蔡尚聞 主治醫師 Shang-Wen Tsai, Asst.Prof

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現職
臺北榮總關節重建科 主治醫師
中國民國關節重建醫學會 理事
台灣人工關節教育學會 秘書長
WEM國際人工膝髖關節專家會議 台灣代表
ICM國際感染共識專家會議 台灣代表
國際期刊BMC Musculoskeletal Disorders編輯
中華民國骨科醫學會官方期刊 編輯
中華民國骨科醫學會 幹事
國立陽明交通大學 教育部部定助理教授

學歷
國立成功大學醫學系畢業

經歷
臺北榮總 住院醫師
臺北榮總 總醫師
臺北榮總 研究醫師
臺北榮總 骨科部主治醫師
美國費城Rothman Orthopedic Institute進修

1. 微創正前開人工髖關節置換(DAA)
2. 人工關節感染

主治項目
膝、髖退化性關節炎疼痛及注射治療
膝關節骨壞死
股骨頭缺血性壞死
X型腿、O型腿矯正
骨折創傷後癒合不正、變形
人工膝髖關節併發症
人工關節置換手術後疼痛
人工關節零件鬆動
人工髖關節反覆脫臼
人工膝髖關節旁骨折
人工關節感染
肌肉骨骼系統腫瘤
骨轉移及病理性骨折

專長
微創正前開人工髖關節置換手術 (DAA)
微創英式活動半膝人工關節置換手術
微創全膝人工關節置換手術
3D列印輔助高位脛骨截骨矯正手術、遠端股骨截骨矯正手術
複雜人工膝髖關節再置換手術
各類骨折創傷手術

研究
醫學論文(僅列出SCI文章)

1.   Tsai SW, Tsai CL, Wu PT, Wu CY, Liu CL, Jou IM. Intraoperative use of somatosensory-evoked potential in monitoring nerve roots. J Clin Neurophysiol. 2012 Apr;29(2):110-7.
   術中以誘發電位監測神經根之系統性回顧
    
2. Tsai SW, Chen CF, Wu PK, Chen TH, Liu CL, Chen WM. Modified anterolateral approach in minimally invasive total hip arthroplasty. Hip Int. 2015 May-Jun;25(3):245-50.
   前外側切口行微創全人工髖關節置換手術技術介紹
    
3. Tsai SW, Wu PK, Chen CF, Chiang CC, Huang CK, Chen TH, Liu CL, Chen WM. Etiologies and outcome of osteonecrosis of the femoral head: Etiology and outcome study in a Taiwan population. J Chin Med Assoc. 2015 Sep 17.
   台灣族群發生股骨頭缺血性壞死的流行病學以及相關預後
    
4. Tsai SW, Chen CF, Wu PK, Huang CK, Chen WM, Chang MC. Does Implant Selection Impact Postoperative Complications Following Hip Arthroplasty for Failed Intertrochanteric Fractures? A Retrospective Comparative Study. Artif Organs. 2016 Jan 27.
   不同人工關節置換手術方法治療股骨轉子間骨折之結果比較
    
5. Tsai SW, Wu PK, Chen CF, Chang MC, Chen WM. Postoperative Ambulatory Performance Status Significantly Affects Implant Failure Rate Among Surgical Treatment Strategies in Patients With Proximal Femur Metastasis. Artif Organs. 2016 Nov 8.                                   
   不同手術方式治療近端股骨轉移性病灶之結果比較
    
6. Chen KH, Tsai SW, Wu PK, Chen CF, Wang HY, Chen WM. Partial component-retained two-stage reconstruction for chronic infection after uncemented total hip arthroplasty: results of sixteen cases after five years of follow-up. Int Orthop. 2017 May 27.                                   
   僅移除部分人工髖關節組件以治療人工髖關節慢性感染之手術經驗
    
7. Tsai SW, Chen CF, Wu PK, Chen CM, Chen WM. Revision Total Knee Arthroplasty Using a Constrained Condylar Knee Prosthesis Combined with a Posterior Stabilized Articular Surface. J Knee Surg. 2017 May 23.          
   以非限制型墊片行人工膝關節再置換之臨床經驗
    
8. Tsai SW, Lin CJ, Tzeng YH, Lin CC, Huang CK, Chang MC, Chiang CC. Risk factors for cut-out failure of Gamma3 nails in treating unstable intertrochanteric fractures: An analysis of 176 patients. J Chin Med Assoc. 2017 Jun 7.               
   分析Gamma3髓內釘治療不穩定型股骨轉子間骨折失敗之危險因子
    
9. Yang TC, Chen CF, Tsai SW, Chen WM, Chang MC. Does restoration of hip center with subtrochanteric osteotomy provide preferable outcome for Crowe type III-IV irreducible development dysplasia of the hip? J Chin Med Assoc. 2017 Jul 5.
   股骨轉子下截骨合併人工髖關節手術重建高度髖臼發育不全之臨床經驗
    
10. Chen CM, Wu PK, Tsai SW, Chen CF, Chen WM. Prognosis-based shoulder hemiarthroplasty after resection of proximal humeral malignancy. Artif Organs. 2017 Jul 19.                                                
    近端肱骨惡性骨腫瘤切除後功能性重建的臨床經驗
     
11. Tsai SW, Chen CF, Wu PK, Chen CM, Chen WM. Cement augmentation in the proximal femur to prevent stem subsidence in revision hip arthroplasty with Paprosky type II/IIIa defects. J Chin Med Assoc. 2017 Feb 8.                           
    在人工髖關節再置換手術當中以骨水泥處理股骨近端骨缺損的臨床經驗
     
12. Wu PK, Chen CF, Chen CM, Cheng YC, Tsai SW, Chen TH, Chen WM. Intraoperative extracorporeal irradiation and frozen treatment on tumor-bearing autografts show equivalent outcomes for biologic reconstruction. Clin Orthop Relat Res. 2018 Apr.                                        
    比較以液態氮冷凍以及體外放射線照射治療惡性骨腫瘤併重建之臨床結果
     
13. Wu PK, Chen CF, Chen CM, Tsai SW, Cheng YC, Chang MC, Chen WM. Grafting for bone defects after curettage of benign bone tumor – analysis of factors influencing the bone healing. J Chin Med Assoc. 2018 Jul.                                  
    良性骨腫瘤接受刮除及骨移植手術後，影響骨癒合之因子分析
     
14. Lin YK, Wu PK, Chen CF, Chen CM, Tsai SW, Chen CH, Chen WM. Alveolar soft part sarcoma: Clinical presentation, treatment, and outcome in a series of 13 patients. J Chin Med Assoc. 2018 Aug.                                                        
    肺泡軟組織肉瘤：臨床表現以及治療結果呈現
     
15. Chang CH, Tsai SW, Chen CF, Wu PK, Wong WW, Chang MC, Chen WM. Optimal timing for elective total hip replacement in HIV-positive patients. Orthop Traumatol Surg Res. 2018 Sep.                                
    愛滋病患合併股骨頭缺血性壞死，接受全人工髖關節置換手術之時機評估以及治療結果呈現
     
16. Chen CF, Chu HC, Chen CM, Cheng YC, Tsai SW, Chang MC, Chen WM, Wu PK. A safety comparative study between freezing nitrogen ethanol composite and liquid nitrogen for cryotherapy of musculoskeletal tumors. Cryobiology 2018 Aug.                                                                                
    不同冷凍療法治療肌肉骨骼腫瘤的安全性評估：老鼠動物模型
     
17. Chen CF, Tsai SW, Wu PK, Chen CM, Chen WM. Does continued aspirin mono-therapy lead to a higher bleeding risk after total knee arthroplasty? J Chin Med Assoc. 2018 Sep.                                          
    針對接受全人工膝關節置換手術的病患繼續使用口服阿斯匹靈藥物的安全性評估
     
18. Lo IN, Tsai SW, Wu PK, Chen CF, Chang MC, Chen WM. The mid-term outcome of dialysis-dependent patients undergoing primary total knee arthroplasty and total hip arthroplasty: A retrospective study. J Chin Med Assoc. 2019 Feb.    
    洗腎病患接受全人工膝或髖關節手術後臨床成果呈現
     
19. Hsu KH, Tsai SW, Chen CF, Chang MC, Chen WM. The risk factors of early acetabular failure after bipolar hemiarthroplasty because of fracture of the femoral neck. J Chin Med Assoc. 2019 Mar.                             
    股骨頸骨折接受半髖置換手術後早期失敗因素分析
     
20. Chang CH, Tsai SW, Hsu KH, Chang MC, Chen WM, Su YP. The efficacy of a drug holiday test on two-stage revision for infected total knee arthroplasty. J Chin Med Assoc. 2019 Mar.                                          
    人工膝關節感染接受階段手術治療期間的抗生素治療準則及其結果呈現
     
21. Cheng YC, Wu PK, Chen CF, Chen CM, Tsai SW, Chang MC, Chen WM. Analysis of learning curve of minimally invasive total knee arthroplasty: A single surgeon’s experience with 4017 cases over a nine-year period. J Chin Med Assoc. 2019 Apr.                                                  
    微創人工膝關節手術技術介紹以及臨床結果呈現
     
22. Chen CM, Chen CF, Wang JY, Madda R, Tsai SW, Wu PK, Chen WM. Bone morphogenetic protein activity with extracorporeal irradiation and liquid nitrogen freezing-treated recycled autografts for biological reconstruction in malignant bone tumor. Cryobiology. 2019 May.                        
    比較體外放射線照射以及液態氮冷凍對於BMP-2蛋白質活性表現之影響
     
23. Ma HH, Chou TFA, Tsai SW, Chen CF, Wu PK, Chen WM. The efficacy of intraoperative periarticular injection in total hip arthroplasty: a systematic review and meta-analysis. BMC Musculoskelet Disord. 2019 Jun.         
    關節內局部止痛注射應用在全人工髖關節手術之治療成效
     
24. Chang CH, Tsai SW, Wu PK, Chen CM, Chang MC, Chen WM, Chen CF. Suboptimal outcomes after internal fixation for displaced intracapsular femoral neck fractures in 50- to 60-year-old patients. Hip Int. 2019 Jun.   
    移位性股骨頸骨折在年輕族群之整體治療結果及失敗之危險因子
     
25. Ma HH, Chou TFA, Tsai SW, Chen CF, Wu PK, Chen WM. The efficacy and safety of continuous versus single-injection popliteal sciatic nerve block in outpatient foot and ankle surgery: a systematic review and meta-analysis. BMC Musculoskelet Disord. 2019 Oct.                                 
    比較兩種不同膝後坐骨神經阻斷術在足踝手術之止痛成效
     
26. Ma HH, Chou TFA, Tsai SW, Chen CF, Wu PK, Chen WM. Outcomes of internal fixation versus hemiarthroplasty for elderly patients with an undisplaced femoral neck fracture: a systematic review and meta-analysis. J Orthop Surg Res. 2019 Oct. 
    比較骨折內固定手術及半髖人工關節置換手術在老年族群合併非移位性股骨頸骨折之治療結果
     
27. Ma HH, Chou TFA, Tsai SW, Chen CF, Wu PK, Chen CM, Chen WM. Is short-course systemic antibiotic therapy using an antibiotic-loaded cement spacer safe after resection for infected total knee arthroplasty? A comparative study. J Formos Med Assoc. 2019 Oct.                      
    人工膝關節感染經人工關節移除手術使用較短週期的抗生素治療之臨床結果
     
28. Wang JH, Ma HH, Chou TFA, Tsai SW, Chen CF, Wu PK, Chen WM. Outcomes following total elbow arthroplasty for rheumatoid arthritis versus post-traumatic conditions. Bone Joint J. 2019 Dec.
    類風濕性關節炎及創傷肘關節病變接受人工肘關節置換手術後之結果比較
     
29. Tsai SW, Ma HH, Hsu FW, Chou TFA, Chen KH, Chiang CC, Chen WM. Risk factors for refracture after plate removal for midshaft clavicle fracture after bone union. J Orthop Surg Res. 2019 Dec.
    中段鎖骨骨折移除鋼板後發生再次骨折的危險因子分析
     
30. Tsai MC, Ng YY, Chen WM, Tsai SW, Wu SC. The effect of cement fixation on survival in elderly patients with hip hemiarthroplasty: a nationwide cohort study. BMC Musculoskelet Disord. 2019 Dec.
    健保資料庫統計，分析骨水泥應用於半人工髖關節手術之結果報告
     
31. Ma HH, Chou TFA, Tsai SW, Chen CF, Wu PK, Chen WM. The efficacy of continuous versus single-injection femoral nerve block in total knee arthroplasty: a systematic review and meta-analysis. BMC Musculoskelet Disord. 2020 Feb.
    較兩種不同方式的股骨神經阻斷術在人工膝關節手術之止痛成效  
     
32. Chen YC, Wu PK, Chen CM, Tsai SW, Chen CF, Chen WM. Prognostic factors and survival in conventional chondrosarcoma: A single institution review. J Chin Med Assoc. 2020 Mar.  
    分析軟骨肉癌整體的預後以及相關因子
     
33. Chou TFA, Ma HH, Wang JH, Tsai SW, Chen CF, Wu PK, Chen WM. Total elbow arthroplasty in patients with rheumatoid arthritis: A systematic review and meta-analysis. Bone Joint J. 2020 Aug.                            
    類風濕性關節炎病患接受人工肘關節置換手術後的結果分析
     
34. Yeung CY, Tsai SW, Wu PK, Chen CF, Chang MC, Chen WM. Low rates of all-cause revision in displaced subcapital femoral neck fractures treated with hemiarthroplasty – a retrospective review of 4516 patients from a single institute. BMC Musculoskelet Disord. 2020 Oct.
    分析半人工髖關節在治療移位性股骨頸骨折的臨床結果
     
35. Wang PH, Tsai SW, Chen CF, Wu PK, Chen CM, Chang MC, Chen WM. Cementation of the polyethylene liner into a well-fixed acetabular shell to treat patients with recurrent dislocation after total hip arthroplasty. Artif Organs. 2020 (accepted)
    以骨水泥協助固定聚乙烯髖臼墊片以治療反覆性髖關節脫臼的臨床結果
     
36. Ma HH, Tsai SW, Chen CF, Wu PK, Chen CM, Chiang CC, Chen WM.     Impact of screening COVID-19 on orthopedic trauma patients at the emergency department: A consecutive series from a level I trauma center. J Chin Med Assoc. 2021 Apr.
    於急診篩檢新冠肺炎(COVID-19)對於骨折創傷病人治療結果的影響
     
37. Ma HH, Chou TA, Pai FY, Tsai SW, Chen CF, Wu PK, Chen WM.      Outcomes of dual-mobility total hip arthroplasty versus bipolar hemiarthroplasty for patients with femoral neck fractures: a systematic review and meta-analysis. J Orthop Surg Res. 2021 Feb.                  
    使用雙極式全人工髖關節以及半人工髖關節手術治療股骨頸骨折之結果比較
     
38. Ma HH, Chou TA, Tsai SW, Chen CF, Wu PK, Chen WM.
    Uncemented femoral stem design might have an impact on postoperative periprosthetic femur fracture pattern. A comparison between flat-wedge and dual-wedge stems. Injury. 2021 Feb.                              
    描述不同的人工髖關節股骨柄的設計對於人工髖關節旁骨折型態之影響
     
39. Ma HH, Chou TA, Wang HY, Tsai SW, Chen CF, Wu PK, Chen WM.          
    An opioid-sparing protocol with intravenous parecoxib can effectively reduce morphine consumption after simultaneous bilateral total knee arthroplasty. Sci Rep. 2021 Apr.                                                
    人工膝關節置換手術後之止痛模式能有效降低嗎啡類藥物使用量: 臺北榮總微創人工關節重建團隊經驗
     
40. Pai FY, Ma HH, Chou TA, Huang TW, Huang KC, Tsai SW, Chen CF, Chen WM. Risk factors and modes of failure in the modern dual mobility implant. A systematic review and meta-analysis. BMC Musculoskelet Disord. 2021 Jun.
    雙極式全人工髖關節的失敗模式及其危險因子分析
     
41. Lin YK, Tsai SW, Wu PK, Chen CM, Yang JC, Chen CF, Chen WM. Significantly reducing blood loss via a peri-articular injection of tranexamic acid during total knee arthroplasty: a retrospective study. BMC Musculoskelet Disord. 2021 Aug.               
    關節內局部注射傳明酸以降低人工膝關節置換手術出血的臨床經驗
     
42. Chen KL, Chen CM, Chen CF, Cheng YC, Lin YK, Tsai SW, Chen TH, Wu PK, Chen WM. Comparable outcomes of recycled autografts and allografts for reconstructions in patients with high-grade osteosarcoma. Int Orthop. 2021 Aug.
    使用自體骨滅活或是異體骨進行生物性重建以治療骨肉瘤的臨床經驗
     
43. Chen CF, Chen YC, Fu YS, Tsai SW, Wu PK, Chen CM, Chang MC, Chen WM. Characterization of osteogenesis and chondrogenesis of human decellularized allogeneic bone with mesenchymal stem cells derived from bone marrow, adipose tissue, and Wharton’s jelly. Int J Mol Sci. 2021 Aug.  
    比較使用骨髓、脂肪或是臍帶幹細胞合併異體骨之骨生長及軟骨生長現象
     
44. Chou TA, Ma HH, Tsai SW, Chen CF, Wu PK, Chen WM. Dialysis patients have comparable results to patients who had received kidney transplant after total joint arthroplasty: a systematic review and meta-analysis. EFORT Open Rev. 2021 (accepted)
    洗腎患者與腎臟移植患者接受全人工膝或髖關節置換手術之臨床結果呈現
     
45. Wang JH, Ma HH, Chou TA, Tsai SW, Chen CF, Wu PK, Chen WM. Does the addition of iPACK block to adductor canal block provide improved analgesic effect in total knee arthroplasty? A systematic review and meta-analysis. J Knee Surg. 2021 (accepted)  
    膝後窩阻斷注射合併內收肌通道神經阻斷於人工膝關節置換手術之止痛成效
     
46. Chen CF, Yu YB, Tsai SW, Chiu JW, Hsiao LT, Gau JP, Hsu HC. Total knee replacement for patients with severe hemophilic arthropathy in Taiwan: A national population-based retrospective study. J Chin Med Assoc. 2022 Feb.
    以人工膝關節手術治療血友病合併嚴重膝關節病變的臨床成效
     
47. Ma HH, Chou TA, Tsai SW, Chen CF, Wu PK, Chen WM. Is there a role for cementless primary stem in hip arthroplasty for early or late fixation failures of intertrochanteric fractures? BMC Musculoskelet Disord. 2022 Mar.      
    以不同人工髖關節股骨柄治療髖骨轉子間骨折固定失敗的臨床結果分析
     
48. Tsai SW, Chou TA, Chen WM. Recommendations from the ICM-VTE: Oncology. J Bone Joint Surg Am. 2022 Mar.                                      
    骨腫瘤手術期間預防靜脈血栓的國際臨床共識
     
49. Pai FY, Chang WL, Tsai SW, Chen CF, Wu PK, Chen WM. Pharmacological thromboprophylaxis as a risk factor for early periprosthetic joint infection following primary total joint arthroplasty. Sci Rep. 2022 Jun. (Accepted).  
    以抗凝血藥物預防人工膝髖關節手術後靜脈血栓的相關感染風險分析
     
50. Pai FY, Chou TA, Ma HH, Chang WL, Tsai SW, Chen CF, Wu PK, Chen WM.Cementless primary or revision in revision hip arthroplasty for aseptic stem loosening with Paprosky type I/II femoral defect? J Chin Med Assoc. 2022 Nov
    人工髖關節股骨柄鬆動再置換手術時的股骨柄選擇擊技術解析
     
51. Chen YC, Fu YS, Tsai SW, Wu PK, Chen CM, Chen WM, Chen CF.
    IL-1b in the secretomes of MSCs seeded on human decellularized allogeneic bone promotes angiogenesis. Int J Mol Sci. 2022 Dec.
    驗證間葉幹細胞植入人體異體骨的血管新生能力以及相關機轉
     
52. Chou TA, Ma HH, Tsai CW, Tsai SW, Chen CF, Chiu FY, Wu PK, Chen WM.
    The safety and cost-analysis of simultaneous versus staged bilateral total knee arthroplasty in a Taiwan population. J Chin Med Assoc. 2023 Feb.
    同時或是分次接受雙側全人工膝關節置換手術的安全性以及費用效益分析
     
53. Lee KH, Chang WL, Tsai SW, Chen CF, Wu PK, Chen WM.
    The impact of Charlson Comorbidity Index on surgical complications and reoperations following simultaneous bilateral total knee arthroplasty. Sci Rep. 2023 Apr.
    以Charlson Comorbidity Index(疾病嚴重程度指標)預測同時接受雙側人工
    關節手術病患產生併發症以及再次手術的風險
     
54. Tsai SW, Chang WL, Pai FY, Chou TA, Chen CF, Wu PK, Chen WM.
    Combination of enoxaparin and low-dose aspirin for thromboprophylaxis in selective patients after primary total joint arthroplasty in a Taiwanese population. J Chin Med Assoc. 2023 Aug.
    以低分子量肝素以及阿斯匹靈預防人工膝髖關節術後靜脈血栓的臨床經驗
     
55. Chen CF, Chen YC, Fu YS, Tsai SW, Wu PK, Chen CM, Chen WM, Wu HT, Lee CH, Chang CL, Lin PC, Kao YC, Chen CH, Chuang MH.
    Safety and tolerability of intra-articular injection of adipose-derived mesenchymal stem cells GXCPC1 in 11 subjects with knee osteoarthritis: A nonrandomized pilot study without a control arm. Cell Transplant. 2024 Jan-Dec.
    以脂肪幹細胞局部注射治療膝關節炎的臨床安全性及耐受度評估
     
56. Chang WL, Pai FY, Tsai SW, Chen CF, Wu PK, Chen WM.
    Risk Factors for Venous thromboembolism after primary total joint arthroplasty: an analysis of 7511 Taiwanese patients. J Chin Med Assoc. 2024 Mar.
    接受初次人工膝髖關節置換手術後靜脈血栓事件之危險因子分析
     
57. Hung YT, Lee KH, Chang WL, Tsai SW, Chen CF, Wu PK, Chen WM.
    Routine use of structural allograft in medial open wedge high tibial osteotomy: satisfactory outcomes regardless of a lateral hinge fracture. Ortho J Sport Med. 2024 Apr (accepted).
    常規使用異體骨填充輔助高位脛骨截骨矯正手術之臨床成果