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許瀚水 教授                                                                   


許瀚水 教授
Han-Shui Hsu, MD, PhD.  

學歷  進修



經歷 專科醫師證書

 台灣胸腔外科醫學會秘書長                                                台灣胸腔外科醫學會理事長                                                台灣胸腔外科醫學會名譽理事長

 胸腔超音波專業醫師                                                           達文西機器手臂輔助 胸腔外科手術醫師證書                       Member of American Society of Thoracic Surgeon
   Menber of International Society of Surgery




  1. Tu CC, Hsu PK, Chien LI, Liu WC, Huang CS, Hsieh CC, Hsu HS, Wu YC. Prognostic histological factors in patients with esophageal squamous cell carcinoma after preoperative chemoradiation followed by surgery. BMC Cancer. 2017 Jan 19;17(1):62.
  2. Hsu PK, Chen HS, Huang CS, Liu CC, Hsieh CC, Hsu HS, Wu YC, Wu SC. Patterns of recurrence after oesophagectomy and postoperative chemoradiotherapy versus surgery alone for oesophageal squamous cell carcinoma. Br J Surg. 2017 Jan;104(1):90-97.
  3. Guo JY, Hsu HS, Tyan SW, Li FY, Shew JY, Lee WH, Chen JY. Serglycin in tumor microenvironment promotes non-small cell lung cancer aggressiveness in a CD44-dependent manner. Oncogene. 2017 Apr 27;36(17):2457-2471.
  4. Tsung YC, Chung CY, Wan HC, Chang YY, Shih PC, Hsu HS, Kao MC, Huang CJ.Dimethyl Sulfoxide Attenuates Acute Lung Injury Induced by Hemorrhagic Shock/Resuscitation in Rats. Inflammation. 2017 Apr;40(2):555-565.
  5. Yen-Chiang Tseng, Yen-Han Tseng, Hua-Lin Kao, Chih-Cheng Hsieh, The-Ying Chou, Yih-Gang Goan, Wen-Hu Hsu, Han-Shui Hsu*. Long term oncological outcome of thymoma and thymic carcinoma- an analysis of 235 cases from a single institution. Plos one, 2017 Jun 20;12(6):e0179527. doi: 10.1371/journal.pone.0179527. eCollection 2017.
  6. Hsu PK, Chen HS, Liu CC, Huang CS, Hsieh CC, Hsu HS, Wu SC. Pre- versus postoperative chemoradiotherapy for locally advanced esophageal squamous cell carcinoma. J Thorac Cardiovasc Surg. 2017 Aug;154(2):732-740.
  7. Hsu HS*, Liu CC, Lin JH, Hsu TW, Hsu JW, Su K, Hung SC. Involvement of ER stress, PI3K/AKT activation, and lung fibroblast proliferation in bleomycin-induced pulmonary fibrosis. Sci Rep. 2017 Oct 27;7(1):14272. doi: 10.1038/s41598-017-14612-5.
  8. Chen-Chi Liu, Jiun-Han Lin, Tien-Wei Hsu, Jyuan-Wei Hsu, Jer-Wei Chang, Kelly Su, Han-Shui Hsu*, Shih-Chieh Hung. Collagen XVII/Laminin-5 Activates Epithelial-to-Mesenchymal Transition and Is Associated with Poor Prognosis in Lung Cancer. Oncotarget 2018 Jan 5;9(2):1656-1672(Correspondence Author).
  9. Chiu YJ, Yang JS, Hsu HS, Tsai CH, Ma H. Adipose-derived stem cell conditioned medium attenuates cisplatin-triggered apoptosis in tongue squamous cell carcinoma. Oncol Rep. 2018 Feb;39(2):651-658.                      
  10. Chih-Cheng Hsieh, Han-Shui Hsu, Anna Fen-Yau Li, Yann-Jang Chen.Clinical relevance of PD-L1 and PD-L2 overexpression in patients with esophageal squamous cell carcinoma. J Thorac Dis. 2018 Jul;10(7):4433-4444.
  11. Po-Kuei Hsu, Ling-I Chien, Chih-Hung Lin, Yi-Chen Yeh, Cheng-Yen Chuang, Han-Shui Hsu, Yu-Chung Wu, Chung-Ping Hsu. Impact of perineural invasion as a histopathological prognostic factor in ypStage II/III oesophageal squamous cell carcinomat.Eur J Cardiothorac Surg. 2019 May 1;55(5):927-933.
  12. Chou KT, Cheng SC, Huang SF, Perng DW, Chang SC, Chen YM, Hsu HS, Hung SC. Impact of Intermittent Hypoxia on Sepsis Outcomes in a Murine Model. Sci Rep. 2019 Sep 9;9(1):12900. doi: 10.1038/s41598-019-49381-w.
  13. Chen‐Chi Liu Kun‐Ta Chou   Jyuan‐Wei Hsu   Jiun‐Han Lin   Tien‐Wei Hsu David Hung‐Tsang Yen   Shih‐Chieh Hung   HanShui Hsu*. High metabolicrate and stem cell characteristics of esophageal cancer stem-like cells depend on the Hsp27-AKT-HK2 pathway.Int J Cancer. 2019 Oct 15;145(8):2144-2156.
  14. Yi-Ying Lee , Po-Kuei Hsu , Chien-Sheng Huang , Yu-Chung Wu and Han-Shui Hsu.Complications after Chest Tube Removal and Reinterventions in Patients with Digital Drainage.Systems.J Clin Med. J Clin Med. 2019 Dec 1;8(12):2092.
  15. Cheng IY, Liu CC, Lin JH, Hsu TW, Hsu JW, Li AF, Ho WC, Hung SC, Hsu HS*. Particulate matter increases the severity of bleomycin-induced pulmonary fibrosis through KC-mediated neutrophil chemotaxis. Int J Mol Sci. 2020 Jan; 21(1): 227.
  16. Han-Shui Hsu, Chen-Chi Liu, Jiun-Han Lin, Tien-Wei Hsu, Jyuan-Wei Hsu, Anna Fen-Yau Li, Shih-Chieh Hung . Involvement of Collagen XVII in Pluripotency Gene Expression and Metabolic Reprogramming of Lung Cancer Stem Cells. J Biomed Sci. 2020 Jan 13;27(1):5. doi: 10.1186/s12929-019-0593-y.
  17. Hsu CP, Chuang CY, Hsu PK, Chien LI, Lin CH, Yeh YC, Hsu HS, Wu YC. Lymphovascular Invasion as the Major Prognostic Factor in Node-Negative Esophageal Cancer After Primary Esophagectomy. J Gastrointest Surg. 2020 Jul;24(7):1459-1468.
  18. Lin CM, Tu CC, Yeh YC, Hsu PK, Chien LI, Huang CS, Wu YC, Hsu HS. The Prognostic Impact of Extracapsular Lymph Node Involvement in Esophageal Squamous Cell Carcinoma. Ann Surg Oncol. 2020 Aug;27(8):3071-3082.
  19. Liu CY, Hsu PK, Hsu HS, Wu YC, Chuang CY, Lin CH, Hsu CP. Prognostic impact of circumferential resection margin in esophageal cancer with or without neoadjuvant chemoradiotherapy. Dis Esophagus. 2020 Sep 4;33(9):doz114.
  20. Lin YH, Chen CK, Hsieh CC, Hsu WH, Wu YC, Hung JJ, Hsu PK, Hsu HS*. Lymphadenectomy is Unnecessary for Pure Ground-Glass Opacity Pulmonary Nodules. J Clin Med. 2020 Mar 2;9(3):672.
  21. Huang CS, Hsu PK, Chen CK, Yeh YC, Hsu HS, Shih CC, Huang BS. Surgeons' preference sublobar resection for stage I NSCLC less than 3 cm. Thorac Cancer. 2020 Apr;11(4):907-917.
  22. Hung CT, Chen CK, Chang YY, Hsu PK, Hung JJ, Huang CS, Wu YC, Hsu HS. Electromagnetic navigation-guided versus computed tomography-guided percutaneous    localization     of    small    lung     nodules    before     uniportal video-assisted thoracoscopic surgery: a propensity score-matched analysis. Eur J Cardiothorac Surg. 2020 Aug 1;58(Supplement_1):i85-i91.
  23. Chang CJ, Chiang LL, Chen KY, Feng PH, Su CL, Hsu HS*. High-Flow Nasal Cannula versus Noninvasive Positive Pressure Ventilation in Patients with Heart Failure after Extubation: An Observational Cohort Study. Can Respir J. 2020 Jul 3;2020:6736475.
  24. Inciong JFB, Chaudhary A, Hsu HS, Joshi R, Seo JM, Trung LV, Ungpinitpong W, Usman N. Hospital malnutrition in northeast and southeast Asia: A systematic literature review. Clin Nutr ESPEN. 2020 Oct;39:30-45.
  25. Hung HY, Tseng YH, Chao HS, Chiu CH, Hsu WH, Hsu HS, Wu YC, Chou TY, Chen CK, Lan KL, Chen YW, Wu YH, Chen YM. Multidisciplinary team discussion results in survival benefit for patients with stage III non-small-cell lung cancer. LoS One. 2020 Oct 8;15(10):e0236503.
  26. Lin YH, Hsu HS*. Ground glass opacity on chest CT scans from screening to treatment: A literature review. J Chin Med Assoc. 2020 Oct;83(10):887-890.
  27. Hsu PK, Yeh YC, Chien LI, Huang CS, Hsu HS. Clinicopathological Significance of Pathologic Complete Lymph Node Regression After Neoadjuvant Chemoradiotherapy in Esophageal Squamous Cell Carcinoma. Ann Surg Oncol. 2020 Nov 20. doi: 10.1245/s10434-020-09363-z. Online ahead of print.
  28. Huang CS, Chien HC, Chen CK, Yeh YC, Hsu PK, Chen HS, Hsieh CC, Hsu HS, Huang BS, Shih CC. Significance of preoperative biopsy in radiological solid-dominant clinical stage I non-small-cell lung cancer. Interact Cardiovasc Thorac Surg. 2020 Dec 17;ivaa297. doi: 10.1093/icvts/ivaa297. Online ahead of print.
  29. Tsai PC, Hsu PK, Yeh YC, Chen CK, Chang YY, Huang CS, Hsu HS. Active surveillance or early resection for ground-glass nodules that need preoperative localization. J Surg Oncol. 2021 Jan;123(1):322-331.
  30. Yi-Chung Chen, Yi-Han Lin, Hung-Che Chien, Po-Kuei Hsu, Jung-Jyh Hung, Chien-Sheng Huang, Chih-Cheng Hsieh, Wen-Hu Hsu, Han-Shui Hsu*. Preoperative Consolidation-to-tumor ratio is effective in the prediction of lymph node metastasis in patients with pulmonary ground-glass component nodules. Thorac Cancer. 2021 Apr;12(8):1203-1209.
  31. Hsin-Hsien Li, Chen-Chi Liu, Tien-Wei Hsu, Jiun-Han Lin, Jyuan-Wei Hsu, Anna Fen-Yau Li, Yi-Chen Yeh, Shih-Chieh Hung, and Han-Shui Hsu*. Upregulation of ACE2 and TMPRSS2 by particulate matter and idiopathic pulmonary fibrosis: a potential role in severe COVID-19. Part Fibre Toxicol. 2021 Mar 11;18(1):11.
  32. Chan LY, Wang LC, Hsu HS*.Silent Angiomatoid Fibrous Histiocytoma of the Chest Wall. Ann Thorac Surg. 2021 May;111(5):e347-e348. doi: 10.1016/j.athoracsur.2020.08.063. Epub 2020 Nov 4.D: 33159863.
  33. Lin PY, Yen YT, Lam CT, Li KC, Lu MJ, Hsu HS*. Use of modified-NUTRIC score to assess nutritional risk in surgical intensive care unit.J Chin Med Assoc. 2021 Jun 8. doi: 10.1097/JCMA.0000000000000565. Online ahead of print.PMID: 34108425.
  34. Po-Kuei Hsu, Ling-I Chien, Chien-Sheng Huang, Yi-Chen Yeh, Pin-I Huang, Ming-Huang Chen, Sheng-Yu Chen, Chueh-Chuan Yen, Han-Shui Hsu. ASO Visual Abstract: Treatment Patterns and Outcomes for Patients with Esophageal Cancer-An Analysis of a Multidisciplinary Tumor Board Database. Ann Surg Oncol. 2022 Jan;29(1):572-585. doi: 10.1245/s10434-021-10568-z. Epub 2021 Aug 13.
  35. Hui-Chun Chang, Chung-Han Ho, Shu-Chen Kung, Wan-Lin Chen, Ching-Min Wang, Kuo-Chen Cheng, Wei-Lun Liu, Han-Shui Hsu. Maintenance of low driving pressure in patients with early acute respiratory distress syndrome significantly affects outcomes. Respir Res. 2021 Dec 15;22(1):313. doi: 10.1186/s12931-021-01912-8.