Some images has been designed using resources from Unsplash & Pixabay & Pexels & Freepik and some icons from Flaticon


TEL: +886-2-28712121 Ext. 1292



1993 ~ 2000


2008 ~ 2014

美國哈佛大學/麻省理工學院博士     (Harvard-MIT Division of Health Sciences and Technology)



2001 ~ 2006




2006 ~ 2008


2011 ~ 2016


2017 ~ 迄今 台北榮民總醫院醫學研究部主治醫師
2017 ~ 迄今 台北榮民總醫院耳鼻喉頭頸醫學部主治醫師
2023 ~ 迄今 國立陽明交通大學醫學院教授
2023 ~ 迄今 國立陽明交通大學腦科學研究所/臨床醫學研究所 合聘教授
  1. 聽覺生理學及基因醫學
  2. 遺傳性疾病的基因療法
  3. 耳鼻喉頭頸外科精準醫療
  4. 聽覺智慧醫療
  1. Lin HYH, Lai HS, Huang CY, Chen CH, Wu SL, Chu YC, Chen YF, Lai YH, Cheng YF*. Smartphone-bundled Earphones as Personal Sound Amplification Products in Adults with Sensorineural Hearing Loss. iScience. 2022 Dec; 25(12):105042 (*Corresponding author)
  2. Cheng YF, Xirasagar S, Kuo NW, Lin HC. Tinnitus and risk of attempted suicide: A one year follow-up study. J Affect Disord. 2022 Nov 10;322:141-145.
  3. Lu YC, Tsai YH, Chan YH, Hu CJ, Huang CY, Xiao R, Hsu CJ, Vandenberge LH, Wu CC*, Cheng YF*. Gene therapy with a synthetic adeno-associated viral vector improves audiovestibular phenotypes in Pjvk mutant mice. JCI Insight. 2022 Oct 24;7(20):e152941 (*Co-Corresponding author) (Cover Story)
  4. Chen YC, Chu YC, Huang CY, Lee YT, Lee WY, Hsu CY, Yang AC, Liao WH, Cheng YF*. Smartphone-based artificial intelligence using a transfer learning algorithm for the detection and diagnosis of middle ear diseases : a retrospective deep learning study. EClinicalMedicine. 2022 Jul 12;51:101543 (*Co-Corresponding author)
  5. Chen CH, Huang CY, Cheng HL, Lin HYH, Chu YC, Chang CY, Lai YH, Wang MC, Cheng YF*. Comparison of personal sound amplification products and conventional hearing aids for patients with hearing loss: A systematic review with meta-analysis. EClinicalMedicine. 2022 Apr 7;46(4):101378. (*Corresponding author)
  6. Chen CH, Huang CY, Cheng HL, Lin HH, Chu YC, Chang CY, Lai YH, Wang MC, Cheng YF*. Smartphone-Enabled versus Conventional Otoscopy in Detecting Middle Ear Disease: A Meta-Analysis. Diagnostics. 2022 Apr 13;12(4):972.  (*Corresponding author)
  7. Ting KC, Chang CC, Huang CY, Chen YF, YF Cheng*. Are Electrocochleographic Changes an Early Sign of Cochlear Synaptopathy? A Prospective Study in Tinnitus Patients with Normal Hearing. Diagnostics. 2022 Mar 25;12(4): 802. (*Corresponding author)
  8. Huang CY, Li SD, Tsia MH, Chen CH, Cheng YF*. The Impact of Acute Tinnitus on Listening Effort: A Study Based on Clinical Observations of Sudden Sensorineural Hearing Loss Patients. Int J Environ Res Public Health. 2022. Mar 19;19(6):3661 (*Corresponding author)
  9. Hu CJ, Lu YC, Tsai YH, Lin PH, Lee YS, Yu IS, Lin SW, Liu TC, Hsu CJ, Yang TH, Cheng YF*, Wu CC*. Insights into phenotypic differences between humans and mice with p.T721M and other C-terminal variants of the SLC26A4 gene. Sci Rep. 2021 Oct 25;11(1):20983. (*Co-Corresponding author)
  10. Chen CH, Lin HYH, Wang MC, Chang CY, Huang CY, Cheng YF*. Diagnostic Accuracy of Smartphone-based Audiometry for Hearing Loss Detection: A Meta‐analysis. JMIR Mhealth Uhealth. 2021 Sep 10;9(9):e28378. (*Corresponding author)
  11. Chen CH, Huang CY, Lin HYH, Wang MC, Chang CY, Cheng YF*. Association of Sodium Thiosulfate with Risk of Ototoxic Effects from Platinum-based Chemotherapy: A Systematic Review and Meta-analysis. JAMA Network Open. 2021 Aug 2 ;4(8):e2118895. (*Corresponding author)
  12. Hsueh CY, Huang CY, Yang CF, Chang CC, Lin WS, Cheng HL, Wu SL, Cheng YF*, Niu DM*. Hearing characteristics of infantile‑onset Pompe disease after early enzyme‑replacement therapy. Orphanet J Rare Dis. 2021 Aug 5;16(1):348 (*Co-Corresponding author)
  13. Cheng YF, Xirasagar S, Yang TH, Wu CS, Kuo NW,Shia BC, Lin HC. Risk of Early-Onset Dementia Among Persons with Tinnitus – A Retrospective Case-Control Study. Sci Rep. 2021 Jun 28;11(1):13399.
  14. Hu CJ, Lu YC, Yang TH, Chan YH, Tsai CY, Yu IS, Lin SW, Liu TC, Cheng YF*, Wu CC, Hsu CJ. Toward the Pathogenicity of the SLC26A4 p.C565Y Variant Using a Genetically Driven Mouse Model. Int J Mol Sci. 2021 Mar; 22(6): 2789 (*Co-corresponding author)
  15. Chen CH, Huang CY, Chang CY, Cheng YF*. Efficacy of Low-Level Laser Therapy for Tinnitus: A Systematic Review with Meta-Analysis and Trial Sequential Analysis. Brain Sci. 2020 Dec 2;10(12):E931. (*Corresponding author)
  16. Chen YC, Huang CY, Lee YT, Wu CH, Chang SK, Cheng HL, Chang PH, Niu DM*, Cheng YF*. Audiological and otologic manifestations of glutaric aciduria type I. Orphanet J Rare Dis. 2020 Dec 1;15(1):337. (*Co-Corresponding author)
  17. Lin HYH, Chu YC, Lai YH, Cheng HL, Lai FP, Cheng YF*, Liao WH. A Smartphone-Based Approach to Screening for Sudden Sensorineural Hearing Loss: A Cross-sectional Validity Study. JMIR Mhealth Uhealth. 2020 Nov 11;8(11):e23047. (*Co-corresponding author)
  18. Cheng YF, Tsai YH, Huang CY, PC Chang, YH Lee, Lu YC, Hsu CC, Wu CC. Generation and pathological characterization of a transgenic mouse model carrying a missense PJVK mutation. Biochem Biophy Res Commun. 2020 Nov 19;532(4):675-681
  19. Hu CJ, Lu YC, Tsai YH, Cheng HY, Takeda H, Huang CY, Xiao R, Hsu CJ, Tsai JW, Vandenberghe LH, Wu CC, Cheng YF*. Efficient in utero gene transfer to the mammalian inner ears by the synthetic adeno-associated viral vector Anc80L65. Mol Ther Methods Clin Dev. 2020 Jun 24;18:493-500. (*Corresponding author) (Cover Story)
  20. Cheng YF, Xirasagar S, Yang TH, Wu CS, Kao YW, Shia BC, Lin HC. Increased Risk of Tinnitus Following a Trigeminal Neuralgia Diagnosis: A One-year Follow-up Study. 2020 May 6;21(1):46. J Headache Pain. 2020 May 6;21(1):46.
  21. Chen YC, Huang CY, Kuo YJ, Cheng HL, Cheng YF*, Liao WH. Developing a novel meatal areolar tissue autograft for minimally invasive tympanoplasty. J Chin Med Assoc. 2020 Oct;83(10):956-961 (*Co-Corresponding author)
  22. Huang CY, Tsai YH, Tsai YC, Chan YC, Chiou SH, Wu CC, Cheng YC*. Establishment of an induced pluripotent stem cell (iPSC) line from a 7-year-old male patient with profound hearing loss carrying c.235delC in GJB2 gene. Stem Cell Research, 2020 May;45:101795. (*Corresponding author)
  23. Cheng YF, Chan YH, Hu CJ, Lu YC, Fujioka M, Okano H, Hsu CJ, Chang KH, Wu CC. Generation of a human iPS cell line (CGMH.SLC26A4919-2) from a Pendred Syndrome patient carrying SLC26A4 c.919-2A>G splice-site mutation. Stem Cell Res. 2019 Oct;40:101524.
  24. Shen J, Oza AM, Del Castillo I, Duzkale H, Matsunaga T, Pandya A, Kang HP, Mar-Heyming R, Guha S, Moyer K, Lo C, Kenna M, Alexander JJ, Zhang Y, Hirsch Y, Luo M, Cao Y, Wai Choy K, Cheng YF, Avraham KB, Hu X, Garrido G, Moreno-Pelayo MA, Greinwald J, Zhang K, Zeng Y, Brownstein Z, Basel-Salmon L, Davidov B, Frydman M, Weiden T, Nagan N, Willis A, Hemphill SE, Grant AR, Siegert RK, DiStefano MT, Amr SS, Rehm HL, Abou Tayoun AN; ClinGen Hearing Loss Working Group.Consensus interpretation of the Met34Thr and Val37Ile variants in GJB2 by the ClinGen Hearing Loss Expert Panel. Genet Med. 2019 Nov;21(11):2442-2452.
  25. Wu CC, Tsai CY, Lin YH, Chen PY, Lin PH, Cheng YF, Wu CM, Lin YH, Lee CY, Erdenechuluun J, Liu TC, Chen PL, Hsu CJ. Genetic Epidemiology and Clinical Features of Hereditary Hearing Impairment in the Taiwanese Population. Genes. 2019 Oct 1;10(10).
  26. Chu YC*, Cheng YF*, Lai YH, Tsao Y, Tu TY, Young ST, Chen TS, Chung YF, Lai F, Liao WH. A Smartphone-Based Approach for Hearing Screening of School-age Children: A Cross-sectional Validation Study. JMIR Mhealth Uhealth, 2019 Apr 1;7(4):e12033. (* equal contribution)
  27. Cheng YF, Chu YC, Tu TY, Shiao AS, We SL, Liao WH. Modified Siegel's criteria for sudden sensorineural hearing loss: Reporting recovery outcomes with matched pretreatment hearing grades. J Chin Med Assoc. 2018 Nov;81(11): 1008-1012
  28. Cheng YF, Tong M, Edge ASB. “Destabilization of Atoh1 by E3 ubiquitin ligase Huwe1 and casein kinase 1 is essential for normal sensory hair cell development”. J Bio Chem. 2016;291:21096-21109