of induced pluripotent stem cells with fibrin glue. Stem Cells Dev. 2010 Nov;19(11):1757-67. (IF=4.459)

55. Chen LH, Chiou GY, Chen YW, Li HY, Chiou SH*. MicroRNA and aging: a novel modulator in regulating the aging network. Ageing Res Rev. 2010 Nov;9 Suppl 1:S59-66. (IF=6.174)

56. Chen YJ, Li HY, Chang YL, Yuan CC, Tai LK, Lu KH, Chang CM, Chiou SH*. Suppression of migratory/invasive ability and induction of apoptosis in adenomyosis-derived mesenchymal stem cells by cyclooxygenase-2 inhibitors. Fertil Steril. 2010 Nov;94(6):1972-9. (IF=3.775)